Annotation quality is a major bottleneck in building reliable and explainable artificial intelligence (XAI) systems for mental health research. In depression-related datasets, labels are often assigned without structured evidence, symptom-level justification, or traceable alignment with the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR), limiting both transparency and downstream model interpretability.
arXiv:2607. 25681v1 Announce Type: new Abstract: Cognitive distortion amplifies negative emotions and contributes to mental health disorders.
By Qi Chen, Siria Xiyueyao Luo, Jian Wang, Yuan Shi, Haocong Rao, Xuejiao Zhao
arXiv:2606. 10796v1 Announce Type: cross Abstract: Automatic Depression Detection (ADD) from clinical interviews is a pivotal task in computational mental health, yet it remains challenging due to two critical obstacles: 1) difficulty in modeling complex but sparsely distributed depression clues within lengthy, multi-topic clinical interviews, leading to superficial and unreliable reasoning; 2) scarcity of labeled data due to clinical privacy, together with high cost of training and fine-tuning, limiting the deployment of supervised ADD systems.
By Yiqing Lyu, Xianbing Zhao, Buzhou Tang, Ronghuan Jiang
arXiv:2512. 06227v3 Announce Type: replace-cross Abstract: Real-world indicators play an important role in many Natural Language Processing (NLP) applications, such as life events for mental health analysis and risky behaviours for online safety, yet labelling such information is often costly and/or difficult due to its multi-label and dynamic nature.
By Junyu Mao, Anthony Hills, Talia Tseriotou, Maria Liakata, Aya Shamir, Dan Sayda, Dana Atzil-Slonim, Natalie Djohari, Pamela Ugwudike, Mahesan Niranjan, Stuart E. Middleton
arXiv:2607. 13036v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly used for decision support in healthcare, but clinical evidence is often incomplete or evolving.
By Oriana Presacan, Andreea Grama, Larisa Irimin\u{a}, Alireza Nik, Jaya Ojha, Vajira Thambawita, Ciprian I. B\u{a}cil\u{a}, Bogdan Ionescu, Michael A. Riegler
arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.
By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang
arXiv:2608. 12329v1 Announce Type: cross Abstract: Progress on AI for psychosis-risk assessment is limited by a data-access bottleneck.
By Guilherme C. Oliveira, Stephanie Fong, Zimu Wang, Clarice Lee, Xiangyu Zhao, Duy Khoa Pham, Duong Nhu, Yiwen Jiang, Jiahe Liu, Zhongxing Xu, Dwarikanath Mahapatra, Dominic Dwyer, Zongyuan Ge
arXiv:2605. 01189v2 Announce Type: replace Abstract: Clinical AI adoption is hindered by the black-box/grey-box nature of high-performing models, which lack the ontological grounding and narrative transparency required for professional-level explainability.
By Anuradha Chandrasekaran, Dimitrios Zikos, Mutlu Mete, Alan Pang, Brady D. Lund, Kewei Sha
arXiv:2604. 09737v2 Announce Type: replace-cross Abstract: Structured prediction with large language models requires outputs that are label-accurate, ontology-constrained, structurally valid, and evidence-grounded under label imbalance and heterogeneous group difficulty.
By Samah Fodeh, Ganesh Puthiaraju, Elyas Irankhah, Afshan Khan, Sreeraj Ramachandran, Linhai Ma, Srivani Talakokkul, Sarah Schellhorn
arXiv:2508. 16674v2 Announce Type: replace-cross Abstract: Medical report understanding from real-world document images is essential for generating patient-facing explanations and enabling structured information exchange in clinical systems.
By Fangxin Shang, Yuan Xia, Dalu Yang, Yahui Wang, Binglin Yang
arXiv:2607. 20462v1 Announce Type: new Abstract: Large language models (LLMs) are increasingly integrated into clinical workflows, stressing the need for reliable traceability of model-generated output with watermarking.
By Melanie Rieff, Robin Staab, Thibaud Gloaguen, Stefan Hegselmann, Martin Vechev
arXiv:2607. 12886v1 Announce Type: new Abstract: Clinical notes contain many of the signs and symptoms that bring patients to care, yet this information rarely reaches structured fields.
By Cameron Cagan, Pedram Fard, Jiazi Tian, Jingya Cheng, Shawn N. Murphy, Hossein Estiri