BrainFedFM is a structural brain MRI foundation model that was federatively pretrained on 164,707 3‑D scans from 42 sites using a dual‑priority approach that emphasizes informative anatomical regions locally and prioritizes site contributions globally. The model outperformed seven baseline models—including four centralized foundation models—across 20 downstream tasks (classification, regression, segmentation), achieving a mean rank of 1.68 and a 50% performance gain, especially in classification and regression and among underrepresented populations. These results demonstrate the model’s generalizability and show that federated pretraining can effectively develop neuroimaging foundation models without pooling raw images.
By Zhen Yu, Yang Liu, Xiahai Zhuang, Qingchao Chen
arXiv:2609.34167v2 Announce Type: replace
Abstract: Foundation models pre-trained on large-scale fMRI datasets have shown strong downstream performance, but at substantial data and computation cost....
By Juhyeon Park, Yeonwoo Kim, Peter Yongho Kim, Yansen Wang, Mingqing Xiao, Dongqi Han, Dongsheng Li, Taesup Moon
arXiv:2609.37642v1 Announce Type: new
Abstract: Self-supervised pretraining reshaped prediction in language and vision, and brain foundation models (BFMs) inherited its promise. Representations learn...
By Giovanni Marraffini (UNITO), Victoria Shevchenko (UNITO), Carlo Alberto Barbano (UNITO), Demian Wassermann (MIND)
arXiv:2606. 06345v1 Announce Type: cross Abstract: Brain decoding is limited by the availability of labeled neural data, and remains challenging in low-data regimes.
By Yohann Benchetrit, Marl\`ene Careil, Simon Dahan, Hubert Banville, St\'ephane d'Ascoli, Jean-R\'emi King
arXiv:2606. 04010v1 Announce Type: cross Abstract: Brain foundation models (BFMs) are self-supervised Transformers pretrained on fMRI data.
By Giovanni Marraffini, Gabriel Mahuas, Trinidad Borrell, Victoria Shevchenko, Demian Wassermann
arXiv:2604. 18827v2 Announce Type: replace-cross Abstract: Scaling data and artificial neural networks has transformed AI, driving breakthroughs in language and vision.
By Konstantin F. Willeke, Polina Turishcheva, Alex Gilbert, Goirik Chakrabarty, Hasan A. Bedel, Paul G. Fahey, Yongrong Qiu, Marissa A. Weis, Michaela Vystr\v{c}ilov\'a, Taliah Muhammad, Lydia Ntanavara, Rachel E. Froebe, Kayla Ponder, Zheng Huan Tan, Emin Orhan, Erick Cobos, Sophia Sanborn, Katrin Franke, Fabian H. Sinz, Alexander S. Ecker, Andreas S. Tolias