arXiv:2606. 06869v1 Announce Type: new Abstract: Aim: Existing AI-assisted traditional Chinese medicine diagnostic tools suffer from opaque reasoning processes, passive interaction, and limited treatment plan presentation.
arXiv:2606. 20164v1 Announce Type: cross Abstract: Real-world clinical decision support requires reasoning over heterogeneous and longitudinal patient information rather than answering isolated medical questions.
arXiv:2606. 14766v1 Announce Type: cross Abstract: Autonomous medical and robotic systems increasingly rely on intelligent perception and reasoning capabilities to interpret visual data and support clinical decision making.
MultiViewDx is a physician‑validated multimodal instruction dataset that links medical imaging studies with patient context and normalizes heterogeneous reports into an evidence‑linked workflow (evidence → findings → differential discussion → diagnosis). The dataset covers a wide range of imaging modalities and uses a unified image‑text retriever to ensure that instruction synthesis is grounded in source‑supported evidence. Fine‑tuned models on MultiViewDx achieve the highest average accuracy on four MedVQA benchmarks and receive the strongest overall rating on JAMA Clinical Challenge cases, with ablations confirming the importance of case‑level multi‑view organization and evidence‑linked reasoning.
The paper reviews how Large Language Models (LLMs) are being adapted for medical reasoning, moving beyond single-step answers to systems that can systematically, transparently, and verifiably reason. It introduces a taxonomy of enhancement techniques, split into training-time methods such as supervised fine‑tuning and reinforcement learning, and test-time methods like prompt engineering and multi‑agent systems. The review examines their application across text, image, and code modalities in key clinical areas—diagnosis, education, and treatment planning—and tracks the shift in evaluation benchmarks from simple accuracy to more nuanced assessments of reasoning quality and visual interpretability.
LingShu is a large-scale, symptom‑centric knowledge graph that bridges Traditional Chinese Medicine (TCM) and modern biomedicine. It contains 17.33 million entity records and 39.47 million relation records, combining 17.19 million semantic triples with 22.29 million contextualized quadruples to encode conditional medical associations. The graph integrates data from electronic medical records, TCM texts, biomedical ontologies, and curated knowledge bases, and is supported by a web platform offering visualization, reasoning, and evidence‑grounded question answering.
DeepTCM1.0 is a multi‑expert AI agent built on the DeepSeek V3.2 large language model, designed to integrate classical traditional Chinese medicine (TCM) theory with modern life sciences for mechanistic analysis of TCM compound formulas. The framework employs a three‑tier collaborative architecture and a three‑round iterative quality‑control workflow, simulating 11 interdisciplinary intelligent agents. It was validated on the Guizhi Decoction, with performance evaluated through double‑blind five‑dimensional scoring, ICC reliability testing, Mann‑Whitney U tests, and effect size analysis across 100 independent assessments by four large language models.
arXiv:2608.22713v1 Announce Type: new Abstract: Clinical diagnosis requires progressive integration of patient history, physical examination, laboratory findings, medical images, and diagnostic-infor...
arXiv:2608.22323v1 Announce Type: new Abstract: The application of Large Language Models (LLMs) to diagnostic decision-making has garnered growing interest. However, existing benchmarks largely focus...
arXiv:2605. 22547v3 Announce Type: replace-cross Abstract: Medical image diagnosis has achieved significant progress with deep learning, yet existing methods often rely on isolated visual evidence and lack the ability to effectively leverage similar cases and external knowledge.
arXiv:2607. 25933v1 Announce Type: cross Abstract: Clinical diagnostic evaluation should not only assess whether models can provide correct diagnoses, but also reflect the realities of clinical practice, including progressive disclosure of multimodal information, dynamic updating of diagnostic hypotheses, and continuous refinement of clinical reasoning.
PathPocket is a multimodal AI co‑pilot that grounds pathology decision‑making in evidence. It builds the largest pathology evidence corpus (≈110,472 documents) and a hypergraph of 4.55 million entities and 7.10 million relations to support traceable reasoning. The system handles text and multimodal queries, including ROI and gigapixel whole‑slide images, and outperforms current state‑of‑the‑art models on a benchmark of over 200,000 real‑world cases, improving pathologists’ diagnostic accuracy and confidence.
arXiv:2607. 15280v1 Announce Type: new Abstract: Sequential diagnosis requires balancing diagnostic accuracy against resource costs through iterative information gathering.