arXiv:2607. 16325v1 Announce Type: cross Abstract: Foundation models provide powerful representations for brain MRI analysis, but their predictions remain difficult to interpret in anatomically meaningful terms.
By Wei Zhang
arXiv:2608. 12689v1 Announce Type: cross Abstract: Multi-parametric magnetic resonance imaging (mpMRI) is a cornerstone for brain tumor diagnosis and treatment, yet current AI models face critical limitations: their lack of natural language interaction and interpretability impedes spatial information integration and cross-modal reasoning required clinically.
By Zhi Qiao, Xintong Wu, Yichu He, Feng Shi
arXiv:2607. 16303v1 Announce Type: cross Abstract: Medical Vision-Language Models (Med-VLMs) require reliable reasoning from fine-grained visual evidence, yet existing models can produce plausible clinical answers by relying on language priors or medical templates rather than truly attending to diagnosis-critical regions.
By Yunhang Qian, Jiaquan Yu, Jiawei Liu, Meng Wang, Hongwei Bran Li, Xiaobin Hu
Medical vision-language models typically generate diagnoses through single-pass inference without indicating which image regions support their conclusions. This lack of spatial grounding limits clinical utility: outputs cannot be audited, and models may hallucinate findings on normal scans.
arXiv:2608. 08926v1 Announce Type: new Abstract: Neuroimaging and genetic testing are two important clinical references for nervous system diseases, offering complementary diagnostic information.
By Tianli Tao, Ziyang Wang, Emma Robinson, Rachel Sparks, Le Zhang
arXiv:2606. 00123v1 Announce Type: cross Abstract: Multimodal Large Language Models (MLLMs) have shown strong performance on public medical benchmarks, yet existing evaluations often remain weak proxies for clinical use, relying on isolated inputs and simplified recognition-style tasks.
By Zixian Su, Hongkai Zhang, Fan Gao, Encheng Su, Taiping Qu, Jingwei Guo, Nan Zhang, Hui Wang, Zhen Zhou, Kairui Bo, Yan Chen, Yue Ren, Shuai Li, Lei Xu, Henggui Zhang
arXiv:2604. 26283v3 Announce Type: replace-cross Abstract: High-precision medical diagnosis relies not only on static imaging features but also on the implicit diagnostic memory experts instantly invoke during image interpretation.
By Chunzheng Zhu, Jiaqi Zeng, Junyu Jiang, Jianxin Lin, Yijun Wang
arXiv:2607. 25933v1 Announce Type: cross Abstract: Clinical diagnostic evaluation should not only assess whether models can provide correct diagnoses, but also reflect the realities of clinical practice, including progressive disclosure of multimodal information, dynamic updating of diagnostic hypotheses, and continuous refinement of clinical reasoning.
By Rui Yang, Weihao Xuan, Yi Lin, Zhuhan Bao, Jonathan Chong Kai Liew, Matthew Yu Heng Wong, Nicol\'as Lescano, Nikita R. Paripati, Emily Ling-Lin Pai, Jiarui Liu, Heli Qi, Heng-Jui Chang, Benny Kai Guo Loo, Huitao Li, Kunyu Yu, Yufan Wang, Chuan Hong, Shijian Lu, Douglas Teodoro, Naoto Yokoya, Ross Koppel, Mona Diab, Hua Xu, David W. Bates, Nan Liu, Yifan Peng
arXiv:2608. 00076v2 Announce Type: replace-cross Abstract: Multimodal large language models (MLLMs) increasingly support high-stakes decision making by combining complementary information from images and text.
By Vahidin Hasic, Chao Wang, Luis C. Garcia-Peraza-Herrera, David Watson, Senka Krivic
arXiv:2411. 15490v2 Announce Type: replace-cross Abstract: Acute ischemic stroke (AIS) requires time-critical decision-making, where inaccurate interpretation of neuroimaging findings can lead to irreversible disability.
By Junhyeok Lee, Yujin Oh, Dahyoun Lee, Hyon Keun Joh, Chul-Ho Sohn, Sung Hyun Baik, Cheol Kyu Jung, Jung Hyun Park, Kyu Sung Choi, Byung-Hoon Kim, Jong Chul Ye
arXiv:2607. 27304v1 Announce Type: new Abstract: Medical vision-language models (VLMs) generate chain-of-thought (CoT) reasoning before answering clinical questions, but whether this reasoning causally influences predictions remains unclear.
By Supratik Bhowal, Subhrajyoti Basu, Aritra Gir Mahanta, Anik Pal Chowdhury
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
By Jingyu Hu, Giuseppe Tripodi, Reed Naidoo, Sarah F. McGough, Tapabrata Chakraborti