PathPocket is a multimodal AI co‑pilot that grounds pathology decision‑making in evidence. It builds the largest pathology evidence corpus (≈110,472 documents) and a hypergraph of 4.55 million entities and 7.10 million relations to support traceable reasoning. The system handles text and multimodal queries, including ROI and gigapixel whole‑slide images, and outperforms current state‑of‑the‑art models on a benchmark of over 200,000 real‑world cases, improving pathologists’ diagnostic accuracy and confidence.
By Zhe Xu, Zhengyu Zhang, Zhiyuan Cai, Jiahao Xu, Yijie Lin, Ziyi Liu, Junlin Hou, Hongyi Wang, Yuxiang Nie, Yihui Wang, Jiabo Ma, Ling Liang, Yingxue Xu, Zhengrui Guo, Guanghao Wu, Danyi Li, Ziqi Zhou, Donglin Tan, Zhijian Cen, Ying Tan, Xiaolin Liu, Qi Xie, Xiaoying Tang, Xi Peng, Cheng Deng, Lijuan Qu, Ronald Cheong Kin Chan, Li Liang, Hao Chen
DentAgent is an evidence‑centric multi‑agent framework designed for multimodal dental reasoning. It coordinates five specialized agents that process domain knowledge, radiographs, intraoral photographs, and 3D dental data, converting observations into structured evidence records. The Evidence Blackboard tracks coverage, gaps, and conflicts before generating responses, and the system outperforms senior specialists by 17.3 percentage points on multi‑label diagnosis across four benchmarks.
By Zijie Meng, Xiwei Dai, Yixuan Tang, Jin Hao, Yang Feng, Fudong Zhu, Xiaoqiang Liu, Shaosheng Cao, Zuozhu Liu
arXiv:2606. 08093v1 Announce Type: new Abstract: Pathology is the cornerstone of modern medicine, where accurate decision-making relies heavily on evidence-based practices.
By Zhe Xu, Zhengyu Zhang, Zhiyuan Cai, Jiahao Xu, Yijie Lin, Ziyi Liu, Junlin Hou, Hongyi Wang, Yuxiang Nie, Ling Liang, Yihui Wang, Yingxue Xu, Ronald Cheong Kin Chan, Li Liang, Hao Chen
arXiv:2606. 14766v1 Announce Type: cross Abstract: Autonomous medical and robotic systems increasingly rely on intelligent perception and reasoning capabilities to interpret visual data and support clinical decision making.
By Hamza Riaz, Arham Haroon, Maha Baig, Muhammad Dawood Rizwan, Muhammad Naseer Bajwa, Muhammad Moazam Fraz
arXiv:2610.34599v1 Announce Type: new
Abstract: Despite advances in automated liver lesion segmentation, a gap remains between image-derived predictions and clinically interpretable radiology reports...
By Fatma Ahmed Mansour, Rahatara Ferdousi, Manar Fathy Elshenawy
The paper reviews how Large Language Models (LLMs) are being adapted for medical reasoning, moving beyond single-step answers to systems that can systematically, transparently, and verifiably reason. It introduces a taxonomy of enhancement techniques, split into training-time methods such as supervised fine‑tuning and reinforcement learning, and test-time methods like prompt engineering and multi‑agent systems. The review examines their application across text, image, and code modalities in key clinical areas—diagnosis, education, and treatment planning—and tracks the shift in evaluation benchmarks from simple accuracy to more nuanced assessments of reasoning quality and visual interpretability.
By Zizhan Ma, Wenxuan Wang, Meidan Ding, Shiyi Zheng, Shengyuan Liu, Jie Liu, Jiaming Ji, Linlin Shen, Yixuan Yuan, Wenting Chen
MultiViewDx is a physician‑validated multimodal instruction dataset that links medical imaging studies with patient context and normalizes heterogeneous reports into an evidence‑linked workflow (evidence → findings → differential discussion → diagnosis). The dataset covers a wide range of imaging modalities and uses a unified image‑text retriever to ensure that instruction synthesis is grounded in source‑supported evidence. Fine‑tuned models on MultiViewDx achieve the highest average accuracy on four MedVQA benchmarks and receive the strongest overall rating on JAMA Clinical Challenge cases, with ablations confirming the importance of case‑level multi‑view organization and evidence‑linked reasoning.
By Junda Wang, Zonghai Yao, Yujan Ting, Eric Z. Chen, Hieu Tran, Hong Yu, Weijing Huang, Terrence Chen
The paper introduces ReasonCVS, a structured reasoning framework for assessing the Critical View of Safety in laparoscopic cholecystectomy. It uses a Vision‑Language Model to build an Anatomical Scene Graph Abstraction and a Large Language Model–based Rationale‑Aware Reasoning Agent to verify sub‑criteria, producing a final verdict with traceable clinical rationale. Experiments on the Endoscapes‑CVS201 benchmark show ReasonCVS outperforms existing methods with a 68.1% mAP while offering interpretable, criterion‑level explanations.
By Qing Xu, Yuxiang Luo, Zhen Chen
arXiv:2603.22179v2 Announce Type: replace
Abstract: Cardiovascular disease remains the leading cause of global mortality, with progress hindered by human interpretation of complex cardiac tests. Curr...
By Jack W O'Sullivan, Mohammad Asadi, Lennart Elbe, Akshay Chaudhari, Tahoura Nedaee, Francois Haddad, Ivan Lopez, Fang Cao, Michael Salerno, Li Fe-Fei, Ehsan Adeli, Rima Arnaout, Euan A Ashley
A patient's pathology case spans tens of slides from distinct specimens and anatomical sites, each carrying non-redundant, site-specific evidence. Forming a patient-level conclusion therefore requires...
arXiv:2609.39566v1 Announce Type: new
Abstract: Foundation models can serve as clinical agents through tool-use harnesses. However, conventional medical benchmarks assess reasoning over preselected e...
By Minye Shao, Chaohui Yu, Yixuan Wu, Fan Wang, Ling Shao, Yang Long
arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.
By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi