arXiv:2601. 05148v2 Announce Type: replace-cross Abstract: Pathology foundation models substantially advanced the possibilities in computational pathology --- yet tradeoffs in terms of performance, robustness, and computational requirements remained, which limited their clinical deployment.
By Maximilian Alber, Timo Milbich, Alexandra Carpen-Amarie, Stephan Tietz, Jonas Dippel, Lukas Muttenthaler, Beatriz Perez Cancer, Alessandro Benetti, Panos Korfiatis, Elias Eulig, J\'er\^ome L\"uscher, Jiasen Wu, Sayed Abid Hashimi, Gabriel Dernbach, Simon Schallenberg, Neelay Shah, Moritz Kr\"ugener, Aniruddh Jammoria, Jake Matras, Patrick Duffy, Matt Redlon, Philipp Jurmeister, David Horst, Lukas Ruff, Klaus-Robert M\"uller, Frederick Klauschen, Andrew Norgan
arXiv:2607. 22861v1 Announce Type: cross Abstract: Pathology foundation models (FMs) produce powerful tile-level representations which remain sensitive to scanner and staining variability, undermining deployment across laboratories.
By Alexandre Filiot, Oskar Thaeter, Benoit Schmauch, Lionel Guillou
arXiv:2608. 03990v1 Announce Type: new Abstract: Synthetic histopathology image generation has emerged as an approach that may address data scarcity in computational pathology, yet current evaluation methodologies may not fully assess synthetic data quality for medical applications.
By Seyed Kahaki, Shijie Li, Weijie Chen, Nicholas Petrick
arXiv:2607. 25497v2 Announce Type: replace-cross Abstract: Pathology foundation models encode non-biological variation introduced by tissue preparation, staining and scanning, enabling shortcut learning that undermines generalisation across institutions.
By Cl\'ement Grisi, Jeroen van der Laak, Geert Litjens
arXiv:2607. 25497v1 Announce Type: cross Abstract: Pathology foundation models are approaching clinical deployment, yet remain vulnerable to systematic non-biological variation across centres.
By Cl\'ement Grisi, Jeroen van der Laak, Geert Litjens
arXiv:2601. 08127v2 Announce Type: replace-cross Abstract: Expert-annotated training data remains the critical bottleneck for AI in histopathology, particularly for rare pathologies where even dozens of cases may be unavailable.
By Mohamad Koohi-Moghadam, Mohammad-Ali Nikouei Mahani, Rex K. H. Au-Yeung, Raymond Yu O, Monalyn Marabi, Piyapharom Intarawichian, Fabian Z. X. Lean, Andrew Ferguson, Kyongtae Tyler Bae
arXiv:2608. 05960v1 Announce Type: cross Abstract: Routine CT interpretation is inherently comprehensive, capturing incidental findings across the entire scan volume.
By Maulik Chevli, Johannes Brandt, Rickmer Braren, Daniel Rueckert, Philip M\"uller
arXiv:2606. 06983v1 Announce Type: cross Abstract: Computational pathology requires visual representations that transfer across diverse clinical endpoints and remain robust to variation in magnification, staining, scanner type, slide preparation, and input resolution.
By Bokai Zhao, Yiyang Zhang, Long Bai, Tai Ma, Hanqing Chao, Minfeng Xu
arXiv:2606. 00491v1 Announce Type: cross Abstract: Deep learning-based CT segmentation systems often achieve high accuracy on clean benchmark images, but their performance may degrade under heterogeneous clinical imaging conditions such as noise, resolution loss, contrast variation, intensity shift, and artifacts.
By CholMin Kang, Jonghyun Chung, Amanpreet Kaurb, Nagesh Gulkotwarb, Arthi Sivasankaranb
arXiv:2606. 07590v1 Announce Type: cross Abstract: Pathology foundation models are pretrained on large streams of WSI-derived patches, while supervision during data construction is often slide-level, sparse, or heterogeneous.
By Mingyi He, Xinyi Guo, Xitong Ling, Weiming Chen, Jiawen Li, Lianghui Zhu, Minxi Ouyang, Mingxi Fu, Yizhi Wang, Tian Guan
arXiv:2511. 05150v2 Announce Type: replace-cross Abstract: Molecular biomarker testing in pathology is often costly and tissue-consuming, limiting scalable clinical deployment.
By Jingsong Liu, Han Li, Zhengyang Xu, Franz-Leonard Klaus, Fabian St\"ogbauer, Shihui Zu, Weiwei Zhou, Atsuko Kasajima, Felix Schicktanz, Alexander Muckenhuber, Julius Shakhtour, Jiale Yu, Tiannan Zheng, Xun Ma, Maggie Wang, Christian Grashei, Bao Li, Guiyang Jiang, Hongming Xu, Shaohua Kevin Zhou, Nassir Navab, Peter J. Sch\"uffler
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
By Jingyu Hu, Giuseppe Tripodi, Reed Naidoo, Sarah F. McGough, Tapabrata Chakraborti