Active surveillance (AS) is the preferred strategy for favorable-risk prostate cancer, yet current protocols rely on scheduled repeat biopsies, most of which reveal no progression and are unnecessary. Existing risk-stratification tools operate on single time-point imaging or depend on explicit lesion segmentation, limiting their ability to capture longitudinal change and excluding patients without an MRI-visible lesion.
arXiv:2510. 17529v3 Announce Type: replace-cross Abstract: Active Surveillance (AS) is a treatment option for managing low and intermediate-risk prostate cancer (PCa), aiming to avoid overtreatment while monitoring disease progression through serial MRI and clinical follow-up.
arXiv:2607. 06919v1 Announce Type: cross Abstract: Artificial intelligence (AI) analysis of micro-ultrasound ($\mu$US) has shown promise for prostate cancer (PCa) detection.
arXiv:2607. 04912v1 Announce Type: cross Abstract: In patients with breast cancer, pathological complete response (pCR) has been established as a clinically meaningful surrogate marker for long-term outcomes.
arXiv:2608.21497v1 Announce Type: cross Abstract: Biochemical recurrence (BCR), defined as any detectable prostate-specific antigen level after prostatectomy with confirmatory elevation, is widely us...
The paper introduces ANT, a test‑time adaptation framework that improves prostate cancer detection in micro‑ultrasound by performing a segmentation‑guided adaptation. ANT aligns a pretrained detection encoder to the target domain’s prostate anatomy using pseudo‑masks from a frozen segmentation network, thereby correcting domain‑specific feature drift while preserving cancer‑discriminative features. In a leave‑one‑center‑out evaluation, ANT raises mean AUC by 2.9% at the biopsy‑core level and 3.6% at the patient level compared to no adaptation, outperforming existing TTA baselines.
arXiv:2606. 30951v1 Announce Type: cross Abstract: Micro-ultrasound ($\mu$US) is a new, emerging, and promising imaging modality for prostate cancer (PCa) detection, but accurate identification of suspicious tissue remains highly dependent on clinical experience, leading to substantial inter-observer variability.
PCaPaint is a prostate cancer inpainting method that uses latent diffusion models (LDMs) and introduces a conditioning strategy where the condition image is filled with Gaussian noise to mitigate shortcut learning. It also proposes a new training objective that focuses on errors within the lesion region and a multi‑sequence latent design that separately compresses T2w and DWI&ADC scans to preserve their distinct frequency characteristics. Experiments show that the synthetic data generated by PCaPaint improves downstream tasks such as prostate lesion segmentation, patient‑level classification, and lesion‑level detection, outperforming recent state‑of‑the‑art LDM‑based tumor inpainting methods in both performance and image quality.
arXiv:2604. 22700v2 Announce Type: replace Abstract: Modeling and predicting neurodegenerative disease progression from medical images remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning.
arXiv:2512.08029v4 Announce Type: replace Abstract: Clinical decision-making in oncology requires forecasting how disease evolves under treatment, yet most AI systems remain static predictors that ca...
Many clinical prediction models treat post-intervention outcomes as a one-step mapping from baseline measurements to a future endpoint. However, recovery after a procedure often unfolds as an irregular trajectory: clinical observations, medication changes, repeat interventions, and physiological measurements are recorded asynchronously and can change risk assessment over time.
arXiv:2607. 16260v1 Announce Type: cross Abstract: Multimodal survival analysis utilizing whole slide images (WSIs) and genomic profiles is fundamental for cancer prognosis.
Accurate prognosis prediction is important for treatment planning in lung cancer, but deep learning-driven survival modelling is often limited by the scarcity of curated imaging cohorts with reliable outcome data. This study evaluates whether representations from a domain-specific foundation model can be used for multimodal survival prediction in data-constrained clinical settings.