arXiv AI

Semi-Supervised Learning-Based Genetic Biomarkers Dataset for Multiple-Stage Hepatocellular Carcinoma Prediction

The article introduces a new dataset for hepatocellular carcinoma (HCC) prediction, comprising 770 patient samples with 11,150 gene expression levels each, categorized into five classes from normal tissue to various HCC stages. The dataset was constructed using XGBoost and semi‑supervised learning on three existing genomic biomarker datasets, leveraging their labels to generate new annotations. The resulting XGBoost model achieved a 96.5% classification accuracy during the semi‑supervised training process.

arXiv AI

Sep 15

Potential of Artificial Intelligence Algorithms for Identification of Relevant Diagnostic and Prognostic Biomarkers of Early-Stage Liver Cancer

This study investigates deep learning and explainable AI methods to diagnose hepatocellular carcinoma (HCC) and identify diagnostic and prognostic biomarkers across five disease stages using a transcriptomic dataset built via semi‑supervised learning. The best model used 15 genes selected by SelectKBest, achieving 90.74% accuracy, while a 20‑gene model had the lowest loss of 0.3187. SHAP‑based XAI highlighted DNAJB14 as the most influential gene, and functional validation showed that inhibiting DNAJB14 reverses key malignant traits of HCC cells.

By Ali Bou Nassif, Darko Castven, Manar Abu Talib, Jibran Sualeh Muhammad, Ahmed Ammar Kubba, Jens Marquardt, Abdalla Sayed Ali

safety

arXiv Machine Learning

Aug 18

AMPLIFAI: A Multiphase CT Dataset for Benchmarking Clinical Reasoning in LI-RADS Assessment of Liver Lesions

The paper introduces AMPLIFAI, the first public dataset of multiphase abdominal CT scans annotated with LI-RADS categories and segmented for three key LI-RADS features: arterial phase hyperenhancement, washout, and enhancing capsule. It outlines the dataset’s composition, curation process, and annotation pipeline following the Datasheets for Datasets format to promote transparency and reproducibility. The dataset aims to support the development of AI models for automated hepatocellular carcinoma diagnosis using the biopsy‑free, imaging‑based LI‑RADs framework.

By Pranav Kulkarni, Nikhil Shah, Amritansh Suryavanshi, Jana Delfino, James Tonascia, Jade Wong-You-Cheong, Barton Lane, Joseph Chirico, Jeffrey D. Hirsch, Ang Li, Heng Huang, Florence X. Doo

benchmarks

arXiv AI

Jul 7

Semantic Segmentation-Driven Image-Level Diagnosis of Liver Cancers in Hematoxylin and Eosin Histopathology Images

arXiv:2607. 03253v1 Announce Type: cross Abstract: As hematoxylin & eosin (H&E) staining constitutes the primary entry point in routine diagnostic workflows, computer-aided diagnosis from whole-slide H&E images is of particular clinical relevance.

By Ivica Kopriva, Dario Sitnik, Arijana Pacic, Karolina Krstanac, Irena Veliki Dalic, Marijana Popovic Hadzija

computer-vision

arXiv Computer Vision

Aug 25

Exploring learning environments for label\-efficient cancer diagnosis

arXiv:2408.07988v3 Announce Type: replace Abstract: Despite significant research efforts and advancements, cancer remains a leading cause of mortality. Early cancer prediction has become a crucial fo...

By Samta Rani, Tanvir Ahmad, Sarfaraz Masood, Chandni Saxena

llms

Hugging Face Trending Papers

Jun 25

Explainable Ensemble-Based Machine Learning Models for Detecting the Presence of Cirrhosis in Hepatitis C Patients

Hepatitis C is a liver infection caused by a virus, which results in mild to severe inflammation of the liver. Over many years, hepatitis C gradually damages the liver, often leading to permanent scarring, known as cirrhosis.

arXiv AI

Jun 26

Explainable Ensemble-Based Machine Learning Models for Detecting the Presence of Cirrhosis in Hepatitis C Patients

arXiv:2606. 26561v1 Announce Type: new Abstract: Hepatitis C is a liver infection caused by a virus, which results in mild to severe inflammation of the liver.

By Abrar Alotaibi, Lujain Alnajrani, Nawal Alsheikh, Alhatoon Alanazy, Salam Alshammasi, Meshael Almusairii, Shoog Alrassan, Aisha Alansari

Hugging Face Trending Papers

Jul 14

CRC-HGD: A Histopathological Image Dataset for Grading Colorectal Cancer

Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related deaths globally, with approximately 1,926,425 new cases and 904,019 deaths reported in 2022. Accurate histologic grading plays a critical role in prognosis and treatment planning for colorectal adenocarcinoma.

arXiv AI

Jul 21

Benchmarking Machine Learning Models for Multi-Omics-Based Breast Cancer Prediction

arXiv:2607. 16250v1 Announce Type: cross Abstract: Estrogen Receptor (ER) status is a critical biomarker in breast cancer diagnosis, prognosis, and treatment selection.

By Priyanka Paudel, Madan Baduwal

efficiency benchmarks

arXiv Computer Vision

Sep 16

CRC-HGD: A Histopathological Image Dataset for Grading Colorectal Cancer

arXiv:2607.12750v3 Announce Type: replace Abstract: Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related deaths globally, with approximatel...

By Elham Amjadi, Amin Bahreini, Sayed Mohammad Hasan Emami, Sayyed Mohammadreza Hakimian, Alireza Fahim, Hojjatollah Rahimi, Hamidreza Bolhasani

arXiv AI

Jun 10

Conformal Risk Prediction for Non-Alcoholic Fatty Liver Disease Using Gradient Boosting with Distribution-Free Coverages

arXiv:2606. 09860v1 Announce Type: cross Abstract: Non-alcoholic fatty liver disease (NAFLD) affects roughly 25% of global adults, posing substantial hepatic and cardiovascular risks.

By Xinze Zhang

arXiv Machine Learning

Jun 2

Early Prediction of Liver Cirrhosis Up to Two Years in Advance: A Machine Learning Study Benchmarking Against the FIB-4 and APRI Scores

arXiv:2601. 00175v2 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years prior to diagnosis using routinely collected electronic health record (EHR) data and benchmark their performance against the FIB-4 and APRI clinical scores.

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed

benchmarks

arXiv Machine Learning

4d ago

Does Machine Learning Outperform Traditional Fibrosis Scores in Predicting Liver Cirrhosis Risk? A Longitudinal EHR-Based Study

arXiv:2601.00175v3 Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years before diagnosis using...

By Zhuqi Miao, Ahmed G Qasem, Sujan Ravi, Jason T. Cheng, Abdulaziz Ahmed, Courtney W. Houchen, Sumayah Abed, Dilorom Azimdjanovna Zuparova, Abdulaziz Ahmed

Related stories