The study investigates how a large language model, Gemma-3-27B-PT, internally represents depressive symptoms. By applying mechanistic interpretability methods to the model’s residual stream, researchers found that symptom groups are geometrically distinct at layer 21, and that projected symptom vectors align with clinician-annotated rankings across mood, somatic, and suicidality dimensions. Additionally, a single depression vector at this layer can differentiate depressive from non-depressive text with an AUC of 0.789, suggesting a potential emotional valence gate for symptom projection.
By Fangyi Zhu, Ajay Subramanian, Allison Constant, Camille Wang, Ravish Gupta, Corey J. Keller
LongCounsel-8 is a new benchmark suite comprising three datasets with 7,749 five‑session counseling dialogues, each grounded in real client profiles, depression trajectories, symptom compositions, and counseling patterns. The benchmark addresses challenges of longitudinal consistency, empirical grounding of symptom progression, and natural expression of controlled depression states without exposing labels. Experiments show that lower single‑session error does not ensure accurate trend detection, methods perform worse on worsening trajectories, and adding more session history can reduce trend prediction accuracy.
By Jiayi Li, Zhaomin Wu, Bingsheng He
The paper examines automatic depression detection from doctor‑patient conversations and finds that models trained on semi‑structured interview data can achieve high accuracy by exploiting fixed interviewer prompts rather than the participants’ language. Across three datasets (ANDROIDS, DAIC‑WOZ, E‑DAIC), the authors show that restricting models to participant utterances distributes decision evidence more broadly and reflects genuine linguistic cues. The study highlights a cross‑dataset, architecture‑agnostic bias introduced by interviewer prompts and calls for analyses that localize decision evidence by time and speaker to ensure models learn from participants’ language.
By Hasindri Watawana, Sergio Burdisso, Diego A. Moreno-Galv\'an, Fernando S\'anchez-Vega, A. Pastor L\'opez-Monroy, Petr Motlicek, Esa\'u Villatoro-Tello
arXiv:2607. 15202v1 Announce Type: new Abstract: Annotation quality is a major bottleneck in building reliable and explainable artificial intelligence (XAI) systems for mental health research.
By Hoang-Loc Cao, Van Pham, Truong Thanh Hung Nguyen, Phuc Truong Loc Nguyen, Phuc Ho, Veronica Whitford, Hung Cao
The paper introduces a two‑stage framework for recognizing depression symptoms at the sentence level. First, a contrastively fine‑tuned sentence encoder generates a symptom candidate for each sentence. Then, a fine‑tuned language model verifies the candidate’s presence or absence by comparing the sentence, its context, and a diagnostic definition, ensuring the model’s judgment aligns with that definition before responding.
By Weiming Li, Catarina Barata, Miguel Constante, Joao Sanches
arXiv:2605.22286v2 Announce Type: replace-cross
Abstract: Text-based counseling provides a valuable source of information for assessing depression severity. We study prediction of the total score on...
By Zhaomin Wu, Jiayi Li, Bingsheng He
LongCounsel-8 is a benchmark suite comprising three independently generated datasets with 7,749 five‑session counseling trajectories, designed to evaluate longitudinal depression tracking. The datasets are grounded in real‑world client profiles, depression trajectories, symptom compositions, and counseling patterns, and they address challenges of longitudinal consistency, empirical grounding, and natural expression of controlled depression states. Experiments show that lower single‑session error does not guarantee accurate trend identification, that methods perform worse on worsening trajectories, and that adding more session history can reduce trend prediction accuracy.
Annotation quality is a major bottleneck in building reliable and explainable artificial intelligence (XAI) systems for mental health research. In depression-related datasets, labels are often assigned without structured evidence, symptom-level justification, or traceable alignment with the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR), limiting both transparency and downstream model interpretability.
arXiv:2606.17973v2 Announce Type: replace
Abstract: Depression is a leading cause of disability worldwide, yet validated questionnaires such as the Patient Health Questionnaire-9 (PHQ-9) often go unc...
By Olivier Tieleman, Samuel J. Bell, Ziyi Zhu, Ting Su, Elizabeth Kroll, Thomas D. Hull, Caitlin A. Stamatis
The paper introduces the first benchmark for evaluating confidence estimation in large language models during multi‑turn medical consultations, combining three types of medical data and an information sufficiency gradient to capture how confidence and correctness evolve as evidence accumulates. Experiments with 27 methods reveal that token‑level and consistency‑level confidence approaches are limited by medical data, and that medical reasoning must be judged on both diagnostic accuracy and information completeness. Building on these findings, the authors propose MedConf, a retrieval‑augmented, linguistically grounded self‑assessment framework that aligns patient information with supporting, missing, and contradictory relations, producing interpretable confidence estimates that outperform existing methods across multiple datasets and LLMs.
By Zhiyao Ren, Yibing Zhan, Siyuan Liang, Guozheng Ma, Baosheng Yu, Dacheng Tao
arXiv:2501. 16106v2 Announce Type: replace Abstract: Recent advances in multimodal depression recognition for clinical interviews (MDRC) have demonstrated the potential of AI systems by integrating textual, acoustic, and facial cues.
By Wenjie Zheng, Qiming Xie, Jianfei Yu, Yang Wang, Lei Cao, Fei Wang, Shijin Wang, Rui Xia, Chengqing Zong
arXiv:2608. 08746v1 Announce Type: new Abstract: Prospective daily symptom tracking is central to premenstrual health assessment, but repeated ordinal forms impose substantial response burden.
By Yifan Wang