arXiv AI
Brain2Vec: A Self-Supervised 3D Foundation Model for Structural Brain MRI
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arXiv AI
Jul 21
BrainNext: A General-Purpose Self-Supervised Foundation Model for Brain MRI Analysis
arXiv:2607. 17782v1 Announce Type: cross Abstract: Foundation models pretrained using self-supervised learning have transformed computer vision by learning transferable representations from large-scale unlabeled data.
arXiv AI
Jun 12
BrainDINO: A Brain MRI Foundation Model for Generalizable Clinical Representation Learning
arXiv:2604. 27277v3 Announce Type: replace-cross Abstract: Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data.
arXiv AI
Sep 28
Combining General and Domain-Specific Pretext Tasks for Brain MR Image Segmentation
The paper investigates combining a domain‑specific self‑supervised task—voxel‑level brain age prediction—with a general task—image inpainting—to pretrain models for brain MRI segmentation. A multitask pretraining framework jointly optimizes both objectives, yielding representations that outperform single‑task pretraining and training from scratch on three segmentation benchmarks (multiple sclerosis lesions, ischemic stroke lesions, and cortical structures). The study demonstrates that integrating domain‑specific and general self‑supervised tasks benefits the development of generalizable neuroimaging foundation models.
arXiv AI
Sep 10
Comparative Study of Anatomical and Learned Features in AI Models for Structural Brain MRI
arXiv:2609.06807v1 Announce Type: cross Abstract: In this work, we comprehensively evaluate three popular feature-extraction paradigms in AI-based neuroimaging modeling: (1) computation of anatomical...
arXiv Computer Vision
Sep 24
A generalizable structural brain MRI foundation model built through dual-priority federated pretraining
BrainFedFM is a structural brain MRI foundation model that was federatively pretrained on 164,707 3‑D scans from 42 sites using a dual‑priority approach that emphasizes informative anatomical regions locally and prioritizes site contributions globally. The model outperformed seven baseline models—including four centralized foundation models—across 20 downstream tasks (classification, regression, segmentation), achieving a mean rank of 1.68 and a 50% performance gain, especially in classification and regression and among underrepresented populations. These results demonstrate the model’s generalizability and show that federated pretraining can effectively develop neuroimaging foundation models without pooling raw images.
arXiv Computer Vision
Sep 7
A Generalizable Feature Extractor for Alzheimer's-Related Brain MRI Tasks
The study investigates whether a compact, supervised 3D CNN pretrained for brain‑age prediction can act as a reusable foundation model for various Alzheimer's‑related neuroimaging tasks. By freezing the 7.18 million weights and adding only ~1 % of trainable parameters via Low‑Rank Adaptation, the model achieved high performance across six experiments, including dementia classification, MCI progression prediction, amyloid positivity detection, and volume estimation of hippocampal and white matter hypointensities. The results demonstrate that the pretrained brain‑age model generalizes well to new datasets without retraining, offering a data‑efficient alternative to larger networks.