arXiv:2607. 05880v1 Announce Type: cross Abstract: Imaging demand is growing faster than the radiology workforce can expand, and reporting backlogs cannot be resolved through training and recruitment alone.
By Suneeta Mall, Vladimir Nekrasov, Ashnil Kumar, Sajith Karunasena, Aiden Nibali, Alix Bird, Mateo Diaz Shine, Jarrel Seah
Med-AR introduces two autoregressive vision‑language models, Med‑AR‑8B and Med‑AR‑2B, pretrained on structured radiology reports, abnormality‑focused text, and region annotations to address long‑tailed chest X‑ray classification. The models outperform existing contrastive, self‑supervised, and supervised encoders—including Med‑CLIP, CheXFound, EVA‑Base, ARK, and BioViL‑T—across PadChest, MIMIC‑CXR, and CheXpert, achieving higher mean AUROC and AUPRC for head, medium, and tail findings and lower excess area under the risk‑coverage curve. Med‑AR also demonstrates improved selective‑prediction performance, with Med‑AR‑8B raising tail‑label mean AUPRC on MIMIC‑CXR from 0.1033 to 0.1441 and Med‑AR‑2B delivering the strongest discrimination on PadChest.
By Janhavi Prabhu, Sahil, Akshay V, Shivam Shukla, Manoj Tadepalli, Preetham Putha
arXiv:2608. 07857v1 Announce Type: cross Abstract: Foundation models provide transferable CT representations, but predictions based directly on these embeddings are difficult to interpret.
By Fakrul Islam Tushar, Stephen Adamo, Geoffrey D. Rubin
WILSON is a vision–language foundation model that represents whole‑slide images and multi‑slide patient cases as single multi‑magnification composite images. Trained on about 189,000 Mayo Clinic slides covering 42 organs and 829 diagnostic entities, it outperforms dedicated case‑level models on internal cohorts and matches slide‑level models while using far less compute. Fine‑tuning on triple‑negative breast cancer data improves histologic subtyping and lymphocyte grading, and the model retrieves diagnostic text with high recall and generates captions closer to report references than prior methods.
By Saghir Alfasly, Wataru Uegami, Sobhan Hemati, Wenchao Han, Xiaojia Tang, Kevin Thompson, Daniel Stone, Ghazal Alabtah, Saba Yasir, Michael R. Lucas, Eric W. Klee, Cheryl L. Willman, Judy C. Boughey, Matthew P. Goetz, Krishna R. Kalari, H. R. Tizhoosh
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
By Zhi Li (Caris Life Sciences, Irving, TX, United States), Eghbal Amidi (Caris Life Sciences, Irving, TX, United States), Yating Cheng (Caris Life Sciences, Irving, TX, United States), Tyson Dawson (Caris Life Sciences, Irving, TX, United States), Gorkem Can Ates (Caris Life Sciences, Irving, TX, United States), Shuzhen Kuang (Caris Life Sciences, Irving, TX, United States), Norsang Lama (Caris Life Sciences, Irving, TX, United States), Md Ashequr Rahman (Caris Life Sciences, Irving, TX, United States), Zhiying Lu (Caris Life Sciences, Irving, TX, United States), Elisabeth K. Kong (Caris Life Sciences, Irving, TX, United States), Milan Radovich (Caris Life Sciences, Irving, TX, United States), David Spetzler (Caris Life Sciences, Irving, TX, United States), Matthew Oberley (Caris Life Sciences, Irving, TX, United States), George W. Sledge (Caris Life Sciences, Irving, TX, United States), Ming Chen (Caris Life Sciences, Irving, TX, United States)
The study investigates whether pathology foundation models can enable training‑free, content‑based retrieval of similar cases from digitized archives of salivary gland tumors. Using a region of interest from a whole slide image, the models retrieve morphologically similar cases and their ICD‑O codes without task‑specific training. Evaluation on 137 cases across 12 morphology categories shows that Atlas2 achieves the highest retrieval accuracy, with macro‑averaged F1 scores ranging from 69.0% to 76.6% across models.
