arXiv Machine Learning

Interpretable Information-Decomposed Brain Graph Learning for fMRI-based Disease Diagnosis

arXiv Machine Learning
Oct 9

BrainATCL: Adaptive Temporal Brain Connectivity Learning for Functional Link Prediction and Age Estimation

BrainATCL is an unsupervised, nonparametric framework that learns adaptive temporal brain connectivity from resting‑state fMRI data. It dynamically adjusts the lookback window for each snapshot based on newly added edges and encodes graph sequences with a GINE‑Mamba2 backbone, incorporating brain‑structure and function‑informed edge attributes. The method is evaluated on functional link prediction and age estimation, showing superior performance and strong generalization, even across sessions.

By Yiran Huang, Amirhossein Nouranizadeh, Christine Ahrends, Mengjia Xu
arXiv Machine Learning
Sep 18

HyperAMS-Net: Adaptive Multi-Scale Spatial Hypergraph Network for Brain Disorder Classification

HyperAMS‑Net is a deep learning framework that classifies brain disorders from resting‑state fMRI or structural MRI data. It combines adaptive multi‑scale convolution, hypergraph attention, spatial‑channel attention, and adaptive feature fusion to capture complementary patterns across multiple scales and higher‑order dependencies. Evaluated on ABIDE, REST‑meta‑MDD, and ADNI datasets, it achieves state‑of‑the‑art accuracy and AUC, with ablation studies showing hypergraph attention as the most critical component.

By Proloy Kumar Mondal, Md Kamran Hussin Chowdhury, Hoi Leong Lee
arXiv Machine Learning
Jun 18

Artemis: Anatomy-Resolved inTervention for Eliminating Multimodal NeuroImage confounderS

arXiv:2606. 18287v1 Announce Type: new Abstract: Multimodal neuroimaging, integrating functional connectivity from fMRI and structural connectivity from DTI, enables non-invasive analysis of brain networks using graph neural networks.

By Siyuan Dai, Yang Du, Kun Zhao, Zhusuyi Chen, Heng Huang, Paul Thompson, Chao Shi, Haoteng Tang, Liang Zhan
arXiv Machine Learning
Sep 16

Explainable Graph-theoretical Machine Learning with Application to Alzheimer's Disease Prediction

The paper introduces Explainable Graph-theoretical Machine Learning (XGML) to build individual metabolic brain graphs from FDG-PET data and identify subgraphs predictive of multivariate Alzheimer’s disease outcomes. Using ADNI data, the best model—kernel density estimation with Hellinger distance and random forest—achieved a Pearson correlation of 0.595 across eight cognitive scores, with the highest performance on ADAS13, ADAS11, and ADASQ4. Key edges were found to be jointly but differentially predictive, indicating potential network biomarkers for cognitive decline, though external validation on OASIS3 showed weaker performance likely due to cohort differences.

By Narmina Baghirova, Duy-Thanh V\~u, Duy-Cat Can, Christelle Schneuwly Diaz, Julien Bodlet, Guillaume Blanc, Georgi Hrusanov, Bernard Ries, Oliver Y. Ch\'en