LiFUSE introduces a unified frequency‑spatial self‑supervised pretraining framework for liver disease analysis on non‑contrast CT scans. The method employs a frequency branch that uses random band‑stop masking and spectrum reconstruction, and a spatial branch that performs hybrid‑granularity masked volumetric reconstruction, with a cross‑domain consistency scheme to fuse the two branches. Experiments on three clinical tasks and a public transfer setting demonstrate that LiFUSE consistently outperforms strong baselines, indicating its potential to enhance liver disease screening using low‑contrast NCCT images.
arXiv:2610.09784v1 Announce Type: new
Abstract: Reliable liver segmentation in contrast-enhanced MRI is essential for quantitative hepatic assessment, treatment planning, and longitudinal disease mon...
By Ruoshi Xu, Mingqi Gao, Shengda Luo, Jingkun Chen
DINO-Med introduces a patch‑based framework that adapts natural‑image foundation models, specifically DINOv3, to multi‑modal medical imaging. The method uses training‑free registration, automated localization, and mask‑filtered patch extraction to aggregate patch‑level features into subject‑level diagnostics. In liver fibrosis staging, DINOv3 outperforms handcrafted radiomics, ResNet, and SAM‑Med2D features, achieving 78.4% accuracy for mild fibrosis (S1) and 75.8% for cirrhosis (S4) on the CARE 2025 cohort.
By Boya Wang, Ruizhe Li, Chao Chen, Xin Chen
The paper presents a systematic evaluation of six unsupervised image‑to‑image generative models for virtual Sirius Red staining of mouse liver tissue from routine H&E slides. It benchmarks these models across 54 scaling configurations on a newly released paired H&E‑to‑SR dataset, assessing perceptual, distributional, and task‑specific performance, and further trains the best models into deep ensembles to quantify epistemic uncertainty. The study finds that GAN‑based and diffusion‑based methods differ markedly across these metrics, indicating that reliable virtual staining requires reporting and selecting on all three axes simultaneously.
By Qasim Siddiqui, Adrian Friebel, Maiju Myllys, Zaynab Hobloss, Daniela Gonzalez, Ahmed Ghallab, Stefan Hoehme
The paper introduces DINO-Med, a patch‑based framework that adapts natural‑image foundation models to multi‑modal medical imaging, specifically for liver fibrosis staging. It processes raw multimodal scans through training‑free registration, automated localization, and mask‑filtered patch extraction, then aggregates patch‑level insights into subject‑level diagnostics. Using the CARE 2025 Liver Track 4 cohort, the DINOv3‑based approach achieved the highest classification accuracy (78.4% for mild fibrosis and 75.8% for cirrhosis) compared to other feature representations.
arXiv:2608.24364v1 Announce Type: new
Abstract: Self-supervised pretraining enables transferable representations for medical imaging, yet most CT encoders remain biased toward coarse semantic underst...
By Sebasti\'an Gonz\'alez, Karen Sanchez, Jos\'e M. Saavedra, Marcelo Pizarro, Bernard Ghanem
arXiv:2606. 16991v1 Announce Type: cross Abstract: Multiphasic contrast-enhanced CT (CECT) is widely used for abdominal lesion characterization, yet it carries inherent risks of contrast-induced nephropathy, escalates acquisition burden, and heavily contributes to radiologist workload.
By Mariam Elbakry, Aliaa Sayed Sheha, Salma Hassan Tantawy, Aya Yassin, Concetto Spampinato, Karim Lekadir, Xiaomeng Li, Marawan Elbatel
arXiv:2606. 06983v1 Announce Type: cross Abstract: Computational pathology requires visual representations that transfer across diverse clinical endpoints and remain robust to variation in magnification, staining, scanner type, slide preparation, and input resolution.
By Bokai Zhao, Yiyang Zhang, Long Bai, Tai Ma, Hanqing Chao, Minfeng Xu
arXiv:2607. 25164v1 Announce Type: cross Abstract: A CT examination captures multiple organs, but many biomedical questions concern abnormalities, prognosis, or longitudinal change in a specific organ.
By Zhixuan Ge, Anqi Li, Sadeer Al-Kindi, Hanwen Xu, Wei Qiu
arXiv:2606. 04365v1 Announce Type: cross Abstract: Radiology reports describe kidney lesions by type, size, enhancement, and attenuation, yet existing 3D methods predict only at the patient or organ level.
By Renjie Liang, Zhengkang Fan, Jinqian Pan, Chenkun Sun, Jiang Bian, Russell Terry, Jie Xu
arXiv:2608.30844v1 Announce Type: cross
Abstract: Interactive lesion segmentation in whole-body PET/CT requires a model to provide a strong initial prediction while also responding efficiently to spa...
By Xinglong Liang, Chunyao Lu, Tianyu Zhang, Jiaju Huang, Tao Tan, Yunchao Yin, Lishan Cai
arXiv:2608.00231v2 Announce Type: replace
Abstract: Volumetric CT vision-language pretraining learns 3D representations from scan-report pairs, but global and anatomy-aware objectives supervise only...
By Guoliang You, Haifan Gong, Xiaomeng Chu