arXiv AI

KlinikeBench: Evaluating Language Models Beyond Diagnostic Accuracy

arXiv AI
Jul 28

OpenAIs HealthBench in Action: Evaluating an LLM-Based Medical Assistant on Realistic Clinical Queries

arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.

By Sandhanakrishnan Ravichandran, Shivesh Kumar, Rogerio Corga Da Silva, Miguel Romano, Reinhard Berkels, Michiel van der Heijden, Olivier Fail, Valentine Emmanuel Gnanapragasam
arXiv AI
Jul 29

PatientAgentBench: A Benchmark Framework for Evaluating Patient-Facing Health AI Agents

arXiv:2607. 25485v1 Announce Type: new Abstract: Health AI is evolving from answering questions to agentic systems that converse with patients, reason about health records, and act on their behalf.

By Korosh Vatanparvar, Ashutosh Joshi, Maria Xenochristou, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Daniel Lopez-Martinez, Anchal Nema, Ramya Ganesan, Will Kimbrough, Alex Woody, Yadunandana Rao, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
arXiv Computation and Language
Aug 27

MTDiag: A Multi-Turn Diagnostic Dataset Towards Clinically Meaningful LLM Evaluation

MTDiag is a newly released multi-turn diagnostic dialogue dataset designed to evaluate large language models (LLMs) in clinically meaningful ways. It is built from DDXPlus, MIMIC-IV, and AJCR case reports, covering both common emergency department presentations and rare conditions, and normalizes cases into a canonical schema using UMLS concept identifiers and ICD-10 codes. The dataset includes a UserLM‑8B utterance‑generation pipeline and physician‑validated natural‑language utterances, and introduces clinical knowledge‑grounded metrics that go beyond simple diagnostic accuracy for multi‑turn differential diagnosis tasks.

By Pia Chouayfati, Alexander M. Fichtl, Miriam Ansch\"utz, George Doumat, Georg Groh
arXiv AI
Jul 10

MentalHospital: A Virtual Environment for Evaluating Psychiatric Clinical Encounters

arXiv:2607. 08257v1 Announce Type: new Abstract: Large language models (LLMs) have shown strong performance on isolated psychiatric tasks, including dialogue, diagnosis, and treatment planning, yet existing benchmarks rarely simulate complete psychiatric clinical encounters.

By Yuming Yang, Xiao Sun, Yuanwei Zou, Zhengxiao Wu, Yun Chen, Jiang Zhong, Haoyang Zeng, Jingwang Huang, Kaiwen Wei
arXiv AI
Aug 18

DiagnosisArena: Benchmarking Diagnostic Reasoning for Large Language Models

arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.

By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang
arXiv AI
Sep 15

K-Bench: a clinically calibrated benchmark for evaluating large language models in high-risk mental health conversations

arXiv:2609.15855v1 Announce Type: cross Abstract: % !TEX root = ../main.tex People increasingly use large language models (LLMs) for mental health support, yet their safety in evolving, high-risk con...

By Laura M. Vowels, Matthew J. Vowels, Shivali Sharma, Apoorv Jha, Rehnuma Choudhury, Wasseem El Sarraj, Rachel Francois-Walcott, Aruba Hussain, Sarah Ingram, Angela Loulopoulou, Adva Segal, Elena Volkova
arXiv AI
Jun 17

AIPatient Arena: EHR-grounded evaluation of large language models in end-to-end clinical consultation workflows

arXiv:2606. 17474v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly considered for use in clinical consultation tasks, yet most medical evaluations remain static, single-turn, or narrowly outcome-based, limiting their ability to reflect the sequential, uncertain, and interactive nature of real-world care.

By Jiahui Niu, Huizi Yu, Wenkong Wang, Guangxin Dai, Jingxian He, Xiang Li, Zhiying Liang, Xinxin Lin, Kent CY So, Bryan YP Yan, Yun Kwok Wing, Yanqiu Xing, Xin Ma, Lizhou Fan
arXiv Computation and Language
Sep 22

LLMs Anchor on Chief Complaint and Fail to Integrate Evidence in Sequential Clinical Triage

The study evaluates large language models (LLMs) on sequential emergency department triage, where acuity labels are predicted from progressively longer nurse‑patient conversations. Six LLMs were tested at five checkpoints on simulated and physician‑authored dialogues, showing a decline from moderate‑to‑substantial agreement on full records to only fair‑to‑moderate agreement at each checkpoint. The models consistently anchor on chief complaint exchanges and fail to integrate later evidence, yielding low agreement with clinicians (QWK 0.295 vs. 0.887‑0.929) and concentrating predictions on ESI‑2 and ESI‑3. whyItMatters":"The findings reveal that LLMs, despite strong offline performance, cannot reliably handle the sequential nature of real‑time triage, highlighting a critical gap for safe deployment in emergency settings."

By Dipankar Srirag, Haokai Zhao, Ashutosh Kumar, Eleanor Hopper, Michael Dalton, Quoc Dung Nguyen, Aditya Joshi, Salil S. Kanhere, Padmanesan Narasimhan