arXiv:2607. 15202v1 Announce Type: new Abstract: Annotation quality is a major bottleneck in building reliable and explainable artificial intelligence (XAI) systems for mental health research.
By Hoang-Loc Cao, Van Pham, Truong Thanh Hung Nguyen, Phuc Truong Loc Nguyen, Phuc Ho, Veronica Whitford, Hung Cao
Annotation quality is a major bottleneck in building reliable and explainable artificial intelligence (XAI) systems for mental health research. In depression-related datasets, labels are often assigned without structured evidence, symptom-level justification, or traceable alignment with the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR), limiting both transparency and downstream model interpretability.
The study investigates how a large language model, Gemma-3-27B-PT, internally represents depressive symptoms. By applying mechanistic interpretability methods to the model’s residual stream, researchers found that symptom groups are geometrically distinct at layer 21, and that projected symptom vectors align with clinician-annotated rankings across mood, somatic, and suicidality dimensions. Additionally, a single depression vector at this layer can differentiate depressive from non-depressive text with an AUC of 0.789, suggesting a potential emotional valence gate for symptom projection.
By Fangyi Zhu, Ajay Subramanian, Allison Constant, Camille Wang, Ravish Gupta, Corey J. Keller
arXiv:2608.29582v1 Announce Type: cross
Abstract: Current evaluations of large language models (LLMs) primarily focus on factual knowledge retrieval, overlooking the fundamental challenge of navigati...
By Yi Yu, Bo Wang, Chong Feng, Ge Shi, Xia Liu, Ziyi Yang, Xuewen Shi
arXiv:2511.07011v2 Announce Type: replace-cross
Abstract: Background: Remotely captured spoken language could provide objective, regular indicators of depression symptom severity. However, research t...
By Anastasiia Tokareva, Judith Dineley, Zoe Firth, Pauline Conde, Faith Matcham, Sara Siddi, Femke Lamers, Ewan Carr, Carolin Oetzmann, Daniel Leightley, Yuezhou Zhang, Amos A. Folarin, Josep Maria Haro, Brenda W. J. H. Penninx, Raquel Bailon, Srinivasan Vairavan, Til Wykes, Richard J. B. Dobson, Vaibhav A. Narayan, Matthew Hotopf, Nicholas Cummins, The RADAR-CNS Consortium
arXiv:2501. 16106v2 Announce Type: replace Abstract: Recent advances in multimodal depression recognition for clinical interviews (MDRC) have demonstrated the potential of AI systems by integrating textual, acoustic, and facial cues.
By Wenjie Zheng, Qiming Xie, Jianfei Yu, Yang Wang, Lei Cao, Fei Wang, Shijin Wang, Rui Xia, Chengqing Zong
arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.
By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang
MTDiag is a newly released multi-turn diagnostic dialogue dataset designed to evaluate large language models (LLMs) in clinically meaningful ways. It is built from DDXPlus, MIMIC-IV, and AJCR case reports, covering both common emergency department presentations and rare conditions, and normalizes cases into a canonical schema using UMLS concept identifiers and ICD-10 codes. The dataset includes a UserLM‑8B utterance‑generation pipeline and physician‑validated natural‑language utterances, and introduces clinical knowledge‑grounded metrics that go beyond simple diagnostic accuracy for multi‑turn differential diagnosis tasks.
By Pia Chouayfati, Alexander M. Fichtl, Miriam Ansch\"utz, George Doumat, Georg Groh
arXiv:2608. 16643v1 Announce Type: cross Abstract: Automated detection of errors in clinical documentation is a promising application of large language models (LLMs), yet decisions to deploy such models rest on benchmarks that evaluate each clinical note in isolation.
By Yifan Zhang, Rahmatollah Beheshti
arXiv:2606. 10796v1 Announce Type: cross Abstract: Automatic Depression Detection (ADD) from clinical interviews is a pivotal task in computational mental health, yet it remains challenging due to two critical obstacles: 1) difficulty in modeling complex but sparsely distributed depression clues within lengthy, multi-topic clinical interviews, leading to superficial and unreliable reasoning; 2) scarcity of labeled data due to clinical privacy, together with high cost of training and fine-tuning, limiting the deployment of supervised ADD systems.
By Yiqing Lyu, Xianbing Zhao, Buzhou Tang, Ronghuan Jiang
arXiv:2607. 12886v1 Announce Type: new Abstract: Clinical notes contain many of the signs and symptoms that bring patients to care, yet this information rarely reaches structured fields.
By Cameron Cagan, Pedram Fard, Jiazi Tian, Jingya Cheng, Shawn N. Murphy, Hossein Estiri
arXiv:2601.16753v2 Announce Type: replace-cross
Abstract: Longitudinal information in radiology reports refers to the sequential tracking of findings across multiple examinations over time, which is...
By Xinyi Wang, Grazziela Figueredo, Ruizhe Li, Xin Chen