arXiv AI

BrainPilot: Automating Brain Discovery with Agentic Research

arXiv:2607. 15079v1 Announce Type: new Abstract: Understanding the brain increasingly depends on integrating evidence across scales, modalities, and disciplines.

arXiv AI
Aug 21

Bringing analytic rigor to agentic AI for science: The Brain Researcher platform for neuroimaging data analysis

arXiv:2608. 19902v1 Announce Type: new Abstract: AI agents can execute scientific analyses, but an analytic output becomes a defensible claim only after alternatives are weighed and the claim is limited to what the evidence supports.

By Zijiao Chen, Nicholas Lu, Xinhui Li, Jocelyn A. Ricard, Ce Ju, Huan H. Wang, Christian Kindermann, Jeanette A. Mumford, Steven Dillmann, James Kent, Alejandro de la Vega, Sanmi Koyejo, Vince D. Calhoun, Joshua W. Buckholtz, Juan Helen Zhou, Steffen Bollmann, Russell A. Poldrack
arXiv AI
Sep 18

ScientistTwo: Pioneering the Human Knowledge Frontier with Autonomous AI

The paper introduces ScientistTwo, a fully autonomous multi‑agent framework that takes a scientific problem, establishes baselines, generates hypotheses, and coordinates specialized agents to conduct an end‑to‑end discovery cycle without human intervention. It rigorously tests and refines its methods through automated experiments, ablation studies, and a closed‑loop peer‑review engine. Benchmarking against top conferences (ICLR, ICML, NeurIPS) shows that ScientistTwo produces expert‑level, publishable papers and codebases that outperform human state‑of‑the‑art models and receive higher review ratings under automated AI review.

By Jaehyun Nam, Jinsung Yoon, Yanzhou Pan, Yubo Wang, Rui Meng, Parthasarathy Ranganathan, Tomas Pfister
arXiv AI
Jun 9

A case study of evaluating AI agents on a neuroscience data-to-discovery pipeline

arXiv:2606. 07718v1 Announce Type: new Abstract: Agentic AI tools offer a promising path to automating software development bottlenecks in scientific research pipelines, particularly for stages that take domain experts days to months to build, where scientists care about correctness and robustness, not implementation details.

By Kai A. Horstmann, Ethan Lin, Alice A. Robie, Jennifer J. Sun, Kristin Branson
arXiv AI
Jun 12

Benchmarking AI Agents for Addressing Scientific Challenges Across Scales

arXiv:2606. 12736v1 Announce Type: new Abstract: AI agents are increasingly being developed to accelerate scientific discovery, yet their practical capabilities in real research settings remain poorly understood.

By Tianyu Liu, Allen Xin Wang, Antonia Panescu, Lisa Xinyi Chen, Wenxin Long, Xinyu Wei, Yueqian Jing, Ziyao Zeng, Jihang Chen, Sihan Jiang, Ziqing Wang, Siyi Gu, Siyu Chen, Xinyang Hu, Haoran Shao, Leqi Xu, Wangjie Zheng, Zhiyuan Cao, Ada Fang, Botao Yu, Kunyang Sun, Rex Ying, Arman Cohan, Qingyu Chen, Lingzhou Xue, Kaize Ding, Yuanqi Du, Wengong Jin, Zhuoran Yang, Marinka Zitnik, James Zou, Hua Xu, Hongyu Zhao
arXiv AI
Jun 8

Act As a Real Researcher: A Suite of Benchmarks Evaluating Frontier LLMs and Agentic Harnesses in Research Lifecycle

arXiv:2606. 07462v1 Announce Type: new Abstract: As foundation models advance and agent scaffolding becomes increasingly sophisticated, agents have demonstrated remarkable proficiency in complex, long-horizon coding tasks and even autonomous experiment execution.

By Jiayu Wang, Weijiang Lv, Bowen Fu, Jing Fu, Jiayi Song, Lingyu Zhang, Lanxuan Xue, Luodi Chen, Zepeng Xin, Kaiyu Li, Xiangyong Cao
arXiv AI
Jun 26

AgentX: Towards Agent-Driven Self-Iteration of Industrial Recommender Systems

arXiv:2606. 26859v1 Announce Type: new Abstract: Recommendation algorithm iteration is moving from an artisanal, engineer-bound process toward an industrialized research loop, but this transition remains blocked by a structural execution bottleneck: the idea-to-launch cycle still depends on human engineers to generate hypotheses, modify production code, launch A/B experiments, and attribute online results.

By Changxin Lao, Fei Pan, Guozhuang Ma, Han Li, Huihuang Lin, Jijun Shi, Kangzhi Zhao, Kun Gai, Mo Zhou, Qinqin Zhou, Quan Chen, Ruochen Yang, Shifu Bie, Shuang Yang, Shuo Yang, Wenhao Li, Wentao Xie, Xiao Lv, Xuming Wang, Yijun Wang, Yiming Chen, Yusheng Huang, Zhongyuan Wang, Zibo Zhao, Zijie Zhuang, Baoning Xia, Chao Liu, Chaoyi Ma, Chubo He, Dawei Cong, Feng Jiang, Gang Wang, Guilin Xia, Hanwen Xu, Jiahong Xie, Jiahui Qiao, Jian Liang, Jiangfan Yue, Jing Wang, Jinghan Yang, Jinghui Jia, Kan Qin, Lei Wang, Ming Li, Peilin Song, Pengbo Xu, Qiang Luo, Ruiming Tang, Shiyang Liu, Shuxian Jin, Tao Wang, Tao Zhang, Xiang Gao, Xianghan Li, Yingsong Luo, Yiwen Ning, Yongcheng Liu, Yuan Guo, Zhaojie Liu, Zhenkai Cui
arXiv AI
Jul 14

FIRE-Bench: Evaluating AI Agents on the Rediscovery of Scientific Insights

arXiv:2602. 02905v2 Announce Type: replace Abstract: Autonomous agents powered by large language models (LLMs) promise to accelerate scientific discovery end-to-end, but rigorously evaluating their capacity for verifiable discovery remains a central challenge.

By Zhen Wang, Fan Bai, Zhongyan Luo, Jinyan Su, Kaiser Sun, Xinle Yu, Jieyuan Liu, Kun Zhou, Claire Cardie, Mark Dredze, Zhiting Hu, Eric P. Xing
arXiv AI
Jul 17

ReasFlow: Assisting Reasoning-Centric Scientific Discovery in Applied Mathematics via a Knowledge-Based Multi-Agent System

arXiv:2607. 14178v1 Announce Type: new Abstract: Recent advances in Large Language Models have fueled autonomous AI agents capable of tackling complex scientific tasks, yet existing automated research systems remain predominantly focused on empirically driven domains with quantitative benchmarks, leaving theory-driven discovery, particularly in mathematically grounded disciplines requiring rigorous proofs and synthesis of domain knowledge, largely underexplored.

By Yutong He, Daibo Li, Guohong Li, Jiahe Geng, Zhengyang Huang, Can Ren, Zekun Zhang, Yifan Liu, Shuchen Zhu, Hengrui Zhang, Boao Kong, Ming Sun, Shu Li, Chenyi Li, Jiang Hu, Kun Yuan, Zaiwen Wen, Pingwen Zhang