The article introduces MedGPT Clinical Explorer (MCE), a conditional‑strategy framework designed to aid complex lung cancer decision‑making by explicitly mapping patient conditions to pathway eligibility, deferral, and redirection. In a study with 250 physicians across 98 institutions, MCE‑assisted strategies achieved higher Admissible Pathway Attainment Scores (APAS) than unaided or retrieval‑reference approaches, indicating more comprehensive inclusion of clinically relevant content and coherent links among pathways, conditions, and actions. The authors suggest that MCE’s shared decision object could improve transparency of omissions and contingencies, warranting prospective evaluation of its impact on workflow and patient outcomes.
By Daoyun Wang, Zhicheng Huang, Huaiyuan Sun, Jiaqi Xu, Xiaowei Xu, Zhibo Zheng, Zhongxing Bing, Yuxiao Lin, Yicheng Liang, Chao Gao, Bowen Xue, Kai Zhang, Song Xu, Wanpu Yan, Hui Xia, Lin Li, Xiang Yan, Mu Hu, Qianli Ma, Zhiqiang Xue, Xiaofang Liu, Zhihai Han, Nan Zhang, Chuanhao Tang, Tongmei Zhang, Lan Song, Zhaohui Zhu, Xuan Zeng, Shafei Wu, Hui Guan, Lei Deng, Huaxia Yang, Zeliang Lian, Wubin Sun, Yongxin Wang, Xiaohui Shen, Binlin Wang, Tiantian Gu, Yu Cui, Li Zhang, Shirui Wang, Naixin Liang
arXiv:2608. 15004v1 Announce Type: cross Abstract: Lung cancer remains one of the leading causes of cancer-related mortality worldwide, and Computed Tomography (CT) is a primary imaging tool for screening and followup assessment.
By Pramit Dutta, Jenita Manokaran, Richa Mittal, Ryan Appleby, Eranga Ukwatta
arXiv:2609.22281v1 Announce Type: new
Abstract: Foundation models have recently demonstrated strong capabilities across a wide range of medical imaging tasks. However, their performance in structured...
By Benjamin Renoust, Pierre Baudot, Tiffany Foriel, Yousra Haddou, Charles Voyton, Pierre-Henri Siot, Ezequiel Geremia, Danny Francis, Jean-Christophe Brisset, Val\'erie Bourd\`es, Sylvain Bodard, Benoit Huet
The paper introduces AI Consilium, a benchmark for evaluating large language models (LLMs) on providing clinically grounded, coherent, actionable, and safe second opinions in multidisciplinary settings. Using 300 NEJM–MedQA cases, the study compares eight single-model pipelines that generate role-specific opinions and interactive-consilium reports under free-form and structured conditions. Results show that structured final reports generally score higher, especially in management, and that GPT‑5.6‑Sol outperforms other models across all evaluated components, demonstrating the benchmark’s ability to differentiate model capabilities and the impact of response structure.
By Alexey A. Bokov, Ivan I. Panin, Nikolay B. Nechaev, Mikhail Yu. Valkov, Valeria Yu. Chernina, Natalia Gombolevskaya, Ayyaz Hussain, Vladimir M. Agafonov, Victor A. Gombolevskiy, Aleksandr V. Nesterov, Iaroslav R. Bespalov, Ivan V. Oseledets, Dmitry V. Dylov
The study evaluates the robustness of medical vision‑language models for tuberculosis screening on chest X‑rays by testing them across multiple datasets, prompts, and evaluation settings. Three specialized models (BioMedCLIP, CheXficient, MedSigLIP) and a general OpenCLIP model were audited on 12,200 images, producing 244,000 model–image–prompt scores. Results show that no model consistently outperforms others across all cohorts and reliability criteria, with prompt changes and control group composition significantly affecting AUROC, and that high training‑set performance does not reliably transfer to external cohorts.
By Mushir Akhtar, M. Tanveer, Mohd. Arshad
arXiv:2607. 02175v1 Announce Type: new Abstract: Multiple-choice medical benchmarks are increasingly saturated, and recent rubric-based evaluations such as HealthBench have shown that open-ended clinical performance is far from solved - its "Hard" subset top score remains 32%.
By Samiha A. Ismail, Fan X. Chen, Ali Merali
arXiv:2609.01470v1 Announce Type: new
Abstract: As AI systems are increasingly used to draft radiology reports, reliably evaluating their clinical quality remains a critical challenge. Large language...
By Charles Corbi\`ere, L\'eo Machado, Aubin Charley, Baptiste Callard, Pierre Manceron, Corentin Dancette
arXiv:2609.37750v1 Announce Type: cross
Abstract: Pulmonary embolism (PE) is a leading cause of cardiovascular mortality, yet the real-world performance of FDA-cleared AI detection models remains inc...
By Aawez Mansuri, Mohammadreza Chavoshi, Theodorus Dapamede, Wasif Bala, Beatrice Brown-Mulry, Rohan Isaac, Bardia Khosravi, Hanzhou Li, Frank Li, John T. Moon, Chad Robichaux, Dan I. G. Cohen-Addad, Ninad V. Salastekar, Janice Newsome, Judy W. Gichoya, Hari Trivedi
The study investigates how refined annotations versus model training changes affect pulmonary embolism segmentation performance. By re‑annotating 149 CT pulmonary angiography cases and evaluating two pretrained nnU-Net models, the authors find that improving annotation quality increases the Dice similarity coefficient (DSC) by 0.143–0.188, far exceeding the 0.028 DSC change from altering training datasets. A new human‑referenced benchmark model (nnPE) was trained and publicly released, though it performed below all annotators in paired comparisons.
By Qihang Sun, Zhongxiao Liu, Bailiang Jian, Shenman Qiu, Jingyuan Wang, Lei Zhang, Lixiang Xie, Jiazhen Pan, Christian Wachinger
The paper introduces the Cross‑Modal Triage Network (CMTN), a multimodal deep‑learning model that fuses a Swin Transformer V2 visual encoder with a PubMedBERT text encoder to perform severity‑based triage, pathology detection, and generate visual explanations for chest radiographs. Trained on 34,639 image‑text pairs from MIMIC‑CXR‑JPG, the CMTN achieves high ordinal agreement with reference labels (QWK = 0.9341) and excellent pathology detection (macro‑AUROC = 0.9970) while operating with 34 ms latency. However, a blinded clinical audit revealed low agreement with expert radiologists (QWK = 0.1399) and only modest spatial‑semantic concordance in heatmaps, underscoring the gap between algorithmic performance and clinical judgment.
By Zinah Ghulam, Richa Mittal, Eranga Ukwatta
arXiv:2607. 05880v1 Announce Type: cross Abstract: Imaging demand is growing faster than the radiology workforce can expand, and reporting backlogs cannot be resolved through training and recruitment alone.
By Suneeta Mall, Vladimir Nekrasov, Ashnil Kumar, Sajith Karunasena, Aiden Nibali, Alix Bird, Mateo Diaz Shine, Jarrel Seah
arXiv:2609.00909v1 Announce Type: new
Abstract: Reliable evaluation of automated coronary computed tomography angiography (CCTA) report generation requires standardized multicentre benchmarks and cli...
By Zhiyu Ye, Yue Sun, Limiao Zou, Cheng Xu, Keting Xu, Tong Hu, Yue Yu, Hairong Zheng, Yining Wang, Tong Zhang