The study developed a multimodal ultrasound and clinical data model to predict microvascular invasion (MVI) preoperatively in hepatocellular carcinoma (HCC). Using data from 489 patients across eight centers, the model combined B-mode ultrasound, color Doppler flow imaging, dynamic contrast-enhanced ultrasound, and clinical information, achieving an AUC of 0.8953 in external validation. Dynamic contrast-enhanced ultrasound contributed the most predictive power, while other modalities and clinical data added complementary value.
Background: Microvascular invasion (MVI) predicts recurrence and survival in hepatocellular carcinoma (HCC) but requires postoperative histopathology for diagnosis. We developed and validated a model...
arXiv:2609.26105v1 Announce Type: cross Abstract: Prediction of pathological complete response before neoadjuvant chemotherapy may facilitate more tailored therapeutic planning for breast cancer pati...
arXiv:2607. 12075v1 Announce Type: cross Abstract: Background: Deep learning models can classify thyroid nodules on ultrasound, but reliable clinical decision support also requires calibrated probabilities, uncertainty estimation, and selective referral, particularly under dataset shift.
The study introduces SynerT, a waveform-only hybrid temporal model that uses a causal dilated TCN and dilated recurrent layers to predict early intraoperative acute kidney injury (AKI). Two extensions, SynerT-MM and SynerT-Stack, incorporate hemodynamic summaries, preoperative covariates, and a leakage-safe stacked ensemble to improve discrimination and calibration. Evaluated on the VitalDB database with a strict 60‑minute prediction window, SynerT-Stack achieved the best performance across AUROC, AUPRC, and F1‑max, and demonstrated the greatest net clinical benefit after recalibration.
The study introduces RCC-Align, a cross‑modal contrastive learning framework that aligns paired histopathology whole‑slide images and CT scans to enhance noninvasive grading of clear cell renal cell carcinoma (ccRCC). Using patient‑level five‑fold cross‑validation on TCGA and CPTAC cohorts, RCC‑Align achieved an AUC of 0.601 and AUPRC of 0.599 for low‑ versus high‑grade ccRCC classification, outperforming CT‑only baselines and showing stronger WSI‑CT embedding alignment. The approach relies solely on CT at inference, potentially aiding grading when biopsy is unsafe or limited by tumor heterogeneity.
arXiv:2606. 04365v1 Announce Type: cross Abstract: Radiology reports describe kidney lesions by type, size, enhancement, and attenuation, yet existing 3D methods predict only at the patient or organ level.
The paper introduces the Cross‑Modal Triage Network (CMTN), a multimodal deep‑learning model that fuses a Swin Transformer V2 visual encoder with a PubMedBERT text encoder to perform severity‑based triage, pathology detection, and generate visual explanations for chest radiographs. Trained on 34,639 image‑text pairs from MIMIC‑CXR‑JPG, the CMTN achieves high ordinal agreement with reference labels (QWK = 0.9341) and excellent pathology detection (macro‑AUROC = 0.9970) while operating with 34 ms latency. However, a blinded clinical audit revealed low agreement with expert radiologists (QWK = 0.1399) and only modest spatial‑semantic concordance in heatmaps, underscoring the gap between algorithmic performance and clinical judgment.
arXiv:2608.29348v1 Announce Type: new Abstract: Background: Patient details and acquisition metadata are important for clinical decisions, image quality control, and automated research pipelines, but...
arXiv:2609.26443v1 Announce Type: new Abstract: Recent advances in Artificial Intelligence (AI)-powered Computer-Aided Diagnosis (CAD) systems have substantially improved breast cancer screening, dia...
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
arXiv:2609.26578v1 Announce Type: new Abstract: Accurate preoperative subtype classification of renal cell carcinoma (RCC) from contrast-enhanced CT remains clinically challenging because clear cell...
The paper introduces a multimodal dataset for survival prediction in resected pancreatic ductal adenocarcinoma, comprising 302 patients, 446 H&E whole-slide images, clinicopathological variables, targeted sequencing data for 154 patients, and overall survival outcomes. The authors evaluated fourteen survival‑prediction models, finding that a Ridge Cox regression on numeric clinicopathological variables achieved the highest concordance (≈0.65), while multimodal fusion of image and molecular data reached 0.619. These benchmarks provide a foundation for future research and external validation using this pancreas‑specific dataset.