The paper introduces Frequency-Based Probabilistic Ranker (FBPR), a lightweight method that uses smoothed Naive Bayes on concept‑diagnosis co‑occurrence statistics to score multiple‑choice clinical diagnosis questions. When trained on corpora such as Dolma and RedPajama, FBPR matches the performance of large language models (LLMs) on MedQA benchmarks. FBPR and LLMs answer largely different subsets of questions, and a simple hybrid of the two yields a notable performance gain.
arXiv:2601.03471v4 Announce Type: replace-cross Abstract: Reliable epidemiological reasoning requires synthesizing study evidence to infer disease burden, transmission dynamics, and intervention effe...
The paper introduces PrecepTron, a 32‑billion‑parameter language model fine‑tuned with low‑rank adaptation to evaluate clinical reasoning in large language models (LLMs) at a physician level. It also releases GRAND‑ROUNDS, a benchmark of 9,217 scored responses from 160 clinicians across seven studies. Using PrecepTron, the authors replicate key findings from major medical AI studies and explore new questions about LLM diagnostic accuracy, demonstrating that fine‑tuned models can provide consistent, scalable physician‑level scoring.
arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.
arXiv:2602. 12424v2 Announce Type: replace-cross Abstract: Benchmarks establish a standardized evaluation framework to systematically assess the performance of large language models (LLMs), facilitating objective comparisons and driving advancements in the field.
MTDiag is a newly released multi-turn diagnostic dialogue dataset designed to evaluate large language models (LLMs) in clinically meaningful ways. It is built from DDXPlus, MIMIC-IV, and AJCR case reports, covering both common emergency department presentations and rare conditions, and normalizes cases into a canonical schema using UMLS concept identifiers and ICD-10 codes. The dataset includes a UserLM‑8B utterance‑generation pipeline and physician‑validated natural‑language utterances, and introduces clinical knowledge‑grounded metrics that go beyond simple diagnostic accuracy for multi‑turn differential diagnosis tasks.
arXiv:2608. 16643v1 Announce Type: cross Abstract: Automated detection of errors in clinical documentation is a promising application of large language models (LLMs), yet decisions to deploy such models rest on benchmarks that evaluate each clinical note in isolation.
arXiv:2606. 15735v1 Announce Type: cross Abstract: Discharge summaries are crucial clinical documents containing the context of a patient's overall hospital stay, and are routinely reviewed by medical experts for patient readmission, ongoing care, and diagnostic decision-making.
The paper proposes a behavior-based fusion model that combines large language models (LLMs) with ontology rankers to improve rare-disease diagnosis. By examining ranked lists, agreement, and ontology support, the model learns how much to rely on each system per case, achieving significant recall gains on Phenopacket Store and RAMEDIS benchmarks. Importantly, the fused diagnoses retain candidate-level ontology evidence for inspection.
arXiv:2606. 18933v1 Announce Type: new Abstract: Active feature acquisition (AFA) sequentially selects which features to observe to reach a classification or ranking decision.
arXiv:2608.29582v1 Announce Type: cross Abstract: Current evaluations of large language models (LLMs) primarily focus on factual knowledge retrieval, overlooking the fundamental challenge of navigati...
RetiJev is a family of 0.8B‑9B decision models designed for ophthalmic clinical decision support, offering fast, accurate, and privacy‑preserving inference without autoregressive decoding. The authors created RetiJev‑Data, a source‑grounded corpus of 78,158 clinical‑decision and diagnosis questions, 50,074 guideline‑grading questions, and a 24,662‑question evaluation benchmark. RetiJev outperforms a 27B LLM and the commercial Jev 1.13 model on guideline grading and clinical decisions, achieving the highest accuracy while answering a case in 158 ms on a single GPU—3.5× faster than LLM generation and 470× faster than reasoning.
The paper investigates the "score granularity gap" in black-box large language model (LLM) classifiers, asking how finely a confidence score can be thresholded for deployment. By comparing seven confidence construction methods across 25 model-dataset pairs, the authors find that single-shot verbalized confidence, when properly converted to a probability, ranks well but offers only a few distinct threshold values, limiting operational flexibility. The study also shows that multi-query aggregation can improve weak models but may harm strong ones, and provides concrete guidance for deployment trade-offs.