arXiv Machine Learning

Fracture Risk Prediction in Adults Over 50 Years Old Using DXA and EHR: Comparison of Traditional and Machine Learning Models in Two Large Cohorts

arXiv:2607. 28671v1 Announce Type: cross Abstract: Accurate fracture risk prediction is important for osteoporosis management, but commonly used clinical tools may not fully use information available in electronic health records (EHRs) and dual-energy X-ray absorptiometry (DXA) reports.

arXiv AI
Jun 3

DXA-Derived Skeletal Phenotypes and Hip Fracture Risk: A Backdoor-Adjusted Causal Analysis

arXiv:2606. 02625v1 Announce Type: cross Abstract: Purpose: To compare dual-energy X-ray absorptiometry (DXA)-derived hip skeletal phenotypes in relation to hip fracture risk using prespecified confounder adjustment and to assess whether phenotypes ranked by their backdoor-adjusted average treatment effects (ATEs) improve risk stratification.

By Zixin Shi, Chen Zhao, Meiling Zhou, Kevin A. Maupin, Joyce H. Keyak, Nancy E. Lane, Kuan-Jui Su, Hui Shen, Hong-Wen Deng, Kui Zhang, Weihua Zhou
arXiv Computer Vision
Aug 25

Predicting Multiple Clinical Outcomes Related to Functional Recovery and Social Isolation Among Older Adults After Lower-Limb Fracture or Hip Replacement

arXiv:2608.23531v1 Announce Type: new Abstract: Older adults recovering after lower-limb fracture or hip replacement may experience complex recovery trajectories. Most of the time, these clinical asp...

By Santosh Ray, Pratik K. Mishra, Ali Abedi, Charlene H. Chu, Amir Ahmad, Shehroz S. Khan
arXiv Machine Learning
4d ago

Does Machine Learning Outperform Traditional Fibrosis Scores in Predicting Liver Cirrhosis Risk? A Longitudinal EHR-Based Study

arXiv:2601.00175v3 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years before diagnosis using...

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv Machine Learning
Jun 2

Early Prediction of Liver Cirrhosis Up to Two Years in Advance: A Machine Learning Study Benchmarking Against the FIB-4 and APRI Scores

arXiv:2601. 00175v2 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years prior to diagnosis using routinely collected electronic health record (EHR) data and benchmark their performance against the FIB-4 and APRI clinical scores.

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv Machine Learning
Sep 18

Machine-Learning Assessment of the Predictive Value of Inflammatory Biomarkers for Cognitive Impairment in an Older Hispanic Adult Cohort

The study evaluates whether inflammatory biomarkers can predict cognitive impairment in older Hispanic adults using interpretable machine learning on a small clinical dataset. A leakage‑safe Bernoulli/Categorical Naive Bayes model was trained on 165 participants from the Panama Aging Research Initiative, with continuous predictors discretized via supervised chi‑square and income treated categorically. The biomarker I‑309 (CCL1) emerged as the sole reliable incremental predictor, boosting ROC‑AUC from 0.630 to 0.740 and achieving statistically significant performance across repeated cross‑validation and random partitions.

By Antony Garcia, Gabrielle Britton, Alcibiades Villarreal, Diana Oviedo, Giselle Rangel, Xinming Huang