arXiv:2610.33054v1 Announce Type: new
Abstract: Simulating an individual's disease course requires connecting patient history to future events, clinical timing and disease morphology. Longitudinal pr...
By Youcheng Li (Peking University, Isoplex Lab), Fa Tian (Isoplex Lab), Binbin Su (Peking Union Medical College, Isoplex Lab)
The paper presents M2-OPMDNet, a multimodal deep learning framework that combines white‑light and autofluorescence intraoral images with structured clinical data to detect oral potentially malignant disorders (OPMDs). Using a prospectively collected real‑world dataset, the model achieved an AUC of 0.952, outperforming unimodal approaches and improving detection of visually subtle lesions. Explainability was provided through SHAP analysis, showing that clinical variables significantly contributed to risk estimation alongside imaging features.
By Ruilin You, Yihan Wang, Jiabin Chen, Cherie Wink, Petra Wilder-Smith, Rongguang Liang, Bofan Song
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
By Jingyu Hu, Giuseppe Tripodi, Reed Naidoo, Sarah F. McGough, Tapabrata Chakraborti
arXiv:2608. 04025v1 Announce Type: cross Abstract: Whole-slide survival models commonly provide risk rankings without calibrated statements about individual event times.
By Mingi Hong
Automated radiology report generation is advancing rapidly in response to the shortage of radiologists, yet unlike a perception model, existing generation models offer no control over the sensitivity-specificity trade-off of their diagnostic content. Such control is essential because clinical scenarios diverge: emergency triage prioritizes sensitivity to reduce missed findings, whereas confirmatory interpretation emphasizes specificity to limit unnecessary interventions.
arXiv:2608. 10505v1 Announce Type: new Abstract: Automated radiology report generation is advancing rapidly in response to the shortage of radiologists, yet unlike a perception model, existing generation models offer no control over the sensitivity-specificity trade-off of their diagnostic content.
By Ying Jin, Noel C. F. Codella, John Corring, Mu Wei, Dinei Florencio, Eric Horvitz
The article introduces MedGPT Clinical Explorer (MCE), a conditional‑strategy framework designed to aid complex lung cancer decision‑making by explicitly mapping patient conditions to pathway eligibility, deferral, and redirection. In a study with 250 physicians across 98 institutions, MCE‑assisted strategies achieved higher Admissible Pathway Attainment Scores (APAS) than unaided or retrieval‑reference approaches, indicating more comprehensive inclusion of clinically relevant content and coherent links among pathways, conditions, and actions. The authors suggest that MCE’s shared decision object could improve transparency of omissions and contingencies, warranting prospective evaluation of its impact on workflow and patient outcomes.
By Daoyun Wang, Zhicheng Huang, Huaiyuan Sun, Jiaqi Xu, Xiaowei Xu, Zhibo Zheng, Zhongxing Bing, Yuxiao Lin, Yicheng Liang, Chao Gao, Bowen Xue, Kai Zhang, Song Xu, Wanpu Yan, Hui Xia, Lin Li, Xiang Yan, Mu Hu, Qianli Ma, Zhiqiang Xue, Xiaofang Liu, Zhihai Han, Nan Zhang, Chuanhao Tang, Tongmei Zhang, Lan Song, Zhaohui Zhu, Xuan Zeng, Shafei Wu, Hui Guan, Lei Deng, Huaxia Yang, Zeliang Lian, Wubin Sun, Yongxin Wang, Xiaohui Shen, Binlin Wang, Tiantian Gu, Yu Cui, Li Zhang, Shirui Wang, Naixin Liang
arXiv:2603. 28387v2 Announce Type: replace Abstract: Trustworthy clinical AI requires that performance gains reflect genuine evidence integration rather than surface-level artifacts.
By Doan Nam Long Vu, Simone Balloccu
arXiv:2608.24688v1 Announce Type: new
Abstract: Precision oncology necessitates a longitudinal model of patient state that captures cancer evolution and treatment over time, integrating multimodal ob...
By Eugene Vorontsov, Yi Kan Wang, Alican Bozkurt, Adam Casson, Ludmila Tydlitatova, Michal Zelechowski, Ezra E. W. Cohen, Jyoti D. Patel, Max Banaszak, Caitlin McWilliams, Shane Colley, Kate Sasser, Ryan Fukushima, Eric Lefkofsky, Razik Yousfi, Siqi Liu
arXiv:2606. 19966v1 Announce Type: cross Abstract: Whole-slide images (WSIs) are widely used for computational cancer prognosis.
By Yucheng Xing, Ling Huang, Pei Liu, Jingying Ma, Jiaqing Xu, Kai He, Mengling Feng
arXiv:2610.17603v1 Announce Type: cross
Abstract: Background: Five-year survival prediction from hematoxylin-and-eosin whole-slide images could support risk stratification, but the task is weakly sup...
By Hikmat Khan, Metin N. Gurcan, Anil Parwani, Wendy L. Frankel, Wei Chen, Muhammad Khalid Khan Niazi
arXiv:2605. 25050v2 Announce Type: replace-cross Abstract: Integrating multimodal datasets in clinical oncology is frequently hindered by high dimensionality and blockwise missingness, where entire data sources are unavailable for specific patient subsets.
By Mohamed Boussena, Florence Monville, Jacques Fieschi-Meric, Frederic Vely, Pierre Milpied, Julien Mazieres, Maurice Perol, Eric Vivier, Laurent Greillier, Fabrice Barlesi, Sebastien Benzekry