arXiv:2510. 15042v3 Announce Type: replace-cross Abstract: In the 3D medical image domain, vision-language pre-training is used to create vision-language encoders (VLEs) that can support radiologists by retrieving patients with similar abnormalities, predicting likelihoods of abnormality, or, with downstream adaptation, generating radiological reports.
By Tassilo Wald, Ibrahim Ethem Hamamci, Yuan Gao, Sam Bond-Taylor, Harshita Sharma, Maximilian Ilse, Cynthia Lo, Olesya Melnichenko, Anton Schwaighofer, Noel C. F. Codella, Maria Teodora Wetscherek, Klaus H. Maier-Hein, Panagiotis Korfiatis, Valentina Salvatelli, Javier Alvarez-Valle, Fernando P\'erez-Garc\'ia
Vision-language pre-training (VLP) holds great promise for general-purpose medical AI by leveraging radiology reports as rich textual supervision, yet existing methods struggle with 3D CT imaging due to inefficient visual backbones and coarse semantic alignment. To address these issues, we propose a tailored VLP framework featuring three key components: (1) a CNN-ViT hybrid encoder that replaces ViT's patch embedding with a 3D CNN backbone to efficiently capture local anatomical details while preserving global attention and compatibility with pre-trained cross-modal priors; (2) a disease-level contrastive learning mechanism using learnable query tokens to dynamically extract disease-specific semantics from full reports and align them with corresponding visual features, thereby disentangling distinct diseases within the same anatomical region; and (3) a diagnosis-aware prompt strategy that employs real clinical phrases and aggregated disease prototypes to bridge the pre-training-inference gap and enhance zero-shot diagnostic reliability.
arXiv:2607. 27154v1 Announce Type: cross Abstract: CT vision-language foundation models have demonstrated promising performance across downstream tasks, but are typically trained with whole-volume representations that dilute fine-grained anatomical signals.
By Roshan Kenia, Stephanie L McNamara, William Lotter
arXiv:2608. 05960v1 Announce Type: cross Abstract: Routine CT interpretation is inherently comprehensive, capturing incidental findings across the entire scan volume.
By Maulik Chevli, Johannes Brandt, Rickmer Braren, Daniel Rueckert, Philip M\"uller
arXiv:2608. 03890v1 Announce Type: cross Abstract: A clinically useful chest X-ray system must go beyond fluent report generation: it should classify findings with tunable decision thresholds, localize them spatially, and derive the anatomical measurements upon which many diagnoses depend.
By Mercy Prasanna Ranjit, Anirban Porya, Sathvik Joel, Niharika Vadlamudi, Nikhilesh Chowdary Eathamukkala, Prasanth V V, Abhyuday Kumara Swamy, Pranay Narhari Umredkar, Pradeep Narayan, Vivek Rajagopal, Tanuja Ganu
arXiv:2608. 08713v1 Announce Type: cross Abstract: Vision-language models offer a promising path toward automating radiology report generation, but applying them to full 3D CT volumes poses substantial computational challenges.
By Jonathan Suprijadi, Raphael Stock, Moritz Langenberg, David Zimmerer, Kim-Celine Kahl, Stefan Denner, Yannick Kirchhoff, Karol Gotkowski, Maximilian Rokuss, Jeremias Traub, Tassilo Wald, Constantin Ulrich, Klaus Maier-Hein
arXiv:2608. 04472v1 Announce Type: cross Abstract: The development of foundation models (FMs) is crucial for advancing endoscopic image analysis.
By Zhenyu Yi, Jianwei Xu, Yue Hu, Zhongwei Qiu, Sijing Li, Liang Huang, Bin Lv, Ling Zhang, Yingda Xia
arXiv:2607. 20993v1 Announce Type: cross Abstract: Large vision-language models are becoming increasingly dominant in 3D medical image interpretation, but we rarely know which internal units encode clinical findings or where that information lives in the representation.
By Farhad Nooralahzadeh, Lea Bogensperger, Christian Bluethgen, Michael Krauthammer
arXiv:2506. 00633v3 Announce Type: replace-cross Abstract: Generating semantically controllable 3D CT volumes from radiology reports requires more than a rich text encoder, it requires vision-language alignment grounded in volumetric space.
By Daniele Molino, Camillo Maria Caruso, Filippo Ruffini, Paolo Soda, Valerio Guarrasi
arXiv:2606. 20477v1 Announce Type: cross Abstract: We study how to train visually grounded vision-language models (VLMs) for radiology without manual spatial annotations.
By Yusuf Salcan (Computer Vision Group, University of Freiburg, Germany, CRIION-AI Lab, Freiburg, Germany), Simon Ging (Computer Vision Group, University of Freiburg, Germany, Adaptive & Agentic AI), Robin Schirrmeister (Department of Radiology, Medical Center -- University of Freiburg, Germany), Philipp Arnold (Department of Radiology, Medical Center -- University of Freiburg, Germany), Elmar Kotter (Department of Radiology, Medical Center -- University of Freiburg, Germany), Behzad Bozorgtabar (Adaptive & Agentic AI), Thomas Brox (Computer Vision Group, University of Freiburg, Germany)
arXiv:2608. 00147v1 Announce Type: cross Abstract: Vision-language pretraining learns rich medical image representations from radiology reports, but previous model variants commonly operate within a single shared embedding space, so concept-level structure and interpretability must be recovered post hoc, limiting model transparency and, hence, clinical utility.
By Fabian Drexel, Marlene Fritzsche, Era Stambollxhiu, Miriam Kumpf, Lena Schmitzer, Lea Schumann, Jannik Kahmann, Friedrich Puttkammer, Johannes Moll, Jannik L\"ubberstedt, Zeineb Ben Chaaben, Anirudh Narayanan, Cosmin I. Bercea, Sebastian Ziegelmayer, Marcus R. Makowski, Daniel Rueckert, Lisa C. Adams, Keno K. Bressem
arXiv:2605. 30716v2 Announce Type: replace-cross Abstract: Generating clinically useful pathology reports for pathology cases from whole-slide images (WSIs) is challenging due to gigapixel resolution, long visual-token sequences, and the complexity of case-level reasoning, where a single case may contain multiple WSIs with heterogeneous tissues and ambiguous findings.
By Zhiyuan Yang, Jiahao Cheng, Vincent Quoc-Huy Trinh, Mahdi S. Hosseini