By Maximilian J. Roesel, Niklas Kiermeyer, Philipp Keyl, Frederick Klauschen
arXiv:2608. 00147v1 Announce Type: cross Abstract: Vision-language pretraining learns rich medical image representations from radiology reports, but previous model variants commonly operate within a single shared embedding space, so concept-level structure and interpretability must be recovered post hoc, limiting model transparency and, hence, clinical utility.
By Fabian Drexel, Marlene Fritzsche, Era Stambollxhiu, Miriam Kumpf, Lena Schmitzer, Lea Schumann, Jannik Kahmann, Friedrich Puttkammer, Johannes Moll, Jannik L\"ubberstedt, Zeineb Ben Chaaben, Anirudh Narayanan, Cosmin I. Bercea, Sebastian Ziegelmayer, Marcus R. Makowski, Daniel Rueckert, Lisa C. Adams, Keno K. Bressem
arXiv:2606. 28980v1 Announce Type: cross Abstract: Ovarian cancer is frequently diagnosed at an advanced stage, making preoperative contrast-enhanced computed tomography (CT) central to staging and surgical planning; yet the scarcity of annotated imaging data, compounded by privacy regulations, limits the development of generalizable computational models in this domain.
By Francesca Pia Panaccione, Eugenio Lomurno, Francesca Fati, Carlotta Pecchiari, Marina Rosanu, Luigi De Vitis, Lucia Ribero, Gabriella Schivardi, Giovanni Damiano Aletti, Nicoletta Colombo, Maria Francesca Spadea, Francesco Multinu, Matteo Matteucci, Elena De Momi
Lumen is a pathology vision‑language model that aligns frozen unimodal foundation models (Virchow2 and BioMedBERT) using rank‑4 adapters and projection heads, training only 0.40% of the total parameters on the QUILT‑1M corpus. It achieves the highest mean chance‑corrected balanced accuracy (0.546) across nine zero‑shot patch benchmarks and demonstrates strong performance on lymph‑node metastasis detection, with AUROC scores of 0.964 internally and 0.955 externally. While it ranks third in cross‑modal retrieval, Lumen’s low‑parameter training yields competitive results at both patch and slide levels.
By Kiarash Tajbakhsh, Abdelrahman Faqieh, Michael Jopiti, Javier Garcia-Baroja, Philipp Zens, Branislav Zagrapan, Yuri Tolkach, Martin D. Berger, Aurel Perren, Bastian Dislich, Inti Zlobec, Amjad Khan
arXiv:2607. 03466v1 Announce Type: cross Abstract: This study aims to predict Tumor, Node, and Metastasis (TNM) stage labels independently, with the Cancer Genome Atlas (TCGA) pathology report as the sixth shared task of SMM4H-HeaRD 2026.
By Joseph Itopa Abubakar, Jorge Jarme, Favour Igwezeke, Mary Adewunmi
The paper introduces Report Supervision (R‑Super), a framework that uses radiology reports to supervise tumor segmentation models. By incorporating loss functions that align segmentation outputs with report‑derived tumor counts, sizes, and locations, R‑Super improves detection and segmentation performance. Experiments on kidney and pancreatic tumors show up to a 15% increase in F1‑Score and DSC compared to mask‑only training, outperforming methods like CLIP and multi‑task learning.
By Pedro R. A. S. Bassia, Wenxuan Li, Jakob Wasserthal, Jieneng Chen, Xinze Zhou, Zheren Zhu, Chuntung Zhuanga, Sergio Decherchi, Andrea Cavalli, Kang Wang, Yang Yang, Alan Yuille, Zongwei Zhou
arXiv:2607. 19261v1 Announce Type: cross Abstract: Whole-slide image (WSI) diagnosis requires identifying diagnostically relevant regions, examining them across magnifications, and integrating multi-scale evidence.
By Dankai Liao, Tianyi Zhang, Yufeng Wu, Xinyue Zhang, Qiaochu Xue, Zeyu Liu, Dachun Zhao, Linghan Cai, Yueming Jin