arXiv:2601. 22324v3 Announce Type: replace Abstract: Modern clinical practice relies on evidence-based guidelines implemented as compact scoring systems composed of a small number of interpretable decision rules.
arXiv:2606. 16337v1 Announce Type: new Abstract: Predictive modeling for clinical tabular data is central to clinical decision support and therefore requires not only strong predictive performance but also transparent decision logic.
arXiv:2606. 14149v1 Announce Type: new Abstract: Large Language Models (LLMs) are increasingly deployed in healthcare settings, yet their tendency to hallucinate poses risks when clinical decisions are involved.
arXiv:2608. 05375v1 Announce Type: new Abstract: Clinical machine learning (ML) has the potential to support high-stakes medical decision-making, but reliable deployment is often constrained by scarce, heterogeneous, and temporal complexity.
arXiv:2608.30022v1 Announce Type: new Abstract: Introduction: NICE guidelines provide evidence-based recommendations for clinical care but remain largely in unstructured natural language. Existing ap...
arXiv:2607. 15394v1 Announce Type: new Abstract: Black-box models limit the adoption of artificial intelligence in medicine due to their lack of interpretability and reproducibility.
arXiv:2602. 19502v2 Announce Type: replace Abstract: Agentic AI systems are increasingly capable of autonomous data science workflows, yet clinical prediction tasks demand domain expertise that purely automated approaches struggle to provide.
The paper introduces a statistically grounded framework for interpretable, rule-based clinical classification using Bernoulli Naïve Bayes (BNB). It employs supervised chi‑square‑guided binarization to convert continuous medical variables into binary indicators, enabling BNB to handle continuous data while maintaining transparency. On three benchmark datasets—Pima Indians Diabetes, Wisconsin Breast Cancer, and Heart Failure Prediction—the method achieved AUCs of 0.800, 0.984, and 0.919, respectively, and demonstrated reliable probability calibration through cross‑validated analysis and post‑hoc beta calibration.
arXiv:2604. 09737v2 Announce Type: replace-cross Abstract: Structured prediction with large language models requires outputs that are label-accurate, ontology-constrained, structurally valid, and evidence-grounded under label imbalance and heterogeneous group difficulty.
arXiv:2606. 20208v1 Announce Type: new Abstract: Machine learning models are predominantly evaluated through predictive performance metrics such as ranking quality, prediction error, or classification accuracy.
arXiv:2510. 17532v2 Announce Type: replace-cross Abstract: Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data.
The paper introduces a four-step pipeline that mines decision rules in the latent space of an FT-Transformer and then translates those rules back into measurable clinical features. By treating embedding dimensions that separate patient groups as latent biomarkers, small decision trees are used to extract rules, which are then mapped to raw features using gradient-input saliency and CLS attention attribution. Across six public clinical datasets, the translated rules generally outperformed raw-feature rules, achieving significant AUROC gains, though some high-performing latent rules could not be fully captured by simple raw-feature conditions.
arXiv:2603.02221v3 Announce Type: replace-cross Abstract: In clinical tabular prediction, classical machine learning models with feature engineering often outperform neural methods. LLMs are increasi...