arXiv AI

CPAgents: Agentic Composite Phenotype Generation for Cardiac Disease Association

arXiv:2606. 28179v1 Announce Type: cross Abstract: Identifying robust associations between cardiac imaging phenotypes and clinical diseases is fundamental to population-scale cardiovascular research and reliable risk stratification.

arXiv AI
Jun 2

CardioLens: Revealing the Clinical Reality Gap of MLLMs via Multi-Sequence Cardiac MRI Evaluations

arXiv:2606. 00123v1 Announce Type: cross Abstract: Multimodal Large Language Models (MLLMs) have shown strong performance on public medical benchmarks, yet existing evaluations often remain weak proxies for clinical use, relying on isolated inputs and simplified recognition-style tasks.

By Zixian Su, Hongkai Zhang, Fan Gao, Encheng Su, Taiping Qu, Jingwei Guo, Nan Zhang, Hui Wang, Zhen Zhou, Kairui Bo, Yan Chen, Yue Ren, Shuai Li, Lei Xu, Henggui Zhang
arXiv AI
Jun 26

A Latent ODE Approach to Spatiotemporal Modeling of Cine Cardiac MRI

arXiv:2606. 26718v1 Announce Type: new Abstract: Cardiac magnetic resonance imaging (CMR) captures rich spatiotemporal information about ventricular structure and motion, but conventional risk models use only a few image-derived indices from selected cardiac phases.

By David Br\"uggemann, Ekaterina Krymova, Firat \"Ozdemir, Jochen von Spiczak, Sebastian Kozerke, Samia Mora, Robert Manka, Mathieu Salzmann, Olga V. Demler
arXiv Machine Learning
Jul 20

CardioMeta: Calibrated Multi-Task Prediction of Diabetes, Hypertension, and Cardiovascular Disease Across Population and EHR Data

arXiv:2607. 15721v1 Announce Type: new Abstract: Cardiometabolic diseases remain among the most persistent drivers of preventable morbidity because diabetes, hypertension, and cardiovascular disease frequently co-occur and share metabolic, vascular, demographic, and behavioral determinants.

By S M Asif Hossain, Ruksat Khan Shayoni, M. F. Mridha, Jungpil Shin
arXiv AI
Aug 24

Fine-tuning an ECG Foundation Model to Predict Coronary CT Angiography Outcomes

A multicenter study developed an AI-enabled electrocardiography (AI-ECG) model that predicts vessel-specific hemodynamically significant stenosis using coronary computed tomographic angiography (CCTA) as the reference. The model demonstrated strong discrimination in internal and external cohorts, including normal ECGs, and produced low-, intermediate-, and high-risk strata that correlated with stenosis severity and major adverse cardiovascular events. Calibration, decision curve analyses, and integration with guideline-based pre-test probability showed clinical utility, while waveform and attribution analyses revealed physiologically meaningful ECG features linked to high-risk predictions.

By Yujie Xiao, Qinghao Zhao, Gongzheng Tang, Hao Zhang, Zhuoran Kan, Deyun Zhang, Jun Li, Guangkun Nie, Xiaocheng Fang, Haoyu Wang, Shun Huang, Tong Liu, Jian Liu, Kangyin Chen, Shenda Hong
arXiv AI
Jul 14

A Unified Framework for Comprehensive Cardiac CT Segmentation and Phenotyping: Human-in-the-Loop Data Annotation, Vision Foundation Model Development, Multicenter Evaluation and Clinical Validation

arXiv:2607. 11287v1 Announce Type: cross Abstract: Comprehensive quantification of cardiac structures from computed tomography (CT) remains limited not by data availability but by the scalability of measurements, which makes routine use impractical.

By Pooya Mohammadi Kazaj, Leo Fridolin Weber, Wen Xie, Seyed Amir Ahmad Safavi-Naini, Anselm Stark, Giovanni Baj, Ali Mokhtari, Toshiya Yoshida, Christoph Ryffel, Taishi Okuno, Yoshihiro Akashi, Ronny R. Buechel, Thomas Pilgrim, Waldo Valenzuela, George C. M. Siontis, Xiaowei Xu, Moritz Hundertmark, Stephan Windecker, Christoph Grani, Isaac Shiri
arXiv AI
Jul 2

EchoRisk: A Multicentre Echocardiography Dataset and Benchmark for Cardio-Oncology

arXiv:2607. 01039v1 Announce Type: cross Abstract: Therapy-induced cardiotoxicity is the leading non-oncological cause of treatment interruption in breast cancer patients, yet early, automated risk stratification from routine cardiac imaging remains an unsolved problem.

By Grigorios Kalliatakis, Georgia Karanasiou, Georgios Manikis, Manolis Tsiknakis, Dimitrios Fotiadis, Dorothea Tsekoura, Kalliopi Keramida, Vasileios Bouratzis, Lampros Lakkas, Katerina Naka, Andri Papakonstantinou, Anastasia Constantinidou, Kostas Marias
arXiv AI
Aug 7

Tracing the Heart: An Evidence-Linked Pipeline for Heart-Failure Feature Engineering

arXiv:2608. 06366v1 Announce Type: new Abstract: Electronic health record (EHR) feature engineering is a major bottleneck in clinical research and AI, accounting for 39-45% of data scientists' workload.

By Soorya Ram Shimgekar, Michelle Hu, Dorisa Shehi, Daniel Kang, Roy Ka-Wei Lee, Koustuv Saha, Christian Poellabauer, Christopher Lee, Sajeev Singh, Piyum Zonooz, Navin Kumar, Zeeshan Ahmed, Priyadarshini Kachroo