arXiv Computation and Language

Beyond Empathy: Integrating Diagnostic and Therapeutic Reasoning with Large Language Models for Mental Health Counseling

The paper introduces PsyLLM, a large language model specifically designed for mental health counseling that integrates diagnostic reasoning and multiple therapeutic frameworks. It employs an automated data synthesis pipeline that transforms Reddit mental‑health posts into multi‑turn counseling dialogues, guided by DSM/ICD standards and therapies such as CBT, ACT, and psychodynamic approaches. A new benchmark and evaluation protocol show that PsyLLM outperforms baseline models, with results validated by professional counseling experts.

arXiv Computation and Language
Sep 1

Graph2Counsel: Clinically Grounded Synthetic Counseling Dialogue Generation from Client Psychological Graphs

Graph2Counsel is a framework that generates synthetic counseling dialogues by leveraging Client Psychological Graphs (CPGs) to encode the relationships among a client’s thoughts, emotions, and behaviors. The system uses a structured prompting pipeline guided by counselor strategies and explores techniques such as Chain‑of‑Thought and Multi‑Agent Feedback to produce 760 realistic sessions from 76 CPGs. Expert evaluation shows the dataset surpasses previous ones in specificity, counselor competence, authenticity, conversational flow, and safety, and fine‑tuning an open‑source model on it improves performance on several counseling benchmarks.

By Aishik Mandal, Hiba Arnaout, Clarissa W. Ong, Juliet Bockhorst, Kate Sheehan, Rachael Moldow, Tanmoy Chakraborty, Iryna Gurevych
arXiv Computation and Language
Aug 31

Roleplaying with Structure: Synthetic Therapist-Client Conversation Generation from Questionnaires

arXiv:2510.25384v2 Announce Type: replace Abstract: Large Language Models (LLMs) are promising tools for synthetic data generation in mental health. However, privacy policies and restrictions forced...

By Doan Nam Long Vu, Rui Tan, Lena Moench, Svenja Jule Francke, Daniel Woiwod, Florian Thomas-Odenthal, Sanna Stroth, Tilo Kircher, Christiane Hermann, Udo Dannlowski, Hamidreza Jamalabadi, Simone Balloccu, Shaoxiong Ji
arXiv Computation and Language
Sep 23

From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Health

The article surveys how large language models (LLMs) are being applied to mental health, outlining a three‑phase evolution: Phase I uses LLMs as passive information tools and pattern recognizers for assessment; Phase II employs them as empathetic conversationalists for stateless, in‑the‑moment interactions; Phase III aims to create longitudinal, personalized companions that act as stateful cognitive agents. It systematically reviews core technologies, agent architectures (Profile, Memory, Reasoning, Planning), and the datasets and benchmarks that support this progression, offering a coherent narrative and roadmap for future research. The survey also provides a curated resource list at https://github.com/Emo-gml/Awesome-Mental-Health-LLMs.

By He Hu, Yucheng Zhou, Qianning Wang, Yingjian Zou, Chiyuan Ma, Juzheng Si, Jianzhuang Liu, Zitong Yu, Laizhong Cui, Fei Ma, Qi Tian
arXiv Computation and Language
Oct 16

MindEval2: Clinically Grounded Patients and Rubrics for Evaluating Language Models in Mental Health Support

MindEval2 is a new evaluation framework for AI chatbots in mental health support, comprising Mental Health Quality Rubrics (MHQR) and the MindSim patient simulation harness. MHQR, developed with PhD-level psychologists, provides explicit, actionable criteria for assessing response quality, while MindSim offers realistic, longitudinal patient interactions with a memory component. The study evaluated 18 models, finding that although surface-level quality has improved, guidance calibration remains the main failure across all models.

By John Mendon\c{c}a, Daniel Tschernutter, Jos\'e Pombal, Areti Vassilopoulos, Catarina Botelho, Ignacio Sarasua, Maya D'Eon, Nuno Guerreiro, Ricardo Rei
arXiv AI
Aug 20

Large Language Models in Mental Health: A Systematic Review of Applications, Innovations, and Ethical Challenges

The paper reviews how large language models are applied in mental health, covering areas such as social media analysis, clinical conversational agents, therapy support tools, prompt engineering, and multimodal learning. It synthesizes interdisciplinary studies that use social media posts, electronic medical records, and multimodal inputs to detect depression, assess suicide risk, provide personalized therapy, and generate psychoeducational content. The review also discusses advances in model interpretability, annotation strategies, multimodal fusion techniques, and highlights ethical, sociotechnical, and regulatory challenges while proposing frameworks for safe, equitable, and accountable deployment.

