The paper introduces DINO-Med, a patch‑based framework that adapts natural‑image foundation models to multi‑modal medical imaging, specifically for liver fibrosis staging. It processes raw multimodal scans through training‑free registration, automated localization, and mask‑filtered patch extraction, then aggregates patch‑level insights into subject‑level diagnostics. Using the CARE 2025 Liver Track 4 cohort, the DINOv3‑based approach achieved the highest classification accuracy (78.4% for mild fibrosis and 75.8% for cirrhosis) compared to other feature representations.
arXiv:2610.18243v1 Announce Type: cross
Abstract: Given the growing global burden of liver tumors and diffuse liver diseases, non-contrast computed tomography (NCCT) is increasingly used for opportun...
By Hao Zhang, Yi Huang, Wei Liu, Yuan Gao, Zeju Li, Xu Han, Yu Shi, Ling Zhang, Ke Yan
LiFUSE introduces a unified frequency‑spatial self‑supervised pretraining framework for liver disease analysis on non‑contrast CT scans. The method employs a frequency branch that uses random band‑stop masking and spectrum reconstruction, and a spatial branch that performs hybrid‑granularity masked volumetric reconstruction, with a cross‑domain consistency scheme to fuse the two branches. Experiments on three clinical tasks and a public transfer setting demonstrate that LiFUSE consistently outperforms strong baselines, indicating its potential to enhance liver disease screening using low‑contrast NCCT images.
arXiv:2607. 10358v1 Announce Type: cross Abstract: Foundation models are increasingly used as image feature extractors for mammography, but their robustness under external domain shift remains unclear.
By Giang Nguyen, Raghav Mehta, Emma A. M. Stanley, Tian Xia, Thi Hao Nguyen, Hieu Pham, Ben Glocker
arXiv:2409.16183v2 Announce Type: replace
Abstract: Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in m...
By Xiaohong Liu, Guoxing Yang, Yulin Luo, Jiaji Mao, Xiang Zhang, Haibo Wang, Zhiyang He, Ming Gao, Shanghang Zhang, Jun Shen, Guangyu Wang
The paper introduces the FAPT-M Dataset, a pathology‑confirmed multimodal collection of 910 breast patients that includes ultrasound images, structured clinical attributes, and diagnostic descriptions. It proposes a clinically guided multimodal framework that fuses DenseNet visual encoding, CLIP‑inspired text encoding, and lightweight clinical encoding, enhanced by clinical‑conditioned adaptive modulation, cross‑modal Transformer fusion, and dual‑path representation learning. The method achieves 77.64% accuracy, 73.38% F1‑score, and 89.74% AUC, outperforming CNN, Transformer, and vision‑language baselines, and demonstrates the value of three‑modality fusion through ablation and class‑balanced studies.
By Chuxi Nan, Di Wu, Hongming Guo, Ning Cao, Xiaohui Zhu, Zhaoting Shi, Jiawei Li
arXiv:2609.14010v1 Announce Type: new
Abstract: We present CirrGuide, a deep cascaded framework for cirrhotic liver segmentation and severity classification. Cirrhosis causes progressive structural c...
By Muntaqim Ahmed Raju, Ruizhe Ma
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
By Zhi Li (Caris Life Sciences, Irving, TX, United States), Eghbal Amidi (Caris Life Sciences, Irving, TX, United States), Yating Cheng (Caris Life Sciences, Irving, TX, United States), Tyson Dawson (Caris Life Sciences, Irving, TX, United States), Gorkem Can Ates (Caris Life Sciences, Irving, TX, United States), Shuzhen Kuang (Caris Life Sciences, Irving, TX, United States), Norsang Lama (Caris Life Sciences, Irving, TX, United States), Md Ashequr Rahman (Caris Life Sciences, Irving, TX, United States), Zhiying Lu (Caris Life Sciences, Irving, TX, United States), Elisabeth K. Kong (Caris Life Sciences, Irving, TX, United States), Milan Radovich (Caris Life Sciences, Irving, TX, United States), David Spetzler (Caris Life Sciences, Irving, TX, United States), Matthew Oberley (Caris Life Sciences, Irving, TX, United States), George W. Sledge (Caris Life Sciences, Irving, TX, United States), Ming Chen (Caris Life Sciences, Irving, TX, United States)
arXiv:2608. 13939v1 Announce Type: cross Abstract: Ultrasound is the primary imaging modality for assessing thyroid nodules, and the ACR TI-RADS framework standardizes diagnosis through five ultrasound feature categories that are aggregated into five risk levels (TR1-TR5).
