arXiv AI By Furong Jia, Yuan Pu, Finn Guo, Monica Agrawal

Counting Clues: A Lightweight Probabilistic Baseline Can Match an LLM

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The paper introduces Frequency-Based Probabilistic Ranker (FBPR), a lightweight method that uses smoothed Naive Bayes on concept‑diagnosis co‑occurrence statistics to score multiple‑choice clinical diagnosis questions. When trained on corpora such as Dolma and RedPajama, FBPR matches the performance of large language models (LLMs) on MedQA benchmarks. FBPR and LLMs answer largely different subsets of questions, and a simple hybrid of the two yields a notable performance gain.

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arXiv AI
Oct 2

Scaling Clinical Judgment to Evaluate Medical AI

The paper introduces PrecepTron, a 32‑billion‑parameter language model fine‑tuned with low‑rank adaptation to evaluate clinical reasoning in large language models (LLMs) at a physician level. It also releases GRAND‑ROUNDS, a benchmark of 9,217 scored responses from 160 clinicians across seven studies. Using PrecepTron, the authors replicate key findings from major medical AI studies and explore new questions about LLM diagnostic accuracy, demonstrating that fine‑tuned models can provide consistent, scalable physician‑level scoring.

By Thomas A. Buckley, Zahir Kanjee, Peter G. Brodeur, Byron Crowe, Anthony M. Pettinato, Aashna P. Shah, Adrian D. Haimovich, Liam G. McCoy, Daniel Restrepo, Jason A. Freed, Ethan Goh, Jonathan H. Chen, Laura Zwaan, Katherine E. Goodman, Daniel J. Morgan, Raja-Elie E. Abdulnour, Adam Rodman, Arjun K. Manrai
arXiv AI
Aug 18

DiagnosisArena: Benchmarking Diagnostic Reasoning for Large Language Models

arXiv:2505. 14107v5 Announce Type: replace-cross Abstract: The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios.

By Yakun Zhu, Zhongzhen Huang, Linjie Mu, Yutong Huang, Wei Nie, Jiaji Liu, Shaoting Zhang, Pengfei Liu, Xiaofan Zhang
arXiv AI
Jun 10

RankLLM: Weighted Ranking of LLMs by Quantifying Question Difficulty

arXiv:2602. 12424v2 Announce Type: replace-cross Abstract: Benchmarks establish a standardized evaluation framework to systematically assess the performance of large language models (LLMs), facilitating objective comparisons and driving advancements in the field.

By Ziqian Zhang, Xingjian Hu, Yue Huang, Kai Zhang, Ruoxi Chen, Yixin Liu, Qingsong Wen, Kaidi Xu, Xiangliang Zhang, Neil Zhenqiang Gong, Lichao Sun
arXiv Computation and Language
Aug 27

MTDiag: A Multi-Turn Diagnostic Dataset Towards Clinically Meaningful LLM Evaluation

MTDiag is a newly released multi-turn diagnostic dialogue dataset designed to evaluate large language models (LLMs) in clinically meaningful ways. It is built from DDXPlus, MIMIC-IV, and AJCR case reports, covering both common emergency department presentations and rare conditions, and normalizes cases into a canonical schema using UMLS concept identifiers and ICD-10 codes. The dataset includes a UserLM‑8B utterance‑generation pipeline and physician‑validated natural‑language utterances, and introduces clinical knowledge‑grounded metrics that go beyond simple diagnostic accuracy for multi‑turn differential diagnosis tasks.

By Pia Chouayfati, Alexander M. Fichtl, Miriam Ansch\"utz, George Doumat, Georg Groh