arXiv:2609.38271v1 Announce Type: new
Abstract: Morphological characteristics such as spiculation and lobulation play an important role in assessing pulmonary nodules on computed tomography (CT), par...
By Namitha Narayanan
arXiv:2609.26578v1 Announce Type: new
Abstract: Accurate preoperative subtype classification of renal cell carcinoma (RCC) from contrast-enhanced CT remains clinically challenging because clear cell...
By Yuan Liang, Fangyijie Wang, Kathleen M. Curran, Gu\'enol\'e Silvestre, Sourav Bhattacharjee, Abraham Campbell
Background: Early prediction of distant metastasis (DM) risk in head and neck cancer (HNC) can enable timely interventions that may improve treatment outcomes. Many current machine learning methods rely on prior knowledge of the region of interest such as tumor segmentations, which require expert knowledge, is time-consuming and introduces user-dependent variability.
FedHisto-PAST v2 is a parameter‑efficient, stain‑aware federated learning framework for cross‑site lung histopathology classification, combining a frozen HIBOU‑B foundation model with techniques such as paired‑view prediction, feature consistency, prototype learning, and adaptive aggregation. In a five‑client, non‑IID simulation and an exploratory LungHist700 cohort, the method achieved a Macro‑F1 of 0.7286 and a balanced accuracy of 0.7305, with the prediction‑level consistency component providing the most clear independent benefit. The framework updated only about 1.25% of the model parameters, demonstrating efficient adaptation while acknowledging limitations in privacy guarantees and clinical validation.
By Muhammad Muhtasim Shahriar, M. M. Golam Hafiz, Saad Aloteibi, Mohammad Ali Moni
arXiv:2607. 01001v1 Announce Type: cross Abstract: Radiomics is the established approach for CT-based lung cancer phenotyping, yet comparisons with foundation models rarely isolate contributions of feature extractor, classification head, and segmentation choice, or test cross-cohort robustness.
By Nils Neukirch, Martin Maurer, Nils Strodthoff
arXiv:2607. 12075v1 Announce Type: cross Abstract: Background: Deep learning models can classify thyroid nodules on ultrasound, but reliable clinical decision support also requires calibrated probabilities, uncertainty estimation, and selective referral, particularly under dataset shift.
By Md. Sadibul Hasan Sadib, Md. Mohayminul Mukit, Rahmatul Kabir Rasel Sarker, Tahmid Alam Tamim, Md. Monir Hossain Shimul
Med-AR introduces two autoregressive vision‑language models, Med‑AR‑8B and Med‑AR‑2B, pretrained on structured radiology reports, abnormality‑focused text, and region annotations to address long‑tailed chest X‑ray classification. The models outperform existing contrastive, self‑supervised, and supervised encoders—including Med‑CLIP, CheXFound, EVA‑Base, ARK, and BioViL‑T—across PadChest, MIMIC‑CXR, and CheXpert, achieving higher mean AUROC and AUPRC for head, medium, and tail findings and lower excess area under the risk‑coverage curve. Med‑AR also demonstrates improved selective‑prediction performance, with Med‑AR‑8B raising tail‑label mean AUPRC on MIMIC‑CXR from 0.1033 to 0.1441 and Med‑AR‑2B delivering the strongest discrimination on PadChest.
By Janhavi Prabhu, Sahil, Akshay V, Shivam Shukla, Manoj Tadepalli, Preetham Putha
arXiv:2608. 15004v1 Announce Type: cross Abstract: Lung cancer remains one of the leading causes of cancer-related mortality worldwide, and Computed Tomography (CT) is a primary imaging tool for screening and followup assessment.
By Pramit Dutta, Jenita Manokaran, Richa Mittal, Ryan Appleby, Eranga Ukwatta
arXiv:2609.22281v1 Announce Type: new
Abstract: Foundation models have recently demonstrated strong capabilities across a wide range of medical imaging tasks. However, their performance in structured...
By Benjamin Renoust, Pierre Baudot, Tiffany Foriel, Yousra Haddou, Charles Voyton, Pierre-Henri Siot, Ezequiel Geremia, Danny Francis, Jean-Christophe Brisset, Val\'erie Bourd\`es, Sylvain Bodard, Benoit Huet
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
By Zhi Li (Caris Life Sciences, Irving, TX, United States), Eghbal Amidi (Caris Life Sciences, Irving, TX, United States), Yating Cheng (Caris Life Sciences, Irving, TX, United States), Tyson Dawson (Caris Life Sciences, Irving, TX, United States), Gorkem Can Ates (Caris Life Sciences, Irving, TX, United States), Shuzhen Kuang (Caris Life Sciences, Irving, TX, United States), Norsang Lama (Caris Life Sciences, Irving, TX, United States), Md Ashequr Rahman (Caris Life Sciences, Irving, TX, United States), Zhiying Lu (Caris Life Sciences, Irving, TX, United States), Elisabeth K. Kong (Caris Life Sciences, Irving, TX, United States), Milan Radovich (Caris Life Sciences, Irving, TX, United States), David Spetzler (Caris Life Sciences, Irving, TX, United States), Matthew Oberley (Caris Life Sciences, Irving, TX, United States), George W. Sledge (Caris Life Sciences, Irving, TX, United States), Ming Chen (Caris Life Sciences, Irving, TX, United States)
A specialized large multimodal model, LLaVA‑NeXT, was fine‑tuned on a curated two‑level curriculum of PET/CT image‑conversation pairs to interpret head and neck cancer scans. In external validation across four institutions, the model achieved high ROUGE and similarity scores and outperformed generalist models such as ChatGPT, with primary tumor classification accuracy of 83.14% internally and 69.03% externally. The study demonstrates that domain‑specific LMMs can provide fast, accurate diagnostic support for PET/CT imaging.
By Haengbok Chung, SunGyu Kim, Joo hyun Lee, Sangjin Bae, Min Jeong Cho, Minseok Suh, Jae Sung Lee
arXiv:2608.21571v1 Announce Type: new
Abstract: Lung cancer remains a leading cause of cancer-related mortality worldwide, and early diagnosis is critical for improving survival. However, early-stage...
By Olivera Kotevska, Ian Goethert, Michael McGee, Maria Mahbub, Sean R. Wilkinson, Rowena Yip, Myvizhi Esai Selvan, Zeynep H. Gumus, Claudia Henschke, Robert J. Klein, Providencia Morales, Samuel M Aguayo, Ioana Danciu, Mayanka Chandrashekar