By Bingxin Yu, Xueli Wang, Jerry Zhou, Wenyan Wang, Li Wen, Lan Huang, Xin Feng, Fengfeng Zhou, Kewei Li
SCOUT is a concept‑grounded multimodal transformer that generates whole‑slide pathology reports by integrating local histological patterns, whole‑slide context, and expert‑curated diagnostic concepts. It uses evolving visual representations and recursively updated slide‑ and concept‑conditioned representations, with separate attention pathways during decoding that are fused adaptively for each token. Evaluated on TCGA‑BRCA, HistAI, and REG‑2025, SCOUT outperformed existing methods, improving BLEU, METEOR, and ROUGE‑L scores and raising the Clinical Report Quality Score on REG‑2025.
By Suryakant Singh, Saarthak Kapse, Joel Saltz, Prateek Prasanna
arXiv:2606. 16991v1 Announce Type: cross Abstract: Multiphasic contrast-enhanced CT (CECT) is widely used for abdominal lesion characterization, yet it carries inherent risks of contrast-induced nephropathy, escalates acquisition burden, and heavily contributes to radiologist workload.
By Mariam Elbakry, Aliaa Sayed Sheha, Salma Hassan Tantawy, Aya Yassin, Concetto Spampinato, Karim Lekadir, Xiaomeng Li, Marawan Elbatel
nnFoundation introduces complementary convolutional and transformer-based 3D foundation models for radiology, trained on 2.1 million CT, MRI, and PET volumes from 125 datasets. The models are evaluated on 108 tasks—including segmentation, detection, classification, report generation, and image retrieval—under domain shift, low-data, and low-compute scenarios, consistently outperforming prior 3D foundation models and training from scratch. Performance varies by task type, with convolutional models excelling at spatially localized tasks and transformer models at global semantic reasoning, and dynamic alignment with dataset characteristics further enhances transferability.
By Constantin Ulrich Harsy, Tassilo Wald, Karol Gotkowski, Yannick Kirchhoff, Marcel Knopp, Maximilian Rokuss, Elisa Stegmeier, Philipp Schader, Dasha Trofimova, Raphael Stock, Kim-Celine Kahl, Stephen Schaumann, Selen Erkan, David Zimmerer, Stefan Denner, Moritz Langenberg, Sebastian Ziegler, Katharina Eckstein, Maximilian Fischer, Jonathan Suprijadi, B\'alint Kov\'acs, Benjamin Hamm, Anand Deshpande, Dimitrios Bounias, Nico Disch, Shuhan Xiao, Jessica K\"achele, Jan Sellner, Rajesh Baidya, Jeremias Traub, Lars Kr\"amer, Maximilian Zenk, Tim R\"adsch, Stefan Dvoretskii, Robin Peretzke, Jonathan Deissler, Alexandra Ertl, Partha Ghosh, Kris Dreher, Stefan Dinkelacker, Annika Reinke, Evangelia Christodoulou, Numan Saeed, Yoland Savriama, Santiago Estrada, David K\"ugler, Laura Alexandra Daza Barragan, Cristina Isabel Gonzalez Osorio, Jan Peeken, Michael Baumgartner, Marvin Teichmann, Guillaume Chabin, Matthias Kirchler, Valentin Koch, for the ALFA study, Markus Hohenhaus, Dimitri Koslov, Nina Decker, Mohammad Yaqub, Arnd Heuser, Martin Reuter, Julia A. Schnabel, Tobias Heimann, Florin Ghesu, Paul Brachmann, Claus P. Heu{\ss}el, Alexander Radbruch, Gianluca Brugnara, Aditya Rastogi, Martha Foltyn-Dumitru, Heinz-Peter Schlemmer, Ignaz Reicht, Julius C. Holzschuh, Michael Bach, Bram Stieltjes, Kai Schlamp, Lena Maier-Hein, Marco Nolden, Ralf Floca, Paul F. J\"ager, Philipp Vollmuth, Fabian Isensee, Klaus H. Maier-Hein