arXiv AI By Hao Zhang, Yi Huang, Wei Liu, Yuan Gao, Zeju Li, Xu Han, Yu Shi, Ling Zhang, Ke Yan

LiFUSE: Frequency-Spatial Unified Self-Supervised Pretraining for Liver Disease Analysis on Non-contrast CT

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Hugging Face Trending Papers
3d ago

LiFUSE: Frequency-Spatial Unified Self-Supervised Pretraining for Liver Disease Analysis on Non-contrast CT

LiFUSE introduces a unified frequency‑spatial self‑supervised pretraining framework for liver disease analysis on non‑contrast CT scans. The method employs a frequency branch that uses random band‑stop masking and spectrum reconstruction, and a spatial branch that performs hybrid‑granularity masked volumetric reconstruction, with a cross‑domain consistency scheme to fuse the two branches. Experiments on three clinical tasks and a public transfer setting demonstrate that LiFUSE consistently outperforms strong baselines, indicating its potential to enhance liver disease screening using low‑contrast NCCT images.

arXiv Computer Vision
Sep 11

DINO-Med: A Unified Patch-Based Adaptation Framework for Multi-Modal Medical Image Analysis Applied to Liver Fibrosis Staging

DINO-Med introduces a patch‑based framework that adapts natural‑image foundation models, specifically DINOv3, to multi‑modal medical imaging. The method uses training‑free registration, automated localization, and mask‑filtered patch extraction to aggregate patch‑level features into subject‑level diagnostics. In liver fibrosis staging, DINOv3 outperforms handcrafted radiomics, ResNet, and SAM‑Med2D features, achieving 78.4% accuracy for mild fibrosis (S1) and 75.8% for cirrhosis (S4) on the CARE 2025 cohort.

By Boya Wang, Ruizhe Li, Chao Chen, Xin Chen
arXiv Computer Vision
Aug 26

Towards Reliable AI-Based Histological Staining: A Systematic Study of Scaling and Uncertainty in Unpaired Generative Models

The paper presents a systematic evaluation of six unsupervised image‑to‑image generative models for virtual Sirius Red staining of mouse liver tissue from routine H&E slides. It benchmarks these models across 54 scaling configurations on a newly released paired H&E‑to‑SR dataset, assessing perceptual, distributional, and task‑specific performance, and further trains the best models into deep ensembles to quantify epistemic uncertainty. The study finds that GAN‑based and diffusion‑based methods differ markedly across these metrics, indicating that reliable virtual staining requires reporting and selecting on all three axes simultaneously.

By Qasim Siddiqui, Adrian Friebel, Maiju Myllys, Zaynab Hobloss, Daniela Gonzalez, Ahmed Ghallab, Stefan Hoehme
Hugging Face Trending Papers
Sep 10

DINO-Med: A Unified Patch-Based Adaptation Framework for Multi-Modal Medical Image Analysis Applied to Liver Fibrosis Staging

The paper introduces DINO-Med, a patch‑based framework that adapts natural‑image foundation models to multi‑modal medical imaging, specifically for liver fibrosis staging. It processes raw multimodal scans through training‑free registration, automated localization, and mask‑filtered patch extraction, then aggregates patch‑level insights into subject‑level diagnostics. Using the CARE 2025 Liver Track 4 cohort, the DINOv3‑based approach achieved the highest classification accuracy (78.4% for mild fibrosis and 75.8% for cirrhosis) compared to other feature representations.