The paper introduces ePID, an embedding-based approach that scales partial information decomposition (PID) to large symptom networks by compressing non‑focal symptoms into a low‑cardinality discrete embedding. Using a supervised Agglomerative Conditional Information Bottleneck (ACIB) embedding, ePID accurately recovers source‑unique, remainder‑unique, redundant, and synergistic components for each ordered source‑target pair across 83 real‑world datasets, outperforming 12 other embeddings. Applied to PHQ‑9 and the Interpersonal Reactivity Index, ePID reveals distinct patterns of redundancy and synergy that align with each instrument’s construction, demonstrating its ability to separate overlapping from interaction‑dependent information in symptom networks.
arXiv:2609.21673v1 Announce Type: new Abstract: Probabilistic Graphical Models (PGMs), especially Bayesian Networks (BNs), expose directed structure and probabilistic parameters, making them natural...
The paper introduces Omega‑N, a set of ten interpretable node‑level structural descriptors derived from localizing four factors of a composite structural index. By correcting the ill‑conditioned localization with a configuration‑null excess and a multi‑scale personalized‑PageRank neighbourhood, Omega‑N achieves competitive or superior performance in six in‑domain node‑classification tasks compared to a recursive feature engine that uses up to 252 features. In drug‑target prioritisation on protein interaction networks, Omega‑N improves AUPRC by 0.073 to 0.144 over a centrality baseline and remains robust across independent datasets and bias controls, though it offers no benefit when combined with Node2Vec. whyItMatters":"The study demonstrates that a compact, interpretable set of structural features can match or exceed more complex feature sets in practical graph‑based prediction tasks, particularly in biomedical network analysis."
arXiv:2608. 16029v1 Announce Type: new Abstract: Group Independent Component Analysis (gICA) is widely used to decompose high-dimensional functional MRI data into interpretable brain networks.
arXiv:2604. 27967v2 Announce Type: replace Abstract: Background: We introduce StructGP, a continuous-time multi-task Gaussian process that couples process convolutions with differentiable structure learning to uncover a sparse, ordered directed acyclic graph (DAG) of inter-variable dependencies while preserving principled uncertainty.
arXiv:2606. 13556v1 Announce Type: new Abstract: Personalized health AI systems face a fundamental cold-start problem: machine learning models for physiological interpretation require weeks of individual behavioral data before they can distinguish constitutional variation from environmentally driven deviation.
arXiv:2606. 18535v1 Announce Type: cross Abstract: Multi-cause observational studies contain information about unmeasured confounding through the dependence structure among causes.
arXiv:2608. 06430v1 Announce Type: new Abstract: Learning from Electronic Health Records (EHRs) has gained significant attention due to its potential to improve clinical prediction.
arXiv:2608.20380v1 Announce Type: cross Abstract: Resting-state functional magnetic resonance imaging (rs-fMRI) has enabled non-invasive mapping of functional brain interactions for computer-aided di...
arXiv:2606. 10796v1 Announce Type: cross Abstract: Automatic Depression Detection (ADD) from clinical interviews is a pivotal task in computational mental health, yet it remains challenging due to two critical obstacles: 1) difficulty in modeling complex but sparsely distributed depression clues within lengthy, multi-topic clinical interviews, leading to superficial and unreliable reasoning; 2) scarcity of labeled data due to clinical privacy, together with high cost of training and fine-tuning, limiting the deployment of supervised ADD systems.
arXiv:2407. 07357v3 Announce Type: replace Abstract: Predicting signed interactions in biological networks is crucial for understanding drug mechanisms and facilitating drug repurposing.
arXiv:2606. 07677v1 Announce Type: cross Abstract: Electronic health records (EHR) pose large-scale multi-disease modeling problems in which many outcomes are rare and strongly influenced by shared risk factors.
The paper introduces information set emulation, a method that attaches detailed causal certificates—such as source evidence, timing, and proposed causal roles—to AI‑derived features extracted from electronic health records (EHRs). These certificates provide auditable evidence for causal roles and guide whether a feature can be used for causal inference or should be routed to compatible reporting or separate analyses. The framework integrates with a joint EHR observation map and offers identification, estimation, and diagnostic tools under standard causal assumptions, illustrated through synthetic simulations and a finite‑world example.