arXiv AI

Representation Bias, Correction Transfer, and Resolution Sensitivity in Three-Dimensional Mitochondrial Morphometry

arXiv AI
Sep 18

Bridging Modalities on the Cortex: Surface-based MRI to PET Translation with a Diffusion Bridge

The paper introduces DB‑SUiT, a surface‑based diffusion bridge that translates cortical MRI to PET images directly on the cortical manifold. It employs a conditional spherical U‑shaped vision Transformer to capture multi‑scale surface features and long‑range dependencies while incorporating demographic and subcortical information. Evaluations on two dementia datasets show that the synthesized PET surfaces outperform MRI and PET volumes in automated classification and achieve high diagnostic accuracy in a blinded reader study.

By Yitong Li, Alexandra Samoylova, Fabian Bongratz, Timo Grimmer, Dennis M. Hedderich, Igor Yakushev, Christian Wachinger
arXiv Machine Learning
Aug 11

Beyond Isotropic Assumptions: Continuity-Constrained Segmentation and GPU Morphometry for Nanoscale GBM Analysis

arXiv:2608. 07575v1 Announce Type: cross Abstract: Confocal microscopy of optically cleared and swelled tissue resolves complex biological structures in 3D, but such acquisitions are highly anisotropic: along the under-sampled axial direction the structure can appear discontinuous, hampering reconstruction and automated quantitative analysis.

By Arash Fatehi, Robin Ebbestad, Linus Butt, Hans Blom, Sigrid Lundberg, Hannes Olauson, Hjalmar Brismar, David Unnersj\"o-Jess, Thomas Benzing, Katarzyna Bozek
arXiv Machine Learning
Aug 10

Recovering Lesion Parameters from Aphasic Picture Naming Error Profiles in Large Language Models

arXiv:2608. 06429v1 Announce Type: cross Abstract: Interpretability methods for large language models (LLMs) describe internal state but do not directly test whether that state is causally sufficient to produce the observed behavior.

By Yong Yang, Roger Newman-Norlund, Xiang Guan, Saeed Ahmadi, Regan Willis, Nadra Salman, Kalil Warren, Sophie Arheix-Parras, Srihari Nelakuditi, Leonardo Bonilha, Christopher Rorden, Rutvik H. Desai, Julius Fridriksson
arXiv Computer Vision
Sep 23

Uncertainty-Aware 3D Residual Wavelet Diffusion for Ultra Low-Field MRI Super-Resolution

The paper introduces a 3D residual wavelet diffusion model for super‑resolving ultra low‑field MRI scans. By using a lossless wavelet reparameterisation, residual shifting, and domain randomisation, the method fits whole‑brain data on a single GPU, speeds up sampling, and generalises across scanners. It achieves volumetric accuracy comparable to leading regression approaches while producing per‑voxel uncertainty maps that reveal under‑determined regions and preserves disease‑relevant atrophy in cognitively impaired subjects.

By Rui W. Yeow, Millie Beament, Fred Dick, Raha Razin, Martina Bocchetta, David L. Thomas, Henry F. J. Tregidgo, Daniel C. Alexander, James H. Cole
arXiv AI
Jun 30

ReMAP-PET: Beyond Visual Understanding -- Learning Region-Guided Metabolic Alignment Semantics from Brain PET

arXiv:2606. 29577v1 Announce Type: cross Abstract: Positron Emission Tomography (PET) reveals brain metabolism and is clinically central to neurodegenerative disease assessment, yet existing 3D brain foundation models treat PET as generic volumetric data, missing the structured regional metabolic information that distinguishes it from structural neuroimaging.

By Dasen Dai, Yanteng Zhang, Shuoqi Li, Yuxiang Wei, Hongjie Yu, Qingxin Zhang, Qizhen Lan, Jagath C. Rajapakse, Vince D. Calhoun
arXiv Computer Vision
Sep 16

Anatomy-Change-Aware Bidirectional Selective State-Space Memory for Clinically Deployed Thoracic Radiotherapy Auto-Contouring

The paper introduces DAMM‑Net++, a 2.5D neural network for thoracic organ‑at‑risk and target volume segmentation that tackles inter‑slice surface incoherence, small low‑contrast target failure, and lack of per‑case reliability signals. Its core is an anatomy‑change‑aware bidirectional selective state‑space memory that propagates context across axial slices, complemented by a boundary‑aware decoder and an uncertainty head for calibrated per‑voxel confidence. Evaluations on 2,146 patients, an external cohort, and a reader study show high Dice scores (0.955), low HD95 (3.78 mm), significant time savings (75‑80 %) for clinicians, and improved junior‑reader performance, with the system fully integrated into a clinical workflow.

By Galib Ahmed, Istiak Ahmed, Aritra Islam Saswato, Asib Mostakim Fony, Kazi Shahriar Sanjid, Md. Tanzim Hossain, Md. Anwarul Islam, Md. Nishan Khan, Md. Misbah Khan, Labiba Faiza Karim, Jobaer Rahman, S M Hasibul Hoque, Rahnuma Shahrin Rista, Kamruzzaman Rumman, Md Arifur Rahman, Syed Md. Akram Hussain, Mohammad Ashrafuzzaman Khan, M. Monir Uddin