arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.
By Sandhanakrishnan Ravichandran, Shivesh Kumar, Rogerio Corga Da Silva, Miguel Romano, Reinhard Berkels, Michiel van der Heijden, Olivier Fail, Valentine Emmanuel Gnanapragasam
arXiv:2606. 28960v1 Announce Type: new Abstract: Physicians now pose millions of clinical questions to AI tools each week, yet these tools are evaluated largely on hypothetical or exam-style questions, not those actually asked in practice.
By Jean Feng, Vishal Patel, Patrick Heagerty, Yifan Mai, Venkatesh Sivaraman, Patrick Vossler, Jialin Ouyang, Anupam B. Jena
arXiv:2608. 12138v1 Announce Type: cross Abstract: General-purpose large language models (LLMs) have recently been reported to match or exceed specialized clinical AI tools on medical benchmarks, but such comparisons draw on a narrow set of systems and on benchmarks developed largely in high-income settings.
By Praveen Reddy, Charuta Mandke, Suvrankar Datta, Sarah Khan, Siddharth Reddy Anthireddy, Shitij Arora, Vishal Singh
arXiv:2604. 14892v3 Announce Type: replace-cross Abstract: Evaluating medical AI systems using expert clinician panels is costly and slow, motivating the use of large language models (LLMs) as alternative adjudicators.
By Amy Rouillard, Sitwala Mundia, Linda Camara, Ziyaad Dangor, Michael Cameron Gramanie, Ismail Kalla, Shabir A. Madhi, Kajal Morar, Marlvin T. Ncube, Haroon Saloojee, Bruce A. Bassett
arXiv:2606. 03198v1 Announce Type: cross Abstract: Clinical AI evaluation increasingly delegates scoring to large language models (LLMs) acting as AI raters, yet their scoring behavior across evaluation conditions has not been quantitatively characterized.
By Sangwon Baek, Kyu Yeon Hur, Kyunga Kim
arXiv:2409. 07314v3 Announce Type: replace-cross Abstract: While Large Language Models (LLMs) achieve superhuman performance on standardized medical licensing exams, these static benchmarks have become saturated and increasingly disconnected from the functional requirements of clinical workflows.
By Praveenkumar Kanithi, Cl\'ement Christophe, Marco AF Pimentel, Tathagata Raha, Prateek Munjal, Nada Saadi, Hamza A Javed, Svetlana Maslenkova, Nasir Hayat, Ronnie Rajan, Shadab Khan
arXiv:2608. 14212v1 Announce Type: new Abstract: As large language models enter professional domains, they must satisfy domain constraints, include critical evidence, and provide complete reasoning rather than merely produce fluent responses.
By Xukai Wang, Liangqi Li, Zhiyue Xu, Jingang Zhou, Xiaoyu Shi, Jiansheng Cai, Bo Zhang, Zhe Li, Xu-Yao Zhang
arXiv:2606. 16890v1 Announce Type: cross Abstract: Aggregate accuracy benchmarks conceal a systematic structure in how large language models fail at electronic health record (EHR) question answering: questions requiring more inferential steps produce disproportionately more errors.
By Sanjay Basu
arXiv:2606. 05436v1 Announce Type: new Abstract: Summarizing the latest medical literature to guide clinical decision-making is essential for evidence-based medicine and high-quality patient care.
By Alejandro Lozano, Keiko Ihara, Ping-Hao Yang, Carrie E. Robertson, Jennifer Stern, Allan Purdy, Hsiangkuo Yuan, Pengfei Zhang, Yulia Orlova, Olga Fermo, Jennifer Hranilovich, Fred Cohen, Todd J. Schwedt, Jenelle A. Jindal, Serena Yeung-Levy, Chia-Chun Chiang
arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.
By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang
arXiv:2606. 09030v1 Announce Type: cross Abstract: Clinical early warning systems built on electronic health records, in which clinical observations are recorded as irregularly sampled medical time series (ISMTS), must deliver both calibrated risk scores for patient triage and interpretable rationales that clinicians can verify.
By Hyeongwon Jang, Gyouk Chu, Changhun Kim, Joonhyung Park, Hangyul Yoon, Eunho Yang
arXiv:2606. 18203v1 Announce Type: cross Abstract: The LLM-empowered personal health agents with user health (sensor) metrics have offered a promising pathway to alleviate global disparities in healthcare access.
By Weizhi Zhang, Zechen Li, Hamid Palangi, Ben Graef, A. Ali Heydari, Simon A. Lee, Salman Rahman, Ray Luo, Zeinab Esmaeilpour, Erik Schenck, Chloe Zhang, Yamin Li, Menglian Zhou, Philip S. Yu, Daniel McDuff, Lindsey Sunden, Mark Malhotra, Shwetak Patel, Ahmed A. Metwally