RadOnc-Agent: An LLM-Orchestrated Framework for AI Workflows Across the Radiotherapy Care Pathway

RadOnc-Agent is an AI framework that organizes radiotherapy into four clinical phases and offers 26 callable functions via a conversational interface. A large‑language‑model controller maps clinical intent to schema‑constrained calls, maintains patient and workflow context, and routes requests to specialist services. In evaluations, the system achieved high accuracy in single‑function calls (98.79%) and cross‑stage workflow completions (96.50% scripted, 96.67% real‑patient), demonstrating technical feasibility of LLM‑orchestrated coordination across heterogeneous radiotherapy capabilities.

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• llms
• agents