arXiv:2607. 13984v1 Announce Type: cross Abstract: Longitudinal tumor measurements, dropout information, and genetic covariates provide complementary information about treatment response, but integrating these data sources within a single population modeling framework remains challenging.
By Anders Sj\"oberg, Nils Olsson, Marcus Baaz, Mats Jirstrand
arXiv:2608. 03145v1 Announce Type: new Abstract: Deep learning models can predict cancer recurrence from H&E stained slides, but the localized molecular states underlying these predictions remain largely obscured.
By Yesung Cho, Ji Hwan Park, Chanil Kim, Hyewon Kim, Honglan Li, Yumin Lee, Geongyu Lee, Sujeong Hong, Seong Min Park, Yoonyoung Lee, Hee Sool Rho, Sumin Lee, Amos Chungwon Lee, Changhwan Lee, Hwanyoung Shim, Hyunwook Kim, Hyeji Shin, Sanha Park, Jihoon Yu, Yoon Hee Shin, Sooheon Kim, Hyunjin Park, Seung Min Park, Sangwan Kim, Yujung Kim, Sung-Im Do, Eun-Young Kim, Dongmyung Shin, Jongbae Park, In-Gu Do
arXiv:2603. 01250v2 Announce Type: replace-cross Abstract: Breast cancer is the most frequently diagnosed malignancy among women worldwide and a leading cause of cancer-related mortality.
By Lidia Garrucho, Smriti Joshi, Kaisar Kushibar, Richard Osuala, Maciej Bobowicz, Xavier Bargall\'o, Paulius Jaru\v{s}evi\v{c}ius, Kai Geissler, Raphael Sch\"afer, Muhammad Alberb, Tony Xu, Anne Martel, Daniel Sleiman, Navchetan Awasthi, Hadeel Awwad, Joan C. Vilanova, Robert Mart\'i, Daan Schouten, Jeong Hoon Lee, Mirabela Rusu, Eleonora Poeta, Luisa Vargas, Eliana Pastor, Maria A. Zuluaga, Jessica K\"achele, Dimitrios Bounias, Alexandra Ertl, Katarzyna Gwo\'zdziewicz, Maria-Laura Cosaka, Pasant M. Abo-Elhoda, Sara W. Tantawy, Shorouq S. Sakrana, Norhan O. Shawky-Abdelfatah, Amr Muhammad Abdo-Salem, Androniki Kozana, Eugen Divjak, Gordana Ivanac, Katerina Nikiforaki, Michail E. Klontzas, Rosa Garc\'ia-Dosd\'a, Meltem Gulsun-Akpinar, O\u{g}uz Lafc{\i}, Carlos Mart\'in-Isla, Oliver D\'iaz, Laura Igual, Karim Lekadir
arXiv:2606. 29977v1 Announce Type: cross Abstract: Objectives: To characterize residual false positives in prostate MRI detection, and to evaluate a lightweight post-hoc refinement head for case-level specificity.
By Yongbo Shu, Kewen Chen, Yifeng Yuan, Zirui Xin, Luo Lei, Yang Yang, Xi Chen, Aijing Luo
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
By Jingyu Hu, Giuseppe Tripodi, Reed Naidoo, Sarah F. McGough, Tapabrata Chakraborti
arXiv:2607. 19137v1 Announce Type: cross Abstract: Inferring contrast enhancement from one pre-contrast breast MRI slice is underdetermined: post-contrast appearance contains physiological information that is not uniquely encoded in baseline anatomy.
By Andrea Borghesi, Xin Wang, Jonas Teuwen, George Yiasemis
Accurate prediction of patient-specific therapeutic response from pre-treatment transcriptomes is hindered by the scarcity of matched clinical response labels and post-treatment molecular profiles. Preclinical transfer-learning models can simulate drug-induced expression changes but are often hard to interpret and unstable, whereas knowledge-graph methods provide mechanistic context yet remain static and fail to capture drug-induced transcriptomic perturbation dynamics.
Objectives: To characterize residual false positives in prostate MRI detection, and to evaluate a lightweight post-hoc refinement head for case-level specificity. Materials and Methods: This retrospective study used PI-CAI (5-fold cross-validation) and Prostate158 (n=158; external).
arXiv:2607. 25497v1 Announce Type: cross Abstract: Pathology foundation models are approaching clinical deployment, yet remain vulnerable to systematic non-biological variation across centres.
By Cl\'ement Grisi, Jeroen van der Laak, Geert Litjens
Breast DCE-MRI AI is increasingly being explored for breast-level classification of no-lesion, benign, and malignant findings, beyond conventional lesion-centered diagnosis. Within this broader diagnostic scope, however, patient-specific background variability remains a major source of imaging confounding across classification tasks.
arXiv:2607. 29394v1 Announce Type: cross Abstract: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer management, but reliance on gadolinium-based contrast agents (GBCAs) restricts use in contraindicated populations, prolongs scan protocols, and presents environmental toxicity concerns.
By Smriti Joshi, Apostolia Tsirikoglou, Daniel M. Lang, Richard Osuala, Noah M\'arquez Varaa, Alejandro Guzman, Grzegorz Skorupko, Sebastian Ibarra Arregui, Lidia Garrucho, Akane Ohashi, Dimitra Ntoula, Eugen Divjak, O\u{g}uz Lafc{\i}, Jan C. Peeken, Julia A. Schnabel, Fredrik Strand, Oliver Diaz, Karim Lekadir
arXiv:2606. 11876v1 Announce Type: cross Abstract: Circulating-tumour DNA (ctDNA) carries evidence of drug resistance months before imaging shows it, but the earliest evidence lives below the assay's limit of detection (LoD): a nascent subclone is detected only intermittently, producing a flickering sequence of faint detects and non-detects.
By Aarchi Singh Thakur, Abhijoy Sarkar