arXiv:2606. 02625v1 Announce Type: cross Abstract: Purpose: To compare dual-energy X-ray absorptiometry (DXA)-derived hip skeletal phenotypes in relation to hip fracture risk using prespecified confounder adjustment and to assess whether phenotypes ranked by their backdoor-adjusted average treatment effects (ATEs) improve risk stratification.
By Zixin Shi, Chen Zhao, Meiling Zhou, Kevin A. Maupin, Joyce H. Keyak, Nancy E. Lane, Kuan-Jui Su, Hui Shen, Hong-Wen Deng, Kui Zhang, Weihua Zhou
arXiv:2608. 04025v1 Announce Type: cross Abstract: Whole-slide survival models commonly provide risk rankings without calibrated statements about individual event times.
By Mingi Hong
arXiv:2606. 10725v1 Announce Type: new Abstract: Background.
By Olga Shakhmatova, Dmitrii Kriukov, Daniil Larionov, Nikita Khromov, Iaroslav Bespalov, Alexander Zolotarev, Kirill Grishchenkov, Ekaterina Ivanova, Miron Kuznetsov, Ilya Sochenkov, Elizaveta Panchenko, Artem Shelmanov, Dmitry V. Dylov
arXiv:2606. 08305v1 Announce Type: cross Abstract: Externally controlled survival trials are increasingly used when concurrent randomized controls are infeasible, particularly in oncology and rare-disease settings with time-to-event endpoints.
By Se Yoon Lee, Yonghyun Kwon, Jae Kwang Kim
arXiv:2605. 12895v2 Announce Type: replace-cross Abstract: Clinical decision-support systems are expert systems whose recommendations clinicians act on directly, yet they are usually cleared on one aggregate accuracy number from a held-out test set.
By Rohith Reddy Bellibatlu, Manpreet Singh, Yash Jajoo, Shyamal Lakhanpal, Abhishek Israni
arXiv:2608. 08920v1 Announce Type: new Abstract: Perioperative risk prediction models are often limited by narrow surgical populations, incomplete intraoperative data, poor calibration, and limited interpretability.
By Shikhar Shukla, Cristina Barboi
arXiv:2608.23531v1 Announce Type: new
Abstract: Older adults recovering after lower-limb fracture or hip replacement may experience complex recovery trajectories. Most of the time, these clinical asp...
By Santosh Ray, Pratik K. Mishra, Ali Abedi, Charlene H. Chu, Amir Ahmad, Shehroz S. Khan
arXiv:2601.00175v3 Announce Type: replace
Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years before diagnosis using...
By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
arXiv:2601. 00175v2 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years prior to diagnosis using routinely collected electronic health record (EHR) data and benchmark their performance against the FIB-4 and APRI clinical scores.
By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed
The study evaluates whether inflammatory biomarkers can predict cognitive impairment in older Hispanic adults using interpretable machine learning on a small clinical dataset. A leakage‑safe Bernoulli/Categorical Naive Bayes model was trained on 165 participants from the Panama Aging Research Initiative, with continuous predictors discretized via supervised chi‑square and income treated categorically. The biomarker I‑309 (CCL1) emerged as the sole reliable incremental predictor, boosting ROC‑AUC from 0.630 to 0.740 and achieving statistically significant performance across repeated cross‑validation and random partitions.
By Antony Garcia, Gabrielle Britton, Alcibiades Villarreal, Diana Oviedo, Giselle Rangel, Xinming Huang
arXiv:2607. 16934v1 Announce Type: cross Abstract: Traditional randomized trials often obscure clinically meaningful heterogeneity in treatment response by focusing on average effects.
By Xiaodi Li, Munhuwan Lee, Pengyang Li, Xiaoke Liu, Jose K. James, Patricia A. Pellikka, Cui Tao, Nansu Zong
arXiv:2606. 30702v1 Announce Type: cross Abstract: Structured tabular data dominates clinical medicine, yet existing benchmarks fail to reflect real-world properties like complex survey sampling, demographic oversampling, and subgroup fairness.
By Federico Felizzi