DeepTCM1.0 is a multi‑expert AI agent built on the DeepSeek V3.2 large language model, designed to integrate classical traditional Chinese medicine (TCM) theory with modern life sciences for mechanistic analysis of TCM compound formulas. The framework employs a three‑tier collaborative architecture and a three‑round iterative quality‑control workflow, simulating 11 interdisciplinary intelligent agents. It was validated on the Guizhi Decoction, with performance evaluated through double‑blind five‑dimensional scoring, ICC reliability testing, Mann‑Whitney U tests, and effect size analysis across 100 independent assessments by four large language models.
arXiv:2606. 06869v1 Announce Type: new Abstract: Aim: Existing AI-assisted traditional Chinese medicine diagnostic tools suffer from opaque reasoning processes, passive interaction, and limited treatment plan presentation.
arXiv:2609.17544v1 Announce Type: new Abstract: Large language models (LLMs) are increasingly being explored for clinical applications, yet their assessment for real-world traditional Chinese medicin...
The paper introduces a retrieval‑augmented multi‑agent framework that automatically generates instance‑specific evaluation rubrics for medical language models. By retrieving authoritative medical evidence, decomposing it into atomic facts, and combining these with user interaction constraints, the system produces fine‑grained criteria that outperform GPT‑4o on HealthBench and LLMEval‑Med. The generated rubrics also guide response refinement, improving medical LLM output quality by 9.2%.
LingShu is a large-scale, symptom‑centric knowledge graph that bridges Traditional Chinese Medicine (TCM) and modern biomedicine. It contains 17.33 million entity records and 39.47 million relation records, combining 17.19 million semantic triples with 22.29 million contextualized quadruples to encode conditional medical associations. The graph integrates data from electronic medical records, TCM texts, biomedical ontologies, and curated knowledge bases, and is supported by a web platform offering visualization, reasoning, and evidence‑grounded question answering.
arXiv:2603.08166v2 Announce Type: replace Abstract: Automated Drug Combination Extraction (DCE) from large-scale biomedical literature is crucial for advancing precision medicine and pharmacological...
arXiv:2607. 01814v1 Announce Type: new Abstract: Traditional Chinese Medicine (TCM) diagnosis, particularly through tongue inspection, faces persistent challenges in subjectivity and reproducibility.
arXiv:2606. 19245v1 Announce Type: new Abstract: Artificial intelligence (AI) agents promise to accelerate drug discovery by compressing interpretation and decision-making loops, but practical deployment requires trusted evaluation on realistic program decisions.
arXiv:2606. 15931v1 Announce Type: cross Abstract: Historical medical archives and traditional medicines hold immense potential for drug discovery and remain a primary source for current drug development.
arXiv:2510. 21084v3 Announce Type: replace-cross Abstract: Large language models (LLMs) have shown strong potential for clinical decision support through their advanced language understanding and reasoning capabilities.
Lingshu is a medical‑specialized multimodal large language model that addresses key limitations of existing medical MLLMs, such as narrow knowledge coverage, hallucinations, and weak reasoning. The authors curate a comprehensive dataset combining medical imaging, texts, and general‑domain data, then train Lingshu in multiple stages to embed medical expertise and improve task performance. They also introduce MedEvalKit, a unified evaluation framework, and demonstrate that Lingshu outperforms current open‑source multimodal models on multimodal QA, text‑based QA, and medical report generation.
arXiv:2503. 07459v3 Announce Type: replace-cross Abstract: Complex medical reasoning requires integrating heterogeneous clinical evidence across multiple inference steps.
arXiv:2607. 18249v1 Announce Type: cross Abstract: Constraint-based metabolic modeling is a powerful way to study the mechanistic basis of cellular states and disease, but its effective use demands substantial computational expertise and careful coordination of multi-step analyses.