FlowMoDL is an unrolled neural network designed for highly accelerated 4D flow MRI reconstruction, optimizing both anatomical magnitude and phase-derived velocity accuracy. It alternates a learned (3+1)D spatiotemporal denoiser with conjugate‑gradient data‑consistency updates, using a dual‑pathway conditioning scheme to handle acceleration factors from 10× to 50×. Trained with a deep‑supervision composite loss that penalizes velocity magnitude and angular errors, FlowMoDL outperforms classical and deep‑learning baselines on the multi‑center CMRx4DFlow dataset, achieving superior gradient‑step efficiency and robust convergence across all acceleration factors.
By Tristan Gottwald, Michelle Bruch, Mubashir-Ul Hassan, Fatma Alickovic, Milan Kloiber, Daniel Tenbrinck, Torsten Panholzer, Melanie Schaller, Jana Hutter
arXiv:2606. 06313v1 Announce Type: cross Abstract: Wall shear stress (WSS) governs near-wall transport dynamics and is a key hemodynamic indicator in cardiovascular flows, yet remains difficult to infer accurately due to the need for precise computation of near-wall velocity gradients.
By Mahmoud Elhadidy, Siva Viknesh, Roshan M. D'Souza, Amirhossein Arzani
The study presents a multimodal BrainAGE framework that fuses structural T1-weighted MRI with DeepCBV maps—vascular information synthesized from non‑contrast MRI—to estimate brain age more accurately. Using two separate 3D convolutional neural networks, the combined model achieved a mean absolute error of 3.95 years on cognitively normal controls, outperforming single‑modality models. Saliency analyses showed MRI highlighted white matter and cortical atrophy, while DeepCBV emphasized vascular‑rich regions, and the integrated approach revealed stronger differentiation between stable and progressive MCI, indicating sensitivity to early vascular changes.
By Jordan Jomsky, Zongyu Li, Kay C. Igwe, Yiren Zhang, Max Lashley, Tal Nuriel, Andrew Laine, Scott A. Small, Jia Guo, for the Frontotemporal Lobar Degeneration Neuroimaging Initiative, for the Alzheimer's Disease Neuroimaging Initiative
X‑LMC is a spatiotemporal deep‑learning framework that automatically scores leptomeningeal collateral (LMC) status from time‑resolved biplane digital subtraction angiography (DSA). It uses a DINOv2 backbone to encode spatial frames, a token‑level cross‑view attention module to fuse orthogonal projections, and a recurrent network to model contrast bolus dynamics. On a multicenter dataset of 134 M1‑segment occlusion patients, X‑LMC achieved a Quadratic Weighted Kappa of 0.398 and a macro‑F1 of 0.711, outperforming static and other spatiotemporal baselines and matching clinical inter‑rater agreement.
arXiv:2608.30975v1 Announce Type: cross
Abstract: Cardiac magnetic resonance imaging (CMR) produces rich sequential data such as temporal cine videos and spatial LGE/mapping stacks, yet most deep lea...
By Athira J. Jacob, Puneet Sharma, Dorin Comaniciu, Daniel Rueckert
The study presents a fully automated 4D U‑Net that segments the ascending aorta, arch, and proximal descending aorta in 4D flow MRI using a hybrid 4D convolutional kernel and sparse 4D labels derived from 2D expert contours and centerlines. Trained on 268 scans from eight centers, the model achieved high Dice scores (0.927 internal, 0.911 external) and excellent agreement with expert measurements of peak velocity, net flow, wall shear stress, and diameters (ICC ≥0.954 internal, ≥0.980 external). Compared to frame‑wise 3D networks and semi‑automatic methods, the 4D U‑Net outperformed in diastole and generalised well to independent post‑contrast data.
By Hinrich Rahlfs, Julio Garcia, Chiara Manini, Markus H\"ullebrand, Sebastian Schmitter, Sarah Nordmeyer, Titus K\"uhne, Heiko Stern, Christian Meierhofer, Andreas Harloff, Sebastian Kelle, Alexander Lenz, Peter Bannas, Jeanette Schulz-Menger, Ralf F Trauzeddel, Anja Hennemuth