arXiv AI

KnowBench: Effort Reduction as a Unified, Deployment-Grounded Benchmark for Clinical AI

KnowBench is a new benchmark for clinical AI that measures Effort Reduction (ER), the proportion of system-generated clinical work product accepted by clinicians after expert and safety review. The metric is applied uniformly across various administrative tasks—visit notes, billing codes, orders, EHR summarization, patient summaries, and decision support—using the clinician’s review-and-attestation as ground truth. An initial deployment of Knowtex’s models achieved an aggregate ER of 97.99% across more than one million encounters in six months, with specialty-specific ER ranging from 96.8% to 98.9%.

arXiv AI
Aug 11

CliniCARE-Bench: Clinical Calibrated Audit of Medical Reasoning in EHR

arXiv:2608. 07796v1 Announce Type: new Abstract: Large language models perform strongly on medical knowledge benchmarks, but reliable clinical deployment requires agents to conduct defensible investigations over heterogeneous, longitudinal records: determining what evidence is needed, retrieving and reconciling structured and free-text data, grounding conclusions in verifiable evidence, and deferring cases that cannot be resolved reliably.

By Veronica Chatrath, Bryan Zhu, George Pu, Jingxuan Fan, Apaar Shanker, Varun Ursekar, Anahita Sharma, Jason Qin, Keqi Han, Soham Dinesh Tiwari, Soham Dan, Vijay Kalmath, Yuan Li, Daniel Yue Zhang, Chenguang Wang, Zainab Doctor, Zhijun Yin, Nigam H. Shah, Yuan Xue
arXiv AI
Jul 28

OpenAIs HealthBench in Action: Evaluating an LLM-Based Medical Assistant on Realistic Clinical Queries

arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.

By Sandhanakrishnan Ravichandran, Shivesh Kumar, Rogerio Corga Da Silva, Miguel Romano, Reinhard Berkels, Michiel van der Heijden, Olivier Fail, Valentine Emmanuel Gnanapragasam
arXiv AI
Jul 29

PatientAgentBench: A Benchmark Framework for Evaluating Patient-Facing Health AI Agents

arXiv:2607. 25485v1 Announce Type: new Abstract: Health AI is evolving from answering questions to agentic systems that converse with patients, reason about health records, and act on their behalf.

By Korosh Vatanparvar, Ashutosh Joshi, Maria Xenochristou, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Daniel Lopez-Martinez, Anchal Nema, Ramya Ganesan, Will Kimbrough, Alex Woody, Yadunandana Rao, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
arXiv AI
Jul 15

First, do NOHARM: a medical safety benchmark and randomized study of physician and AI teaming on clinical consultations

arXiv:2512. 01241v4 Announce Type: replace-cross Abstract: Large language models (LLMs) and medical AI tools are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized.

By David Wu, Fateme Nateghi Haredasht, Saloni Kumar Maharaj, Priyank Jain, Jessica Tran, Matthew Gwiazdon, Arjun Rustagi, Jenelle Jindal, Jacob M. Koshy, Vinay Kadiyala, Anup Agarwal, Bassman Tappuni, Brianna French, Sirus Jesudasen, Christopher V. Cosgriff, Rebanta Chakraborty, Jillian Caldwell, Susan Ziolkowski, David J. Iberri, Robert Diep, Rahul S. Dalal, Kira L. Newman, Kristin Galetta, J. Carl Pallais, Nancy Wei, Kathleen M. Buchheit, David I. Hong, Vartan Pahalyants, Ernest Y. Lee, Allen Shih, Tamara B. Kaplan, Vishnu Ravi, Sarita Khemani, Thomas A. Buckley, April S. Liang, Daniel Shirvani, Advait Patil, Nicholas Marshall, Kanav Chopra, Joel Koh, Adi Badhwar, Anastasia Perez, Austin J. Schoeffler, Mahbuba Tusty, Chase M. Walton, Liam G. McCoy, David J. H. Wu, Yingjie Weng, Sumant Ranji, Kevin Schulman, Nigam H. Shah, Jason Hom, Arnold Milstein, Arjun K. Manrai, Adam Rodman, Jonathan H. Chen, Ethan Goh
arXiv AI
Sep 15

Same Patient, Different Order: Action-Level Reliability of Clinical LLM Agents Under Repeated Runs

The paper introduces a new evaluation method called "same-input rerun" to assess the consistency of clinical language‑model agents across repeated runs. By replaying 1,000 MedAgentBench tasks with identical inputs, the authors find that action‑level outputs—such as test orders, medication requests, and referrals—vary significantly, even when benchmark scores remain unchanged. The study demonstrates that current benchmarks, which typically evaluate only a single run per task, can miss substantial behavioral divergence.

By Rohith Reddy Bellibatlu, Manpreet Singh, Zhoutian Han, Wenbin Zhang
arXiv AI
1d ago

DAYJOB: A Benchmark for Long-Horizon Professional Work

DAYJOB is a new benchmark comprising 130 long‑horizon professional tasks created by experts in healthcare (50 tasks) and finance (80 tasks). Each task is packaged as a containerized Harbor environment and evaluated against a detailed binary rubric, requiring agents to meet every criterion to pass. In tests across 30 model configurations, the best model (Claude Opus 5.5) achieves about 24% success in both domains, while the median model scores below 3%.

By Stephanie Finley, Liudas Panavas, Thomas Mikkelson, Cam Hinton, Stacey Ganss, Bradley Monton, Emily Kendall, Michelle Spradlin, Lydia Bye, Michael O'Brien, Lauren Ylvisaker, Derek Ray, Suhaas Garre, Sushant Mehta, Edwin Chen