By Yisong Chen, Yifan Gao, Sijing Yu, Chuqing Zhao, Yang Lu
arXiv AI
Oct 31

PromptSense: Sentiment-Aware Mental Health Chatbot with Dynamic Prompting

PromptSense introduces a sentiment‑aware mental health chatbot that incorporates sentiment and depression analysis with rule‑based filtering before model inference. By dynamically constructing prompts from emotional and risk insights, the system enhances contextual relevance, empathy, and safety of responses. Experiments across four model strategies and two prompt variants show that the engineered prompts outperform DSFT and RLAIF by 1.8% and 1.1% on qualitative metrics and toxicity assessments.

By Sugi Lee, Jianlong Zhou, Jing sUN
arXiv AI
2d ago

TherapyGym: Evaluating and Aligning Clinical Fidelity and Safety in Therapy Chatbots

arXiv:2603.18008v2 Announce Type: replace-cross Abstract: Large language models (LLMs) are increasingly used for mental-health support; yet prevailing evaluation methods--fluency metrics, preference...

By Fangrui Huang, Souhad Chbeir, Arpandeep Khatua, Sheng Wang, Sijun Tan, Kenan Ye, Lily Bailey, Merryn Daniel, Ryan Louie, Sanmi Koyejo, Ehsan Adeli
arXiv AI
Jun 3

ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning

arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).

By Bo-Hong Wang, Baicheng Peng, Ruilin Wang, Jun Bai, Ziyang Song, Yue Li
arXiv Computation and Language
Oct 23

PsyCLIENT: Client Simulation via Conversational Trajectory Modeling for Trainee Practice and Model Evaluation in Mental Health Counseling

PsyCLIENT is a framework that uses large language models to simulate counseling clients by conditioning responses on client profiles, dialogue histories, and conversational trajectories that specify target behaviors and content constraints. The authors created PsyCLIENT-CP, a dataset of 120 Chinese client profiles covering 60 counseling topics, and evaluated the system with 24 professional counselors, finding higher authenticity and training utility ratings compared to baseline methods. In a source-identification study, PsyCLIENT-generated dialogues were more often mistaken for real human-client interactions than those from other models, indicating the effectiveness of conversational trajectory modeling in producing realistic counseling conversations.

By Huachuan Qiu, Zhaoming Chen, Yuqian Chen, Yuan Xie, Yu Lu, Zhenzhong Lan
arXiv AI
Aug 26

When Less Is More: An Empirical Study of Minimal Responses in Counseling Dialogues and the Behavior of LLMs

The paper investigates the role of minimal responses—short, empathic utterances—in psychological counseling, noting that such brief replies are common in human dialogues but underrepresented in large language model (LLM) outputs. Using a two‑stage filtering approach and contextual verification with an LLM, the authors systematically analyze minimal responses across multiple counseling datasets. They find that while strong commercial LLMs can produce minimal replies when prompted, they often fail to judge when these replies are appropriate, and counseling‑specific models trained on synthetic data tend to generate longer, content‑rich responses instead.

By Zhiyang Qi
arXiv AI
Sep 25

BiGraph-Diffuse: A Bidirectional Diffusion Language Model with Graph-Structured Retrieval For Mental Health Counseling

BiGraph-Diffuse is a large‑scale diffusion language model designed for mental health counseling, addressing two key limitations of existing AI dialogue systems: the lack of bidirectional understanding for progressive disclosure and the inadequate use of relational clinical knowledge. It pairs this diffusion model with BiGraph‑RAG, a graph‑structured retrieval approach that uses lightweight entity extraction and semantic linking to preserve inferential pathways from symptoms to underlying causes without incurring LLM token costs during indexing. Experiments and theoretical analysis demonstrate the effectiveness of this mutually reinforcing architecture.

By Yuxiang Cheng, Quanwei Tang, Lvhui Lu, Dong Zhang, Shoushan Li, Erik Cambria