arXiv Machine Learning

Why ML-based cough models do not generalize: a systematic cross-dataset evaluation for tuberculosis screening

The study investigates why machine‑learning models for tuberculosis screening based on cough acoustics fail to generalize across datasets. Classical ML and deep‑learning classifiers achieved moderate performance within their own datasets (ROC‑AUC up to 0.755) but performed poorly on external data, often below 0.6. The authors found that audio features were more influenced by recording device and dataset than by TB status, and that device‑diverse training improved transfer while device mismatch degraded it. A clinical‑variable baseline showed more consistent generalization, suggesting acquisition‑specific variability is a stronger driver of poor generalizability than population shift.

arXiv AI
Jun 16

Beyond Classification: A Cough Regression Benchmark for Respiratory Acoustic Foundation Models

arXiv:2606. 15436v1 Announce Type: cross Abstract: Respiratory acoustic foundation models (FMs) excel at cough classification, yet their ability to predict continuous health quantities from cough audio remains largely unexplored, despite the clinical value of passive age, BMI, and disease probability estimation in settings where physical measurements are unavailable.

By Mayur Sanap, Prasanna Desikan, Edgar Lobaton
arXiv AI
Sep 4

LLM4CKD: Large Language Models for Early Stage Chronic Kidney Disease Screening

The paper introduces LLM4CKD, a framework that uses large language models (LLMs) for early chronic kidney disease (CKD) screening without task‑specific training. By employing clinically selected tabular features and structured prompt templates, the authors evaluate LLMs in zero‑shot and few‑shot settings against traditional machine learning, deep learning, and tabular foundation models. Results show that LLMs can match or outperform conventional methods in low‑data scenarios, though their performance varies with model choice and input complexity, highlighting a trade‑off between data efficiency and stability.

By Muhammad Ashad Kabir, Sirajam Munira
arXiv AI
Aug 25

Robust Lightweight Deep Learning Models for Oral Cancer Screening

arXiv:2608.21583v1 Announce Type: new Abstract: Oral cancer is a leading cause of mortality in low-to-middle-income countries, where a shortage of specialists delays diagnosis. While point-of-care sc...

By Siddhant Bharadwaj, Aakash Shedsale, Tejashree Subramanya, Mohd. Azfar, Praveen Birur, Debnath Pal, Shankararama Sharma, Anupama Shetty, Rajesh Sundaresan
arXiv AI
Jun 24

A specialized reasoning large language model for accelerating rare disease diagnosis: a randomized AI physician assistance trial

arXiv:2606. 24510v1 Announce Type: new Abstract: Rare diseases affect millions of individuals worldwide, yet timely diagnosis remains a major public health challenge due to scarcity of specialized clinical expertise.

By Haichao Chen, Songchi Zhou, Zhengyun Zhao, Shikai Hu, Xianghong Jin, Hongwei Ji, Li He, Shuli Li, Yiming Qin, Xin Tan, Runfeng Shi, Yih Chung Tham, Jiaye Zhu, Ye Li, Ye Jin, Longhao Cao, Dawei Li, Honghan Wu, Hongqiu Gu, Guanqiao Li, Tudor Groza, Chunying Li, Dian Zeng, Weihong Yu, Gareth Baynam, Saumya Shekhar Jamuar, Min Shen, Shuyang Zhang, Bin Sheng, Sheng Yu, Tien Yin Wong
arXiv Machine Learning
Jul 28

Long-Tailed Medical Image Classification

arXiv:2607. 23883v1 Announce Type: cross Abstract: In this paper, we examine the difficulties of using standard techniques for medical image classification due to long-tailed distributions (wherein rarer conditions have very few samples) resulting in bias towards diagnosing common diseases and away from rarer diseases.

By Nathanael Ren, Saagar Arya
arXiv AI
Jun 9

AeroSpectra Sentinel: An Auditable LLM Prompt-Chaining Decision-Support Workflow for Acute Asthma Risk Assessment from Respiratory Sounds and Clinical Signals

arXiv:2606. 08247v1 Announce Type: cross Abstract: Acute asthma risk assessment requires rapid interpretation of respiratory sounds, oxygenation, airflow limitation, speech ability, work of breathing, mental status, and response to reliever therapy.

By Aueaphum Aueawatthanaphisut
arXiv Machine Learning
4d ago

Prevalence calibration as shortcut mitigation

Shortcut learning occurs when classifiers rely on spurious correlations instead of true diagnostic features. The authors argue that this is essentially a calibration issue: unconstrained training aligns shortcut groups with their prevalence, causing over‑confidence in one group and under‑confidence in another. They introduce two encoder‑agnostic methods—a regularizer and a post‑hoc recalibration—to equalize prevalence across shortcut groups, achieving significant performance gains on chest‑drain‑pneumothorax benchmarks with both fine‑tuned CNNs and frozen foundation‑model backbones.

By Mohamed Amine Kina, Eike Petersen