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arXiv AI

Bridging Modalities on the Cortex: Surface-based MRI to PET Translation with a Diffusion Bridge

The paper introduces DB‑SUiT, a surface‑based diffusion bridge that translates cortical MRI to PET images directly on the cortical manifold. It employs a conditional spherical U‑shaped vision Transformer to capture multi‑scale surface features and long‑range dependencies while incorporating demographic and subcortical information. Evaluations on two dementia datasets show that the synthesized PET surfaces outperform MRI and PET volumes in automated classification and achieve high diagnostic accuracy in a blinded reader study.

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arXiv Computer Vision
Aug 31

3D MRI-Based Alzheimer's Disease Classification Using Multi-Modal 3D CNN with Leakage-Aware Subject-Level Evaluation

The paper presents a multimodal 3D convolutional neural network that classifies Alzheimer’s disease using raw OASIS 1 MRI volumes. It fuses structural T1 images with gray matter, white matter, and cerebrospinal fluid probability maps to capture complementary neuroanatomical information. Evaluated with 5‑fold subject‑level cross‑validation, the model achieves a mean accuracy of 72.34 % and an ROC AUC of 0.7781, with GradCAM visualizations highlighting anatomically relevant regions such as the medial temporal lobe and ventricles.

By Md Sifat, Sania Akter, Akif Islam, Md. Ekramul Hamid, Abu Saleh Musa Miah, Najmul Hassan, Md Abdur Rahim, Jungpil Shin
computer-visionmultimodalbenchmarks
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arXiv Machine Learning
Jun 18

Structural MRI Synthesis for Alzheimer's Disease via Conditional Diffusion on Anatomical Masks

arXiv:2606. 18354v1 Announce Type: cross Abstract: Recent advances in generative machine learning models have significantly improved medical imaging, offering promising solutions for data augmentation, privacy preservation, and improved model generalization.

By Muge Zhang, Muhammad Ali Khaliq, Jamal Alsakran, Byeong Kil Lee, Jeeho Ryoo
diffusioncomputer-visionsafety
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arXiv AI
Jul 9

Heterogeneity-Adaptive Diffusion Schrodinger Bridge for PET-Guided Whole-Body MRI Translation

arXiv:2607. 07401v1 Announce Type: cross Abstract: While whole-body multimodal medical imaging scanners have been increasingly recognized for more effective medical applications, the excessive long acquisition time in PET-MR scanning is a major obstacle in more efficient clinical practice.

By Chengbo Wang, Jiacheng Yu, Linjie Bian, Ming Qi, Xiaosheng Liu, Tongtong Che, Jichang Zhang, Shuyu Li, Shaoli Song, Xiuying Wang
llmsragdiffusionmultimodal
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arXiv Machine Learning
Jun 16

Lesion-DDPM: Lesion-Enhanced 3D Diffusion for MS MRI Synthesis

arXiv:2606. 15457v1 Announce Type: cross Abstract: 3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns.

By Weidong Zhang, Yongchan Jung, Shafayat Mowla Anik, Furen Xiao, Vasudevan Janarthanan, Enkhzaya Chuluunbaatar, Byeong Kil Lee, Jeeho Ryoo
diffusioncomputer-visionbenchmarks
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arXiv Computer Vision
5d ago

Cross-Modality Structural Guidance in 3D Latent Diffusion for Robust FLAIR Super-Resolution

The paper introduces MR‑DiffuSR, a 3‑D latent diffusion framework that uses high‑resolution T1w structural priors to guide super‑resolution of thick‑slice FLAIR MRI scans. By applying cross‑modality structural swin attention and a mixed‑scale degradation strategy, the method avoids hallucinations and remains robust across varying slice thicknesses. On ADNI datasets, MR‑DiffuSR outperforms CNN and 2‑D diffusion baselines, achieving high PSNR, SSIM, and low LPIPS, and maintains strong white‑matter hyperintensity segmentation performance even at 7 mm equivalent slice thickness.

By Haoyu Lan, Jiazhen Zhang, John Onofrey, Bino Varghese, Nasim Sheikh-Bahaei, Arthur W. Toga, Jeiran Choupan
diffusioncomputer-visionsafety
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arXiv Computer Vision
Sep 15

DTI-Guided Volumetric Spherical Harmonics Regression for Single-to-Multi-Shell dMRI Synthesis

arXiv:2609.14312v1 Announce Type: new Abstract: Multi-shell diffusion MRI (dMRI) unlocks more expressive microstructural modeling than single-shell scans, yet its longer acquisition time hinders depl...

By Binghua Li, Christina Andica, Tong Liang, Ziqing Chang, Chao Li, Wataru Uchida, Kaito Takabayashi, Qibin Zhao, Toshihisa Tanaka, Zhe Sun, Shigeki Aoki
diffusion
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arXiv Computer Vision
Sep 23

Uncertainty-Aware 3D Residual Wavelet Diffusion for Ultra Low-Field MRI Super-Resolution

The paper introduces a 3D residual wavelet diffusion model for super‑resolving ultra low‑field MRI scans. By using a lossless wavelet reparameterisation, residual shifting, and domain randomisation, the method fits whole‑brain data on a single GPU, speeds up sampling, and generalises across scanners. It achieves volumetric accuracy comparable to leading regression approaches while producing per‑voxel uncertainty maps that reveal under‑determined regions and preserves disease‑relevant atrophy in cognitively impaired subjects.

By Rui W. Yeow, Millie Beament, Fred Dick, Raha Razin, Martina Bocchetta, David L. Thomas, Henry F. J. Tregidgo, Daniel C. Alexander, James H. Cole
diffusioncomputer-vision
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