arXiv:2606. 02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs).
By Bo-Hong Wang, Baicheng Peng, Ruilin Wang, Jun Bai, Ziyang Song, Yue Li
arXiv:2508. 14817v2 Announce Type: replace-cross Abstract: Objective: To evaluate whether retrieval-augmented generation (RAG) can serve as an efficient alternative to long-context prompting for clinical reasoning over electronic health records (EHRs).
By Skatje Myers, Dmitriy Dligach, Timothy A. Miller, Samantha Barr, James Landefeld, Yanjun Gao, Matthew Churpek, Anoop Mayampurath, Majid Afshar
arXiv:2608.21810v1 Announce Type: cross
Abstract: Clinical decision-making is inherently experience-driven: physicians progressively refine their reasoning by synthesizing patient history, multimodal...
By Md Asaduzzaman Jabin, Khoa Le, Lin Zhao, Tianming Liu
arXiv:2609.14823v1 Announce Type: new
Abstract: Multimodal clinical decision-making requires reliable reasoning over heterogeneous evidence from electronic health records, medical images, and physiol...
By Ji Lu, Lifei Liu, Haoran Yu, Xianglong Wang, Yiru Fang, Kuo Yang, Huiran Duan, Jianping Gou
PathPocket is a multimodal AI co‑pilot that grounds pathology decision‑making in evidence. It builds the largest pathology evidence corpus (≈110,472 documents) and a hypergraph of 4.55 million entities and 7.10 million relations to support traceable reasoning. The system handles text and multimodal queries, including ROI and gigapixel whole‑slide images, and outperforms current state‑of‑the‑art models on a benchmark of over 200,000 real‑world cases, improving pathologists’ diagnostic accuracy and confidence.
By Zhe Xu, Zhengyu Zhang, Zhiyuan Cai, Jiahao Xu, Yijie Lin, Ziyi Liu, Junlin Hou, Hongyi Wang, Yuxiang Nie, Yihui Wang, Jiabo Ma, Ling Liang, Yingxue Xu, Zhengrui Guo, Guanghao Wu, Danyi Li, Ziqi Zhou, Donglin Tan, Zhijian Cen, Ying Tan, Xiaolin Liu, Qi Xie, Xiaoying Tang, Xi Peng, Cheng Deng, Lijuan Qu, Ronald Cheong Kin Chan, Li Liang, Hao Chen
MultiViewDx is a physician‑validated multimodal instruction dataset that links medical imaging studies with patient context and normalizes heterogeneous reports into an evidence‑linked workflow (evidence → findings → differential discussion → diagnosis). The dataset covers a wide range of imaging modalities and uses a unified image‑text retriever to ensure that instruction synthesis is grounded in source‑supported evidence. Fine‑tuned models on MultiViewDx achieve the highest average accuracy on four MedVQA benchmarks and receive the strongest overall rating on JAMA Clinical Challenge cases, with ablations confirming the importance of case‑level multi‑view organization and evidence‑linked reasoning.
By Junda Wang, Zonghai Yao, Yujan Ting, Eric Z. Chen, Hieu Tran, Hong Yu, Weijing Huang, Terrence Chen
arXiv:2609.39566v1 Announce Type: new
Abstract: Foundation models can serve as clinical agents through tool-use harnesses. However, conventional medical benchmarks assess reasoning over preselected e...
By Minye Shao, Chaohui Yu, Yixuan Wu, Fan Wang, Ling Shao, Yang Long
arXiv:2607. 09142v1 Announce Type: new Abstract: Large language models (LLMs) are increasingly deployed in online medical consultation, yet existing benchmarks remain poorly aligned with real clinical practice.
By Runhan Shi, Quan Zhou, Yuqian Xu, Shuai Yang, Xin Wu, Zitong Zhou, Hui Liu, Bin Cha, Zheming Wang, Liya Li, Wei Wei, Haoyuan Hu, Jun Xu
arXiv:2606. 08093v1 Announce Type: new Abstract: Pathology is the cornerstone of modern medicine, where accurate decision-making relies heavily on evidence-based practices.
By Zhe Xu, Zhengyu Zhang, Zhiyuan Cai, Jiahao Xu, Yijie Lin, Ziyi Liu, Junlin Hou, Hongyi Wang, Yuxiang Nie, Ling Liang, Yihui Wang, Yingxue Xu, Ronald Cheong Kin Chan, Li Liang, Hao Chen
arXiv:2607. 04907v1 Announce Type: new Abstract: Deploying Large Language Models (LLMs) in high-stakes clinical settings remains limited by structural hallucinations, weak deterministic reasoning over tabular patient data, and omissions in vector retrieval.
By Mohammed Saim Ahmed Quadri, Yunzhe Xue, Justin W. Ady, Usman Roshan
arXiv:2605. 22547v3 Announce Type: replace-cross Abstract: Medical image diagnosis has achieved significant progress with deep learning, yet existing methods often rely on isolated visual evidence and lack the ability to effectively leverage similar cases and external knowledge.
By Yiming Xu, Yixuan Liu, Yuhang Zhang, Ling Zheng, Yihan Wang, Qi Song
Lingshu is a medical‑specialized multimodal large language model that addresses key limitations of existing medical MLLMs, such as narrow knowledge coverage, hallucinations, and weak reasoning. The authors curate a comprehensive dataset combining medical imaging, texts, and general‑domain data, then train Lingshu in multiple stages to embed medical expertise and improve task performance. They also introduce MedEvalKit, a unified evaluation framework, and demonstrate that Lingshu outperforms current open‑source multimodal models on multimodal QA, text‑based QA, and medical report generation.
By Weiwen Xu, Hou Pong Chan, Long Li, Mahani Aljunied, Ruifeng Yuan, Jianyu Wang, Chenghao Xiao, Guizhen Chen, Chaoqun Liu, Zhaodonghui Li, Yu Sun, Junao Shen, Chaojun Wang, Jie Tan, Deli Zhao, Tingyang Xu, Hao Zhang, Yu Rong