arXiv Machine Learning

Architectural and Regularization Components in Deep Learning Medical Image Registration: Systematic Ablation Study

arXiv Computer Vision
Oct 27

FlexiMIND: Combined Pretrained Vision Features and Local Structure for Training-Free Deformable Medical Image Registration

arXiv:2610.34600v1 Announce Type: new Abstract: Objective. Deformable image registration remains challenging because corresponding anatomy may exhibit different intensity relationships. Hand-crafted...

By Mojtaba Safari, Mingzhe Hu, Shansong Wang, Suyang Xi, Joshua Lorenz, Sean Pitroda, Aytekin Oto, Ralph R. Weichselbaum, Xiaofeng Yang
arXiv Computer Vision
Sep 18

UniReg: Conditional Unified Model for Medical Image Registration

UniReg is a conditional unified model for medical image registration that adapts deformation field estimation based on anatomical priors, registration type constraints, and instance-specific features. It combines the precision of task‑specific learning with the generalization of traditional optimization, enabling effective alignment across diverse CT and MR scenarios within a single framework. Experiments show UniReg outperforms state‑of‑the‑art learning‑based methods in accuracy while providing strong cross‑scenario generalization and reducing training cost and model redundancy.

By Zi Li, Jianpeng Zhang, Tai Ma, Tony C. W. Mok, Yan-Jie Zhou, Zeli Chen, Xianghua Ye, Le Lu, Cheng Chen, Dakai Jin
arXiv Computer Vision
Sep 24

Recursive Uncertainty-Gated Image Registration for Learning-based Algorithms

The paper introduces Recursive Uncertainty-Gated Image Registration (RUGI), an iterative refinement method that updates deformation fields predicted by learning-based registration models using a gating map. Two gating strategies are explored: an uncertainty-based approach and an image residual error approach, both concentrating updates on difficult regions. Experiments on cardiac MRI and echocardiography datasets show that RUGI consistently improves registration accuracy, with the error-gated variant reducing MSE by 27‑37% on pretrained models and lowering ejection fraction estimation errors.

By Clara Rodrigo Gonz\'alez, Oscar Bates, Fu Siong Ng, Meng-Xing Tang
arXiv Computer Vision
Sep 25

When Misalignment Becomes Supervision: Structured Label Noise in Supervised Synthetic CT Generation

The paper examines how residual misalignments from registration procedures introduce structured label noise in supervised synthetic CT (sCT) generation. It shows that voxel‑wise metrics are heavily influenced by the consistency between training and evaluation registrations, and that training with anatomically consistent registrations reduces variability and improves robustness. Introducing a perceptual loss based on a pretrained Segment Anything encoder yields sharper, more anatomically coherent sCT and highlights the need for anatomy‑oriented evaluation.

By Valentin Boussot, Cedric Hemon, Caroline Lafond, Jean-Claude Nunes, Jean-Louis Dillenseger
arXiv AI
Oct 9

ContiLNN: Mitigating Slice Sampling Discontinuity with Liquid Neural Networks for Medical Image Restoration

ContiLNN augments 2‑D medical image restoration backbones with bidirectional closed‑form continuous‑time (Bi‑CfC) modules to model cross‑slice relationships while preserving in‑plane feature extraction. The method uses slice‑index intervals to modulate gates based on local features and hidden states, enabling propagation that adapts to slice‑sampling variations without numerical ODE integration. Across CT denoising, MRI super‑resolution, and PET restoration tasks, ContiLNN outperforms Restore‑RWKV and Bi‑GRU baselines in PSNR, RMSE, latency, and GPU memory usage, demonstrating improved fidelity and data efficiency.

By Jialei He, Enhe Liu, Sifan Song, Pengfei Jin, Jionglong Su, Hongbin Wang, Zhixiang Lu, Yanhao Huang, Anteng Cai, Zhengyong Jiang, Jiaman Ding, S. Kevin Zhou, Jinfeng Wang