arXiv Computation and Language

A Source-Grounded Framework for Constructing and Evaluating Progressive Multimodal Diagnostic Dialogues from Clinical Case Reports

arXiv AI
Jul 29

Evaluating Multi-Turn Multimodal Diagnostic Reasoning on Challenging Real-World Clinical Cases

arXiv:2607. 25933v1 Announce Type: cross Abstract: Clinical diagnostic evaluation should not only assess whether models can provide correct diagnoses, but also reflect the realities of clinical practice, including progressive disclosure of multimodal information, dynamic updating of diagnostic hypotheses, and continuous refinement of clinical reasoning.

By Rui Yang, Weihao Xuan, Yi Lin, Zhuhan Bao, Jonathan Chong Kai Liew, Matthew Yu Heng Wong, Nicol\'as Lescano, Nikita R. Paripati, Emily Ling-Lin Pai, Jiarui Liu, Heli Qi, Heng-Jui Chang, Benny Kai Guo Loo, Huitao Li, Kunyu Yu, Yufan Wang, Chuan Hong, Shijian Lu, Douglas Teodoro, Naoto Yokoya, Ross Koppel, Mona Diab, Hua Xu, David W. Bates, Nan Liu, Yifan Peng
arXiv AI
Aug 19

A Multimodal Agentic Pathology Co-pilot via Evidence Grounded Reasoning

PathPocket is a multimodal AI co‑pilot that grounds pathology decision‑making in evidence. It builds the largest pathology evidence corpus (≈110,472 documents) and a hypergraph of 4.55 million entities and 7.10 million relations to support traceable reasoning. The system handles text and multimodal queries, including ROI and gigapixel whole‑slide images, and outperforms current state‑of‑the‑art models on a benchmark of over 200,000 real‑world cases, improving pathologists’ diagnostic accuracy and confidence.

By Zhe Xu, Zhengyu Zhang, Zhiyuan Cai, Jiahao Xu, Yijie Lin, Ziyi Liu, Junlin Hou, Hongyi Wang, Yuxiang Nie, Yihui Wang, Jiabo Ma, Ling Liang, Yingxue Xu, Zhengrui Guo, Guanghao Wu, Danyi Li, Ziqi Zhou, Donglin Tan, Zhijian Cen, Ying Tan, Xiaolin Liu, Qi Xie, Xiaoying Tang, Xi Peng, Cheng Deng, Lijuan Qu, Ronald Cheong Kin Chan, Li Liang, Hao Chen
arXiv AI
Jun 30

IMCBench: A benchmark for multimodal LLMs in Image-grounded Medical Conversations

arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.

By Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Anchal Nema, Nivedita Wadhwa, Prashams S Jain, Rebecca Abraham, Will Kimbrough, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
arXiv AI
6d ago

MKG-CARE: Case-Aware Reasoning with Multimodal Knowledge Graphs for Explainable Medical Image Diagnosis

arXiv:2605. 22547v3 Announce Type: replace-cross Abstract: Medical image diagnosis has achieved significant progress with deep learning, yet existing methods often rely on isolated visual evidence and lack the ability to effectively leverage similar cases and external knowledge.

By Yiming Xu, Yixuan Liu, Yuhang Zhang, Ling Zheng, Yihan Wang, Qi Song
arXiv AI
Aug 11

Med-CRAFT: An Information System for Explainable and Configurable Construction of Multimodal Medical QA Datasets

arXiv:2512. 01045v2 Announce Type: replace Abstract: Data-intensive artificial intelligence applications increasingly rely on large-scale, high-quality, explainable, and reproducible datasets, yet the construction of such datasets often remains labor-intensive, weakly traceable, and difficult to configure.

By Shenxi Liu, Kan Li, Mingyang Zhao, Yuhang Tian, Bin Li
arXiv AI
Jul 13

MedRealMM: A Real-World Multimodal Benchmark for Chinese Online Medical Consultation

arXiv:2607. 09142v1 Announce Type: new Abstract: Large language models (LLMs) are increasingly deployed in online medical consultation, yet existing benchmarks remain poorly aligned with real clinical practice.

By Runhan Shi, Quan Zhou, Yuqian Xu, Shuai Yang, Xin Wu, Zitong Zhou, Hui Liu, Bin Cha, Zheming Wang, Liya Li, Wei Wei, Haoyuan Hu, Jun Xu
arXiv AI
Jun 16

XMedFusion: A Knowledge-Guided Multimodal Perception and Reasoning Framework for Autonomous Medical Systems

arXiv:2606. 14766v1 Announce Type: cross Abstract: Autonomous medical and robotic systems increasingly rely on intelligent perception and reasoning capabilities to interpret visual data and support clinical decision making.

By Hamza Riaz, Arham Haroon, Maha Baig, Muhammad Dawood Rizwan, Muhammad Naseer Bajwa, Muhammad Moazam Fraz
arXiv AI
Jun 11

OpenMedReason: Scientific Reasoning Supervision for Medical Vision-Language Models

arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.

By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv Computer Vision
2d ago

UR$^{2}$-MLLM: Uncertainty-aware Revisit Reasoning in Multimodal Large Language Models for Radiology Report Generation

The paper introduces UR$^{2}$-MLLM, an uncertainty‑aware multimodal large language model that dynamically revisits uncertain image regions during radiology report generation. It incorporates an uncertainty perception module trained on a specialized dataset, builds a multimodal reasoning trajectory with a detect‑and‑copy mechanism to guide revisits, and refines this behavior using a visual grounding reward via reinforcement learning. Experiments on MIMIC‑CXR and IU‑Xray demonstrate state‑of‑the‑art performance, underscoring the importance of visual revisit reasoning for reliable, clinically aligned reports.

By Yucheng Chen, Yang Yu, Jiazhou Zhou, Yufei Shi, Yongying Lan, Yichi Zhang, Liyi Li, Si Yong Yeo
arXiv AI
Aug 18

DiagnosisArena: Benchmarking Diagnostic Reasoning for Large Language Models

arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.

By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang