arXiv:2508. 10017v2 Announce Type: replace-cross Abstract: Federated Learning (FL) presents a groundbreaking approach for collaborative health research, allowing model training on decentralized data while safeguarding patient privacy.
arXiv:2607. 19403v1 Announce Type: cross Abstract: Validating federated learning frameworks on real clinical data is an essential step between proof-of-concept demonstrations in controlled synthetic environments and deployment in real multicenter healthcare settings.
arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.
arXiv:2509. 10517v3 Announce Type: replace Abstract: Machine learning can predict in-hospital mortality, but data privacy and the statistical heterogeneity of clinical data hamper its use.
arXiv:2607. 08595v1 Announce Type: new Abstract: Cardiovascular disease risk prediction models often rely on data from a single institution or centrally pooled datasets.
arXiv:2606. 04338v1 Announce Type: new Abstract: Privacy-sensitive and distributed characteristics of multi-center medical data bring severe obstacles to centralized modeling for accurate early prediction of sepsis.
Privacy-sensitive and distributed characteristics of multi-center medical data bring severe obstacles to centralized modeling for accurate early prediction of sepsis. Federated learning (FL) has attracted growing attention as a promising framework for collaborative model development, as it allows multiple institutions to jointly train predictive models without directly sharing or centralizing raw data.
The paper introduces DP‑BR‑FedAvg, a federated learning framework that combines Gaussian‑mechanism differential privacy with a coordinate‑wise trimmed‑mean Byzantine‑robust aggregation rule. It is evaluated on a simulated cross‑institutional classification task involving fraud and clinical‑risk scoring, where it improves the F1‑score for a minority class from 0.030 (plain FedAvg) to 0.119 while bounding privacy loss. The study demonstrates that privacy and robustness mechanisms interact, and that system design for regulated, adversarial, cross‑institutional settings must account for this interaction.
The paper introduces DP‑BR‑FedAvg, a federated learning framework that combines Gaussian‑mechanism differential privacy with a coordinate‑wise trimmed‑mean Byzantine‑robust aggregation rule. It is evaluated on a simulated cross‑institutional classification task for fraud and clinical‑risk scoring, showing that plain FedAvg fails when a quarter of twenty clients are Byzantine, while DP‑BR‑FedAvg recovers more signal and bounds privacy loss. The study demonstrates that privacy and robustness interact, and system design for regulated, adversarial, cross‑institutional settings must account for this interaction.
Aegis is a client‑side defense for medical federated learning that protects against model inversion attacks by adding a masking gradient derived from locally synthesized data. The method exploits the fact that attacks fail when the effective batch size exceeds the model’s leakage capacity, turning this bottleneck into a privacy guarantee. Experiments on MNIST, CIFAR‑10, and MedMNIST datasets show that Aegis neutralizes state‑of‑the‑art attacks while preserving model accuracy and adding only modest overhead.
GRIN+ is a new machine unlearning framework that targets fast and precise data erasure in imbalanced medical datasets. It separates unlearning‑specific knowledge from general representations by analyzing gradient contributions of forget and retain sets, introduces a class‑adaptive influence scoring to counter gradient dominance, and uses a direction‑constrained update to protect essential clinical knowledge. Benchmarks on skin cancer, brain tumor, and breast ultrasound data show that GRIN+ balances privacy, efficiency, and utility, achieving high diagnostic accuracy and faster runtime than existing methods.
arXiv:2606. 18518v1 Announce Type: cross Abstract: The development of medical AI is constrained by limited access to high-quality clinical data due to institutional silos and strict privacy regulations such as HIPAA and GDPR.
arXiv:2502. 17748v4 Announce Type: replace Abstract: Federated Learning (FL) inherently mitigates mass data centralization risks; however, its privacy protections are not equally distributed - leaving vulnerable individuals disproportionately exposed to sophisticated privacy attacks.