This study presents a clinically relevant framework for evaluating deep neural networks that segment lymphoma lesions in PET/CT images, addressing gaps such as out‑of‑distribution testing and comparison with expert annotators. Using 611 multi‑institutional cases, the authors assess four networks (ResUNet, SegResNet, DynUNet, SwinUNETR) with lesion‑specific metrics, detection criteria, and metabolic‑characteristic‑based thresholds, finding that models perform best on large, intense lesions. The work also demonstrates that network errors mirror those of physicians, highlighting shared challenges with small, faint lesions.
By Shadab Ahamed, Yixi Xu, Sara Kurkowska, Claire Gowdy, Joo H. O, Ingrid Bloise, Don Wilson, Patrick Martineau, Fran\c{c}ois B\'enard, Fereshteh Yousefirizi, Rahul Dodhia, Juan M. Lavista, William B. Weeks, Carlos F. Uribe, Arman Rahmim
arXiv:2606. 28392v1 Announce Type: cross Abstract: Accurate lesion segmentation in PET/CT is critical for oncology, yet remains challenging because physiologic tracer uptake and artifacts can mimic malignant signal.
By Jiasheng Wang, Tanun Jitwatcharakomol, Piyawadee Jongpradubgiat, Simeng Zhu
arXiv:2608. 07857v1 Announce Type: cross Abstract: Foundation models provide transferable CT representations, but predictions based directly on these embeddings are difficult to interpret.
By Fakrul Islam Tushar, Stephen Adamo, Geoffrey D. Rubin
arXiv:2608. 19666v1 Announce Type: new Abstract: Deep learning-based whole-body PET-CT lesion segmentation can support cancer staging, treatment planning, and response assessment, but generalization is limited by scarce annotations and domain shifts.
By Bashirul Azam Biswas, Amartya Bhattacharya, Biratal Raj Wagle, Matthew E. Maeder, James B. Yu, Indrani Bhattacharya
arXiv:2608.30021v1 Announce Type: cross
Abstract: Errors in radiology reports can adversely affect patient treatment, yet automated report quality assurance remains challenging because errors are oft...
By Hermione Warr, Harry Anthony, Lilli J Freischem, Yasin Ibrahim, Daniel R McGowan, Konstantinos Kamnitsas
Background: Early prediction of distant metastasis (DM) risk in head and neck cancer (HNC) can enable timely interventions that may improve treatment outcomes. Many current machine learning methods rely on prior knowledge of the region of interest such as tumor segmentations, which require expert knowledge, is time-consuming and introduces user-dependent variability.
arXiv:2608.29153v1 Announce Type: new
Abstract: Automated radiological report generation can alleviate clinical workloads and eliminate observer variability. However, standard free-text generation mo...
By Ayush Gupta, Vinkle Srivastav, Prateek Upadhya, Amit Gupta, Krithika Rangarajan, Nicolas Padoy
arXiv:2609.38271v1 Announce Type: new
Abstract: Morphological characteristics such as spiculation and lobulation play an important role in assessing pulmonary nodules on computed tomography (CT), par...
By Namitha Narayanan
MagViT is an interpretable multi‑magnification transformer that classifies breast histopathology images by extracting representations from four BreakHis magnifications (40X, 100X, 200X, 400X) and fusing them with a learnable, scale‑gated mechanism that can mask missing scales. The model selects the most accurate architectural branch at the patient level using five‑fold cross‑validation, achieving high performance on BreakHis (mean image accuracy 0.9191, patient accuracy 0.9643, macro‑F1 0.9042) and demonstrating preliminary cross‑dataset generalization on BUSI and IDC. Grad‑CAM visualizations confirm that the network focuses on diagnostically relevant regions across magnifications.
By Nabil Ashab, Soumit Kumar Kundu, Saif Mahmud Parvez, Shahadat Hossain Sohag, Bidhan Biswas, Nazmus Subha
arXiv:2608. 02615v1 Announce Type: cross Abstract: Cancer diagnosis and characterization require integrating complementary evidence from radiology, pathology, genomics, and clinical metadata.
By Ahnaf Munir, Dannong Wang, Michael W. McDonald, Mubarak Shah, Pegah Khosravi, Yu Tian
arXiv:2606. 07368v1 Announce Type: cross Abstract: Automated mitosis detection is a well-established task in computational pathology.
By Marc Aubreville, Jonas Ammeling, Sweta Banerjee, Viktoria Weiss, Taryn A. Donovan, Robert Klopfleisch, Jiaqi Lv, Shan E Ahmed Raza, Rapha\"el Bourgade, Thomas Walter, Yasemin Topuz, Song\"ul Varl{\i}, Charles-Antoine Collins-Fekete, Zhuoyan Shen, Navya Sri Kelam, Nitin Singhal, Christian Marzahl, Brian Napora, Tengyou Xu, Hongyan Gu, Mario Vento, Gennaro Percannella, Norbert Ropiak, Izabela Wasiak, Jie Xiao, Shaojun Liu, Seungho Choe, April Khademi, Vidushi Walia, Sujatha Kotte, Andrew Broad, Alex Wright, Guillaume Balezo, Esha Sadia Nasir, Mostafa Jahanifar, Yosuke Yamagishi, Shouhei Hanaoka, Mattia Sarno, Francesco Tortorella, Biwen Meng, Jingxin Liu, Sara Krauss, Daniel Hieber, Lavish Ramchandani, Dev Kumar Das, Mieko Ochi, Yuan Bae, Piotr Giedziun, Mateusz Maniewski, Vangala Govindakrishnan Saipradeep, Naveen Sivadasan, Leire Benito-Del-Valle, Adrian Galdran, Kaustubh Atey, Sameer Anand Jha, Adinath Dukre, Imran Razzak, Maxime W. Lafarge, Viktor H. Koelzer, Nils Porsche, Nikolas Stathonikos, Mitko Veta, Dominik Hirling, Zsanett Zs\'ofia Iv\'an, Peter Horvath, Katharina Breininger, Christof A. Bertram
An integrated, web‑based platform has been developed to process diffusion‑weighted imaging (DWI) from MR‑guided linear accelerators and provide structured, literature‑grounded clinical interpretations. The system combines a deep‑learning pipeline for distortion correction, denoising, and IVIM/ADC fitting with a retrieval‑augmented generation (RAG) agent that references a curated knowledge base and traces each statement to its source. Independent expert ratings of nine glioblastoma cases showed high scores for clinical reasoning, citation quality, and overall utility, with a mean rating of 4.65 out of 5.
By Yunxiang Li, Yan Dai, Yen-Peng Liao, Jie Deng, Jill B De Vis, You Zhang