arXiv:2609.37642v1 Announce Type: new
Abstract: Self-supervised pretraining reshaped prediction in language and vision, and brain foundation models (BFMs) inherited its promise. Representations learn...
By Giovanni Marraffini (UNITO), Victoria Shevchenko (UNITO), Carlo Alberto Barbano (UNITO), Demian Wassermann (MIND)
The study investigates how data volume, model size, and training duration affect the performance of fMRI foundation models. Using over 200 datasets and 10,000 GPU‑hours, the authors find that larger models benefit more from additional data, and that at a fixed compute budget, increasing data yields greater gains than enlarging the model. By selecting optimal combinations of data, size, and duration, they produce models that outperform existing fMRI foundation models on out‑of‑distribution tasks while requiring less pretraining compute.
By Wenhao Ye, Xuanye Pan, Junfeng Xia, Junxiang Zhang, Mo Wang, Quanying Liu
arXiv:2609.10518v1 Announce Type: new
Abstract: fMRI foundation models increasingly aggregate heterogeneous data across brain states, cohorts, and acquisition settings, yet pretraining domains are co...
By Junfeng Xia, Wenhao Ye, Junxiang Zhang, Jiayu Zuo, Mo Wang, Quanying Liu
arXiv:2609.34167v2 Announce Type: replace
Abstract: Foundation models pre-trained on large-scale fMRI datasets have shown strong downstream performance, but at substantial data and computation cost....
By Juhyeon Park, Yeonwoo Kim, Peter Yongho Kim, Yansen Wang, Mingqing Xiao, Dongqi Han, Dongsheng Li, Taesup Moon
arXiv:2607. 16292v1 Announce Type: cross Abstract: Brain-encoding foundation models predict fMRI responses to video, audio, and text well enough to win the Algonauts 2025 challenge.
By Carson Rodrigues
Rhamba is a region‑aware pretraining framework for resting‑state fMRI that combines anatomically guided masking with hybrid Attention‑Mamba architectures. The study pretrained models on the ABIDE dataset using three masking strategies (Any, Majority, Pure) and evaluated four architectural variants, finding that the Mamba‑Attention (MA) hybrid achieved the best average AUROC on downstream schizophrenia and ADHD classification tasks. Explainable AI via Integrated Gradients highlighted that performance depends on the interaction between masking strategy and architecture rather than a single dominant configuration.
By Pankaj Pandey, Ruthwik Reddy Doodipala, Pratheek Eranki, Carolina Torres-Rojas, Manob Jyoti Saikia, Ranganatha Sitaram
arXiv:2607. 06629v1 Announce Type: new Abstract: Brain age -- the age inferred from a physiological recording -- is an emerging biomarker whose deviation from chronological age tracks neurological and psychiatric burden, and EEG is an attractive substrate for it because it is cheap, portable, and temporally rich.
By Roy Segal, Yoni Svechinsky, Tomer Fekete
M$^2$PFN is an end‑to‑end multimodal framework that extends the TabPFN in‑context learning engine to Alzheimer’s disease diagnosis by aligning 3D‑MRI and tabular features in a shared subspace. It performs differentiable inference through TabPFN’s transformer, back‑propagates gradients into the encoders, and incorporates a frozen tabular‑only prediction via a gated shortcut. On the ADNI cohort it achieves 65.55 % macro‑F1 and 82.21 % macro‑AUC, surpassing unimodal and multimodal baselines, and it generalizes to external cohorts without retraining.
By Lujia Zhong, Shuo Huang, Jianwei Zhang, Xinyu Nie, Yonggang Shi
BrainFedFM is a structural brain MRI foundation model that was federatively pretrained on 164,707 3‑D scans from 42 sites using a dual‑priority approach that emphasizes informative anatomical regions locally and prioritizes site contributions globally. The model outperformed seven baseline models—including four centralized foundation models—across 20 downstream tasks (classification, regression, segmentation), achieving a mean rank of 1.68 and a 50% performance gain, especially in classification and regression and among underrepresented populations. These results demonstrate the model’s generalizability and show that federated pretraining can effectively develop neuroimaging foundation models without pooling raw images.
By Zhen Yu, Yang Liu, Xiahai Zhuang, Qingchao Chen
arXiv:2609.40127v1 Announce Type: cross
Abstract: Modern transformers pair impressive capabilities with substantial memory and compute demands. Low-rank weight factorization reduces both while keepin...
By Massimo Bini, Anders Christensen, Stephan Alaniz, Judah Goldfeder, Ole Winther, Yann LeCun, Ravid Shwartz-Ziv, Zeynep Akata
arXiv:2607. 16292v4 Announce Type: replace-cross Abstract: Brain-encoding foundation models predict fMRI responses to video, audio and text well enough to win the Algonauts 2025 challenge.
By Carson Rodrigues
arXiv:2609.01170v1 Announce Type: new
Abstract: Large language models exhibit a modular internal organization that mirrors well-studied functional networks of the human brain, but how this organizati...
By Guangqi Li, Yongxin Li