arXiv Machine Learning

A Filtered Mixture-of-Generators for Fully Synthetic Survival Training

arXiv:2607. 00127v1 Announce Type: new Abstract: Survival analysis models time-to-event data, but in clinical settings training data are costly and scarce: events accrue over years of follow-up, cohorts are small, and privacy regulations restrict sharing across institutions.

arXiv Machine Learning
Aug 14

CoMedBench: A Multi-Source Benchmark of Synthetic Medical Data Fidelity and Downstream Utility

arXiv:2608. 12805v1 Announce Type: new Abstract: Access to clinical data is essential for developing reliable healthcare machine learning systems, but direct use of electronic health records is constrained by privacy regulation, institutional review, data-use agreements, and the risk of re-identification.

By Akanta Das, Al Amin Farhad, Mrinmoy Sarkar Anto, David Rehkopf, Ayin Vala, Tanmoy Sarkar Pias
arXiv AI
Jul 23

Recovering Clinical Utility Under Differential Privacy: Empirical Validation of Adaptive Federated Aggregation on Heterogeneous Cardiovascular Datasets

arXiv:2607. 19403v1 Announce Type: cross Abstract: Validating federated learning frameworks on real clinical data is an essential step between proof-of-concept demonstrations in controlled synthetic environments and deployment in real multicenter healthcare settings.

By Rodrigo Tertulino, Laercio Alencar, Ricardo Almeida
arXiv Machine Learning
Jun 24

Federated Survival Analysis in Healthcare: A Multi-Model Evaluation on Cross-Institutional Heterogeneous Breast Cancer Data

arXiv:2606. 23871v1 Announce Type: new Abstract: Survival analysis is central to clinical decision-making, yet reliable time-to-event models require large, diverse cohorts that are rarely available at a single institution, while privacy regulations restrict the centralization of patient data.

By Natalia Moreno-Blasco, Anusha Ihalapathirana, Pekka Siirtola, Miguel Fernandez-de-Retana
arXiv AI
Jul 23

SynPre-FL: Synthetic data-driven pretraining integrated Federated Learning training framework

arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.

By Akarsh K Nair, Muhammad Arifur Rahman, Nicholas Shopland, Andy Burton, Jun He, Yuan Shen, David Baldwin, Emma O'Dowd, Amna Burzic, Mufti Mahmud, David J. Brown
arXiv AI
Jul 17

Demographically-Conditioned Synthetic Medical Images for Bias Mitigation and Bias Detection in Disease Classifiers

arXiv:2607. 14984v1 Announce Type: new Abstract: Per-subgroup fairness audits of medical image classifiers face a sample-size problem: minority subgroups in held-out test sets have so few samples that the resulting confidence intervals on per-subgroup performance are wider than the bias the audit is meant to detect.

By Mahmoud Ibrahim, Bart Elen, Chang Sun, Gokhan Ertaylan, Michel Dumontier
arXiv AI
Aug 21

Drift-Adaptive ICU Intervention Prediction: Freezing the Physiological Encoder for Auditable Model Updating

arXiv:2607. 19020v2 Announce Type: replace-cross Abstract: Clinical decision support degrades as treatment protocols evolve, but the obstacle to updating a deployed model is governance as much as accuracy: once retraining touches every parameter, no one can say afterwards where the update acted.

By Fatema Ferdous Tamanna, K. M. Merajul Arefin, Md. Abdul Masud
arXiv Machine Learning
Jun 4

SurvPFN: Towards Foundation Models for Survival Predictions

arXiv:2606. 04564v1 Announce Type: new Abstract: Tabular foundation models (TFMs) have made rapid progress in standard classification and regression, but time-to-event survival prediction tasks have remained largely untouched.

By Samuel B\"ohm (Institute of Epidemiology and Prevention, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany), Lennart Purucker (Department of Computer Science, University of Freiburg, Freiburg, Germany, PriorLabs, Freiburg, Germany), Frank Hutter (Department of Computer Science, University of Freiburg, Freiburg, Germany, PriorLabs, Freiburg, Germany), Pascal Schlosser (Institute of Epidemiology and Prevention, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, US, CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany)
arXiv AI
Sep 7

Adaptation Interfaces for In-Context Tabular Foundation Models in Time-to-Event Prediction

The paper explores how to adapt tabular foundation models (TabFMs) for censored time‑to‑event prediction by linking them with CoxPH and DeepHit and revising training procedures. It evaluates zero‑shot, classification‑based fine‑tuning, and survival‑head adaptations across 74 single‑risk and 4 competing‑risk datasets, finding that zero‑shot works best on small datasets while supervised adaptation excels as data grows. The study shows that the choice of adaptation interface and data regime critically influences TabFM transfer performance.

By Minh-Khoi Pham, Luca Cotugno, Dan Cernei, Alina Sirbu, Stefano Masi, Giuseppe Prencipe, Alessandro Pingitore, Patrizia Landi, Working Group on Uric Acid, Cardiovascular Risk of the Italian Society of Hypertension, Tai Tan Mai, Martin Crane, Marija Bezbradica
arXiv Machine Learning
Sep 21

Available Guardrails: Certifying Selective Prediction across ML Systems

The paper introduces a method to certify selective prediction in machine learning systems by computing the availability of safety gates through exact-binomial inversion and dynamic programming. It demonstrates that a truth-informed planner can significantly improve mean coverage over naive approaches, and that reallocating error budgets further enhances coverage across diverse applications such as LLM tool‑calling, content moderation, lesion classification, and recommendation. The study highlights the importance of planning and finite‑sample estimation in ensuring reliable, granular deployment of selective predictors.

By Parivesh Priye, Yufeng Wang, Haibin Ling, Michael Chaykowsky