arXiv AI By Qingqing Wang, Liqiang Xiao, Chang Chang

An Evidence-Driven Multi-Agent Compound AI System for Head and Neck Proton Radiotherapy Planning

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The paper presents an evidence-driven, multi-agent AI system for head and neck proton radiotherapy planning. It combines a DRL-based planning agent that generates multiple treatment plans with an LLM-based conversational agent that refines the chosen plan through natural language interactions. The system, trained on 21 patients, improves instruction-following and domain-specific reasoning, yielding more clinically appropriate trade-offs in patient-specific plan refinement.

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arXiv AI
Oct 7

RadOnc-Agent: An LLM-Orchestrated Framework for AI Workflows Across the Radiotherapy Care Pathway

RadOnc-Agent is an AI framework that organizes radiotherapy into four clinical phases and offers 26 callable functions via a conversational interface. A large‑language‑model controller maps clinical intent to schema‑constrained calls, maintains patient and workflow context, and routes requests to specialist services. In evaluations, the system achieved high accuracy in single‑function calls (98.79%) and cross‑stage workflow completions (96.50% scripted, 96.67% real‑patient), demonstrating technical feasibility of LLM‑orchestrated coordination across heterogeneous radiotherapy capabilities.

By Caiwen Jiang, Shuoyang Wei, Songlin Zhao, Junyu Li, Jingyuan Chen, Wei Liu
arXiv AI
Jun 30

An AI agent for treatment reasoning over a biomedical tool universe

arXiv:2606. 28692v1 Announce Type: new Abstract: Treatment reasoning underpins every therapeutic decision, integrating disease context, comorbidities, medications, contraindications, and evolving biomedical knowledge to select an appropriate therapy.

By Shanghua Gao, Ayush Noori, Richard Zhu, Curtis Ginder, Zhenglun Kong, Xiaorui Su, Justin Kauffman, Benjamin S. Glicksberg, Joshua Lampert, Ankit Sakhuja, Ashwin Sawant, ATHENA-R1 Evaluation Consortium, David A. Clifton, Noa Dagan, Ran Balicer, Marinka Zitnik
arXiv AI
Jun 16

Toward Vibe Medicine: A Self-Evolving Multi-Agent Framework for Clinical Decision Support

arXiv:2606. 15504v1 Announce Type: new Abstract: In recent years, the advances of large language models and autonomous agents have revolutionized the healthcare field, facilitating diagnosis and improving treatment results.

By Qianxue Zhang, Yiming Ren, Shihuan Qin, Xiao Zhang, Liao Zhang, Jinyang Huang, Zhengliang Liu, Chenbin Liu, Hongying Feng, Jingyuan Chen, Yuzhen Ding, Weihang You, Hanqi Jiang, Yi Pan, Yifan Zhou, Junhao Chen, Lifeng Chen, Wei Liu, Tianming Liu, Zengren Zhao, Lian Zhang
arXiv AI
Sep 15

ClinAgent: A ReAct-Based Agent for Conversational Access to Clinical Trial Information

ClinAgent is a conversational system that uses a ReAct-based LLM agent to retrieve and synthesize clinical trial information from multiple sources such as ClinicalTrials.gov, PubMed, and a local dataset. The agent iteratively reasons over user queries, selects appropriate tools, and refines its actions to provide grounded, up-to-date responses in natural language across multi-turn interactions. Evaluation across three phases shows that DeepSeek (thinking mode) excels in planning quality while Gemini 3.0 Flash delivers the highest overall performance and expert ratings, demonstrating the promise of agentic AI for improving clinical trial data access.

By Antonino Vaccarella, Riccardo Cantini, Domenico Talia, Paolo Trunfio, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini