The paper introduces a lightweight Cross‑Layer Fusion Adapter (CLFA) that adapts the CLIP vision‑language model for handwriting‑based Alzheimer's disease screening. CLFA inserts multi‑level adapters into a frozen visual encoder, fusing cross‑layer features with depthwise 2D convolutions to capture both local stroke irregularities and higher‑level handwriting structure. On the Darwin dataset, CLFA achieves 74.63% AUC, 74.85% accuracy, and 73.72% F1, outperforming the best competing model by 2.15, 1.79, and 1.87 percentage points across 600 task‑disjoint source‑target pairs.
By Changqing Gong, Huafeng Qin, Mounim A. El-Yacoubi
The paper presents a two‑stage method for recovering handwriting trajectories from static images. First, it predicts ordered stroke instances autoregressively, then reconstructs continuous motion within each stroke using direction‑related cues. Experiments on Chinese, English, and Tamil handwriting show that this ordered prediction outperforms post‑hoc ordering and baseline models, and that sampling density significantly impacts performance.
By En-Guang Wang, Yan-Ming Zhang, Fei Yin, Cheng-Lin Liu
arXiv:2607. 12500v1 Announce Type: new Abstract: Deep learning models for online handwriting recognition have been shown effective and are increasingly deployed in practical applications.
By Yataro Tamura, Brian Kenji Iwana, Jiseok Lee
arXiv:2602. 11177v2 Announce Type: replace-cross Abstract: Reliable early detection of Alzheimer's disease (AD) is challenging, particularly due to the limited availability of labeled data.
By Lei Jiang, Yue Zhou, Natalie Parde
arXiv:2609.17565v1 Announce Type: new
Abstract: Online handwriting recognition systems typically represent pen trajectories through fixed-length Euclidean shape descriptors that capture the spatial o...
By Hassan Ugail, Newton Howard
arXiv:2606. 24604v1 Announce Type: new Abstract: Longitudinal modelling of Alzheimer's disease progression is clinically useful only if it can describe not just the most likely next diagnosis, but how a patient may evolve over time and how reliable that forecast is.
By Arya Hariharan, Shreyank N Gowda, Anala M R
arXiv:2606. 09671v1 Announce Type: cross Abstract: Alzheimer's disease (AD) progression is highly heterogeneous and is typically observed through sparse and irregular longitudinal data, posing challenges for prediction and personalised monitoring.
By Yinyu Huang, Yilin Zhang, Sofia Michopoulou, Christopher Kipps, Rahman Attar
The paper presents a diagnostic framework for Alzheimer’s disease that uses the Large Brain Model (LaBraM), a foundation model pretrained on over 2,500 hours of EEG data, to generate high‑dimensional latent embeddings. These embeddings are fed into a non‑linear Random Forest classifier, achieving an ROC‑AUC of 89.36% ± 3.49%, PR AUC of 81.45% ± 4.43%, and Balanced Accuracy of 82.44% ± 4.34% in a subject‑independent 5‑fold cross‑validation setting, using only 8‑second EEG segments. Post‑hoc occlusion and neurophysiological alignment analyses confirm that the model captures clinically validated biomarkers such as occipital‑frontal Alpha and Theta rhythm degradation and correlates with cognitive performance and clinical severity.
By Maggie Lin, Chung-Lin Hou, Tzyy-Ping Jung
Longitudinal modelling of Alzheimer's disease progression is clinically useful only if it can describe not just the most likely next diagnosis, but how a patient may evolve over time and how reliable that forecast is. Most deep learning approaches reduce this problem to single-step classification, treating cognitively normal, mild cognitive impairment, and dementia as flat categories while providing limited insight into how uncertainty accumulates across future visits.
The paper introduces a reverse spatio‑temporal disease progression model that reconstructs unobserved healthier anatomy from later diseased scans. It employs a two‑stage architecture: a frozen 3D vector‑quantised autoencoder creates a discrete latent space, and a Neural ODE learns continuous‑time dynamics, with a recurrent encoder initializing the latent state from reverse‑ordered observations. Experiments on a synthetic Morpho‑MNIST benchmark and longitudinal Alzheimer’s MRIs show the model can recover unseen prior states and outperform baseline methods in predicting healthy trajectories.
By Ulugbek Shernazarov, Moucheng Xu, Inomjon Ramatov
arXiv:2609.15888v1 Announce Type: cross
Abstract: Deep networks trained on structural MRI for Alzheimer's disease (AD) staging often reach reasonable accuracy while attending to anatomically irreleva...
By Paul-Gabriel Nicolae, Irina Georgiana Mocanu
DiaSeg extracts diagonal segments from Dynamic Time Warping (DTW) paths, characterizing each with five geometric features to preserve local alignment information. In a study of 91 subjects across six clinical conditions, these segments revealed consistent unsupervised patterns aligned with biomechanical phases and achieved near-perfect separation of healthy and pathological gait. While cycle‑based methods reached higher overall accuracy, DiaSeg offers phase‑specific interpretability, pinpointing where coordination breaks down within the gait cycle.
By Tresor Y. Koffi, Amel Hidouri, Corentin Legrand, Aur\'elie Bertaux