arXiv:2607. 15202v1 Announce Type: new Abstract: Annotation quality is a major bottleneck in building reliable and explainable artificial intelligence (XAI) systems for mental health research.
By Hoang-Loc Cao, Van Pham, Truong Thanh Hung Nguyen, Phuc Truong Loc Nguyen, Phuc Ho, Veronica Whitford, Hung Cao
Annotation quality is a major bottleneck in building reliable and explainable artificial intelligence (XAI) systems for mental health research. In depression-related datasets, labels are often assigned without structured evidence, symptom-level justification, or traceable alignment with the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR), limiting both transparency and downstream model interpretability.
The study investigates how a large language model, Gemma-3-27B-PT, internally represents depressive symptoms. By applying mechanistic interpretability methods to the model’s residual stream, researchers found that symptom groups are geometrically distinct at layer 21, and that projected symptom vectors align with clinician-annotated rankings across mood, somatic, and suicidality dimensions. Additionally, a single depression vector at this layer can differentiate depressive from non-depressive text with an AUC of 0.789, suggesting a potential emotional valence gate for symptom projection.
By Fangyi Zhu, Ajay Subramanian, Allison Constant, Camille Wang, Ravish Gupta, Corey J. Keller
arXiv:2605.22286v2 Announce Type: replace-cross
Abstract: Text-based counseling provides a valuable source of information for assessing depression severity. We study prediction of the total score on...
By Zhaomin Wu, Jiayi Li, Bingsheng He
arXiv:2608.29582v1 Announce Type: cross
Abstract: Current evaluations of large language models (LLMs) primarily focus on factual knowledge retrieval, overlooking the fundamental challenge of navigati...
By Yi Yu, Bo Wang, Chong Feng, Ge Shi, Xia Liu, Ziyi Yang, Xuewen Shi
arXiv:2511.07011v2 Announce Type: replace-cross
Abstract: Background: Remotely captured spoken language could provide objective, regular indicators of depression symptom severity. However, research t...
By Anastasiia Tokareva, Judith Dineley, Zoe Firth, Pauline Conde, Faith Matcham, Sara Siddi, Femke Lamers, Ewan Carr, Carolin Oetzmann, Daniel Leightley, Yuezhou Zhang, Amos A. Folarin, Josep Maria Haro, Brenda W. J. H. Penninx, Raquel Bailon, Srinivasan Vairavan, Til Wykes, Richard J. B. Dobson, Vaibhav A. Narayan, Matthew Hotopf, Nicholas Cummins, The RADAR-CNS Consortium
arXiv:2501. 16106v2 Announce Type: replace Abstract: Recent advances in multimodal depression recognition for clinical interviews (MDRC) have demonstrated the potential of AI systems by integrating textual, acoustic, and facial cues.
By Wenjie Zheng, Qiming Xie, Jianfei Yu, Yang Wang, Lei Cao, Fei Wang, Shijin Wang, Rui Xia, Chengqing Zong
The paper examines automatic depression detection from doctor‑patient conversations and finds that models trained on semi‑structured interview data can achieve high accuracy by exploiting fixed interviewer prompts rather than the participants’ language. Across three datasets (ANDROIDS, DAIC‑WOZ, E‑DAIC), the authors show that restricting models to participant utterances distributes decision evidence more broadly and reflects genuine linguistic cues. The study highlights a cross‑dataset, architecture‑agnostic bias introduced by interviewer prompts and calls for analyses that localize decision evidence by time and speaker to ensure models learn from participants’ language.
By Hasindri Watawana, Sergio Burdisso, Diego A. Moreno-Galv\'an, Fernando S\'anchez-Vega, A. Pastor L\'opez-Monroy, Petr Motlicek, Esa\'u Villatoro-Tello
arXiv:2604.27846v2 Announce Type: replace
Abstract: How people narrate their experiences offers a window into how the mind organizes them. Computational approaches to therapeutic writing have evolved...
By Yuxi Ma, Jieming Cui, Muyang Li, Ye Zhao, Yu Li, Yixuan Wang, Chi Zhang, Yinyin Zang, Yixin Zhu
arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.
By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang
MTDiag is a newly released multi-turn diagnostic dialogue dataset designed to evaluate large language models (LLMs) in clinically meaningful ways. It is built from DDXPlus, MIMIC-IV, and AJCR case reports, covering both common emergency department presentations and rare conditions, and normalizes cases into a canonical schema using UMLS concept identifiers and ICD-10 codes. The dataset includes a UserLM‑8B utterance‑generation pipeline and physician‑validated natural‑language utterances, and introduces clinical knowledge‑grounded metrics that go beyond simple diagnostic accuracy for multi‑turn differential diagnosis tasks.
By Pia Chouayfati, Alexander M. Fichtl, Miriam Ansch\"utz, George Doumat, Georg Groh
arXiv:2608. 16643v1 Announce Type: cross Abstract: Automated detection of errors in clinical documentation is a promising application of large language models (LLMs), yet decisions to deploy such models rest on benchmarks that evaluate each clinical note in isolation.
By Yifan Zhang, Rahmatollah Beheshti