arXiv AI By Hannes Ill, Rafi Al Attrach, Rajna Fani, Ahram Han, Ryohei Yamamoto, Marlene Louisa Moerig, Dukyong Yoon, Leo Anthony Celi

M4Bench: Evaluating Procedural Specification for Clinical EHR Derivation Agents

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M4Bench is a benchmark comprising 28 clinical derivation tasks across 15 families on MIMIC‑IV and eICU, designed to evaluate whether AI coding agents can reproduce complex procedural specifications for electronic health record (EHR) variable derivation. The study tests agents with and without clinician‑reviewed skill sets, finding that specification completeness drives most performance gains, while generic context or skill format contribute little. The benchmark includes tasks, skills, evaluation code, and sanitized evidence, all released as open‑source.

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