arXiv AI

SeekBrain: An Autonomous Multi-Agent System for Accelerating Neuroscience Discovery

arXiv:2607. 29347v1 Announce Type: cross Abstract: Modern neuroscience relies on integrating multi-scale, multimodal datasets to uncover the neural principles underlying intelligence.

arXiv Computation and Language
Sep 3

NS-Copilot: An LLM-Driven Agent System for Autonomous Neuroscience Analysis

NS-Copilot is a large‑language‑model driven multi‑agent system designed to automate neuroscience data analysis. It integrates domain‑specific pre‑trained models for modalities such as EEG and extracellular spike data, and uses a natural‑language interface to orchestrate agents that plan, generate code, and synthesize results. In benchmarks on Alzheimer’s, Parkinson’s, and working‑memory spike decoding, the system consistently outperformed strong baselines across multiple trials.

By Wuche Liu, Yiran Qiao, Linlin Hou, Rui Yang, Shusen Pu, Song Wang, Jing Ma
arXiv AI
Jun 9

A case study of evaluating AI agents on a neuroscience data-to-discovery pipeline

arXiv:2606. 07718v1 Announce Type: new Abstract: Agentic AI tools offer a promising path to automating software development bottlenecks in scientific research pipelines, particularly for stages that take domain experts days to months to build, where scientists care about correctness and robustness, not implementation details.

By Kai A. Horstmann, Ethan Lin, Alice A. Robie, Jennifer J. Sun, Kristin Branson
arXiv Machine Learning
Sep 21

BrainWideBench: Benchmarking large-scale pretraining and across-animal transfer in multi-region neural recordings

BrainWideBench is a benchmark that evaluates across‑animal transfer on multi‑region neural recordings from 139 mice, covering 276 brain regions. It comprises three task suites—behavior decoding, neural activity prediction, and anatomical organization recovery—to test whether learned representations support diverse downstream objectives. The benchmark shows that while pretraining improves performance over single‑session baselines, current methods vary in transfer ability and none perform uniformly well across all suites, highlighting the challenge of developing general‑purpose neural representations.

By Alexandre Andre, Shivashriganesh P. Mahato, Vinam Arora, Keshav Balaji, Divyansha Lachi, Nanda H. Krishna, Jingyun Xiao, Yizi Zhang, Ximeng Mao, Wenrui Ma, Han Yu, International Brain Laboratory, Daniel Birman, Niccol\`o Bonacchi, Gaelle A. Chapuis, Joana A. Catarino, Felicia Davatolhagh, Mayo Faulkner, Laura Freitas-Silva, Fei Hu, Julia M. Huntenburg, Anup Khanal, In\^es Laranjeira, Petrina Lau, Guido T. Meijer, Nathaniel J. Miska, Jean-Paul Noel, Alejandro Pan-Vazquez, Georg Raiser, Cyrille Rossant, Karolina Z. Socha, Anne E. Urai, Miles J. Wells, Steven J. West, Olivier Winter, Blake Richards, Guillaume Lajoie, Cole Hurwitz, Mehdi Azabou, Matthew R. Whiteway, Liam Paninski, Eva L. Dyer
arXiv AI
Sep 4

NeuroWeaver: An Autonomous Evolutionary Agent for Exploring the Programmatic Space of EEG Analysis Pipelines

NeuroWeaver is an autonomous evolutionary agent that designs EEG analysis pipelines by framing pipeline engineering as a discrete constrained optimization problem solved with large language model–driven code generation. It uses a Domain‑Informed Subspace Initialization to keep the search within neuroscientifically plausible solutions and a Multi‑Objective Evolutionary Optimization to balance performance, novelty, and efficiency. On five diverse benchmarks, NeuroWeaver produces lightweight pipelines that outperform state‑of‑the‑art task‑specific methods and match or exceed large foundation models while using far fewer parameters.

By Guoan Wang, Shihao Yang, Feng Liu
arXiv Machine Learning
Aug 17

BCIJelly: An integrated ecosystem for brain-computer interface research

arXiv:2608. 13576v1 Announce Type: cross Abstract: Brain-computer interface (BCI) research relies on multistage computational pipelines, yet progress remains constrained by fragmented data formats, heterogeneous decoder implementations and hardware-specific deployment toolchains, and researchers lack an integrated workflow.

By Liyuan Han, Xinrui Yang, Tianyu Zheng, Qizhi Yang, Yitao Qin, Liang Chen, Qinglai Wei, Binjie Hong, Xinhe Zhang, Rui Xiong, Yong Gu, Mu-ming Poo, Bo Xu, Chengyu Li, Tielin Zhang
arXiv AI
Jun 4

SciDER: Scientific Data-centric End-to-end Researcher

arXiv:2603. 01421v3 Announce Type: replace Abstract: While large language models accelerate scientific discovery, existing agents face severe limitations in adaptability, domain generalization, and multimodal scalability, often struggling to autonomously process raw, domain-specific experimental data.

By Ke Lin, Owais Aijaz, Yilin Lu, Yiyang Luo, Xuehang Guo, Preslav Nakov
arXiv AI
3d ago

NeuroAI and Beyond: Bridging Between Advances in Neuroscience and Artificial Intelligence

arXiv:2604.18637v3 Announce Type: replace-cross Abstract: Neuroscience and Artificial Intelligence (AI) have made impressive progress in recent years but remain only loosely interconnected. Based on...

By Anthony Zador, Jean-Marc Fellous, Terrence Sejnowski, Gina Adam, James B Aimone, Akwasi Akwaboah, Yiannis Aloimonos, Carmen Amo Alonso, Chiara Bartolozzi, Michael J. Bennington, Michael Berry, Bing W. Brunton, Gert Cauwenberghs, Hillel J. Chiel, Tobi Delbruck, John Doyle, Jason Eshraghian, Ralph Etienne-Cummings, Cornelia Fermuller, Matthew Jacobsen, Ali A. Minai, Barbara Oakley, Alexander G. Ororbia II, Joe Paton, Blake Richards, Yulia Sandamirskaya, Abhronil Sengupta, Shihab Shamma, Michael P. Stryker, Seong Jong Yoo, Steven W. Zucker
arXiv AI
Jun 12

Benchmarking AI Agents for Addressing Scientific Challenges Across Scales

arXiv:2606. 12736v1 Announce Type: new Abstract: AI agents are increasingly being developed to accelerate scientific discovery, yet their practical capabilities in real research settings remain poorly understood.

By Tianyu Liu, Allen Xin Wang, Antonia Panescu, Lisa Xinyi Chen, Wenxin Long, Xinyu Wei, Yueqian Jing, Ziyao Zeng, Jihang Chen, Sihan Jiang, Ziqing Wang, Siyi Gu, Siyu Chen, Xinyang Hu, Haoran Shao, Leqi Xu, Wangjie Zheng, Zhiyuan Cao, Ada Fang, Botao Yu, Kunyang Sun, Rex Ying, Arman Cohan, Qingyu Chen, Lingzhou Xue, Kaize Ding, Yuanqi Du, Wengong Jin, Zhuoran Yang, Marinka Zitnik, James Zou, Hua Xu, Hongyu Zhao